2019 Fiscal Year Final Research Report
Investigations for Effective Therapies for Human Parechovirus Type 3 Infection
| Project/Area Number |
17H04226
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
渡邉 香奈子 新潟大学, 医歯学系, 准教授 (80626094)
今井 千速 新潟大学, 医歯学系, 准教授 (90419284)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Keywords | パレコウイルスA3 / 新生児 / 乳児 / 治療 |
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| Outline of Final Research Achievements |
There has been no specific treatment for parechovirus-A3 (PeV-A3) infection, which causes severe infection in neonates and young infants. We evaluated the effectiveness of antimicrobials for PeV-A3 using in vitro models. As a results, we found inhibition effects of soem antimicrobials for PeV-A3. These medications could lead to the future treatment strategies for PeV-A3 infection.
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| Free Research Field |
小児感染症
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| Academic Significance and Societal Importance of the Research Achievements |
新生児、早期乳児に重症感染症をきたすパレコウイルスA3（PeV-A3)に対して、効果の期待できる薬剤の候補がIn vitroの実験細胞を用いた実験で見つかったことで、今後のPeV-A3感染症の治療戦略に役立つ可能性がある。今後、PeV-A3の迅速な診断の下、治療薬の投与のタイミングについて検討する必要がある。
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