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2019 Fiscal Year Final Research Report

Development of care bundle for preventing wound infection based on bedside biofilm detection

Research Project

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Project/Area Number 17H04455
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Gerontological nursing
Research InstitutionThe University of Tokyo

Principal Investigator

Nakagami Gojiro  東京大学, 大学院医学系研究科(医学部), 准教授 (70547827)

Co-Investigator(Kenkyū-buntansha) 真田 弘美  東京大学, 大学院医学系研究科(医学部), 教授 (50143920)
峰松 健夫  東京大学, 大学院医学系研究科(医学部), 特任准教授 (00398752)
須釜 淳子  金沢大学, 新学術創成研究機構, 教授 (00203307)
Project Period (FY) 2017-04-01 – 2020-03-31
Keywordsバイオフィルム / ブロッティング / デブリードマン / 緑膿菌 / 褥瘡 / 糖尿病足潰瘍 / 異分野融合 / ポイントオブケア
Outline of Final Research Achievements

The detection of biofilm as a cause of pressure ulcer infection has been based on invasive and time-consuming methods such as tissue biopsy. The limited availability of biofilm examinations made clinical observation impossible. In this study, we have developed a non-invasive, point-of-care bedside biofilm detection technology. We visualize the biofilm using blotting membrane applied to a wound and stained for a very short time. We have confirmed the concurrent and predictive validity of biofilm detection methods (animal studies, clinical studies). The implementation of a wound care system based on the results of biofilm detection at the bedside could significantly accelerate wound healing in chronic wounds. The system is currently on the market as a biofilm detection tool.

Free Research Field

看護理工学

Academic Significance and Societal Importance of the Research Achievements

従来不可能であったバイオフィルムの可視化をベッドサイドで可能としたことにより、これまで経験的に行われてきた「創の清浄化」という最も基本的な創傷ケアに変革をもたらした。これは看護技術の本質である非侵襲的、リアルタイムケアを基本とした、褥瘡感染の病態に迫る本質的で合理的なアセスメント技術といえる。これにより、創傷ケアにかかる患者の負担の軽減ならびに医療費の削減に直結するであろう。

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Published: 2021-02-19  

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