2021 Fiscal Year Final Research Report
Search for genetic capacitor
| Project/Area Number |
17H05014
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Evolutionary biology
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| Research Institution | Kanagawa University (2020-2021)
Okayama University (2017-2019) |
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Principal Investigator |
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| Project Period (FY) |
2017-04-01 – 2021-03-31
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| Keywords | 隠蔽変異 / HSP90 / ゲノムワイド関連解析 |
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| Outline of Final Research Achievements |
For organisms, heritability of shape and size is one of the factors that directly affects the rate of evolution. For example, if certain traits such as morphology, body color or behavior is easy to inherit and certain trait value is more advantageous, it is expected that the traits of the organism will evolve quickly in a certain direction. In this research, I aimed to understand the genetic mechanism controlling heritability. As a result, it was confirmed that there are multiple genes on the genome thought to have such functions.
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| Free Research Field |
進化生物学
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| Academic Significance and Societal Importance of the Research Achievements |
本研究では、分子シャペロンの一つであるHSP90が様々な形質の「遺伝しやすさ」に影響することをゲノム網羅的なアプローチによって示した。ゲノムの塩基配列とその結果として生じる形質の関係は必ずしも厳密に決定されている訳では無い事、また、HSP90の制御対象がゲノム全域に及んでいる可能性が示唆された。本研究で得られた知見は、生物の進化可能性に関する基礎的な理解を進めるだけでなく、育種における複雑な人為淘汰の効率化にもつながる可能性がある。
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