2019 Fiscal Year Annual Research Report

Development of a hybrid tomosynthesis and acoustic imaging modality for early detection of breast cancer

Research Project

Project/Area Number	17H05075
Research Institution	Hokkaido University
Principal Investigator	彭浩北海道大学, 国際連携研究教育局, 招へい教員 (70790195)
Project Period (FY)	2017-04-01 – 2020-03-31
Keywords	breast imaging / x-ray acoustic / molecular imaging / spatial resolution / contrast recovery
Outline of Annual Research Achievements	System design from signal induction to readout electronics was completed. Monte Carlo simulation of X-ray transport and interaction, as well as that for acoustic wave propagation are being performed to model sensitivity and spatial resolution needs on both the X-ray and acoustic sides for breast imaging purposes using GATE, k-Wave, MATLAB, and virtual breast phantoms. A noise-equivalent pressure (NEP) / signal-to-noise ratio (SNR) framework has been developed, showing potential for NEP to be <1 Pa dependent on area of transducer surface. The optimum configurations of the system, in terms of image SNR and contrast-to-noise ratio (CNR) have been investigated, with the goal being to differentiate between breast tissue subgroups of different molecular densities.
Research Progress Status	令和元年度が最終年度であるため、記入しない。
Strategy for Future Research Activity	令和元年度が最終年度であるため、記入しない。