2019 Fiscal Year Annual Research Report

Development of a hybrid tomosynthesis and acoustic imaging modality for early detection of breast cancer

Research Project

Project/Area Number	17H05075
Research Institution	Hokkaido University
Principal Investigator	彭浩北海道大学, 国際連携研究教育局, 招へい教員 (70790195)
Project Period (FY)	2017-04-01 – 2020-03-31
Keywords	breast imaging / x-ray acoustic / molecular imaging / spatial resolution / contrast recovery
Outline of Annual Research Achievements	System design from signal induction to readout electronics was completed. Monte Carlo simulation of X-ray transport and interaction, as well as that for acoustic wave propagation are being performed to model sensitivity and spatial resolution needs on both the X-ray and acoustic sides for breast imaging purposes using GATE, k-Wave, MATLAB, and virtual breast phantoms. A noise-equivalent pressure (NEP) / signal-to-noise ratio (SNR) framework has been developed, showing potential for NEP to be <1 Pa dependent on area of transducer surface. The optimum configurations of the system, in terms of image SNR and contrast-to-noise ratio (CNR) have been investigated, with the goal being to differentiate between breast tissue subgroups of different molecular densities.
Research Progress Status	令和元年度が最終年度であるため、記入しない。
Strategy for Future Research Activity	令和元年度が最終年度であるため、記入しない。

(4 results)