2021 Fiscal Year Final Research Report
Ultility of prelaod stress echocardiography in patrients with chronic heart failure
Project/Area Number |
17K01412
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Medical systems
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Research Institution | The University of Tokushima |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
山田 博胤 徳島大学, 大学院医歯薬学研究部(医学域), 特任教授 (40380084)
瀬野 弘光 徳島大学, 病院, 医員 (10794026)
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Project Period (FY) |
2021-01-01 – 2022-03-31
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Keywords | 心不全 / 心エコー / 下肢陽圧 / リスク層別化 |
Outline of Final Research Achievements |
Our research group first examined the usefulness of the positive pressure echocardiography in patients with heart failure with preserved left ventricular ejection fraction. The present study shows that the positive pressure echocardiography enables us to detect a high-risk group for worsening heart failure by measuring hemodynamic changes when preload increases.
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Free Research Field |
循環器内科
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Academic Significance and Societal Importance of the Research Achievements |
心不全の予後は不良であり,早期の心機能障害を検出し治療介入をおこなう必要がある.本研究を通じて,下肢陽圧負荷心エコー図検査が高い安全性を有しており,左室駆出率の保たれた患者における心不全悪化の高リスク群の検出に有用であることを示すことができた.拡張障害の早期の段階で治療介入をおこなうことで将来の心不全悪化を減らせる可能性がある.
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