Effect of feline obesity and diabetes mellitus on fecal microbiome

2019 Fiscal Year Final Research Report

• Project/Area Number: 17K08112
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Veterinary medical science
• Research Institution: Nippon Veterinary and Life Science University
• Principal Investigator: Toshinori Sako 日本獣医生命科学大学, 獣医学部, 教授 (70153971)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Keywords: マイクロバイオーム / 猫 / 糞便 / 下痢

Outline of Final Research Achievements

Healthy feline fecal microbiomes were investigated using commercial foods of different composition. High-fat and high-fiber diet resulted in specific composition of microbiome. It was also found that a high fiber diet results in a lean intestinal flora. We also investigated whether food containing soluble fiber and prebiotic fiber affect cats with loose stools and diarrhea. The clinical symptoms were significantly improved and the fecal microbiome was also changed. These results are considered to be useful findings for the management of cats with obesity, diabetes mellitus and digestive disorders.

Free Research Field

獣医内分泌学

Academic Significance and Societal Importance of the Research Achievements

本研究は実際に健常猫や疾患を持つ猫に対して、市販のフードを与え、糞便マイクロバイオームや糞便の性状にどのような影響があるかを検討した。結果として、成分の違いにより、糞便マイクロバイオームの組成が異なることや、繊維の添加によって下痢などの症状が改善することが分かった。市販のドライフードを使用しているため、これらの結果はすぐに獣医臨床の現場に還元できるような有用な研究になったと考えられる。