2019 Fiscal Year Final Research Report

Longitudinal study for elucidation of the actual condition of benign thyroid findings

Research Project

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Project/Area Number	17K09088
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Epidemiology and preventive medicine
Research Institution	Nagasaki University
Principal Investigator	HAYASHIDA Naomi 長崎大学, 原爆後障害医療研究所, 教授 (00420638)
Co-Investigator(Kenkyū-buntansha)	前田隆浩長崎大学, 医歯薬学総合研究科(医学系), 教授 (40284674) 山口泉長崎大学, 原爆後障害医療研究所, 客員研究員 (60783660) 中尾麻伊香長崎大学, 原爆後障害医療研究所, 助教 (10749724)
Project Period (FY)	2017-04-01 – 2020-03-31
Keywords	一般成人 / のう胞 / 結節 / 頸動脈超音波検査 / 甲状腺
Outline of Final Research Achievements	In this study, we researched about the frequency of thyroid findings such as thyroid nodule and thyroid cyst. The study participants were residents of Nagasaki prefecture aged 40 years old or more. All participants underwent thyroid ultrasound screening and the size and number of nodules and cysts were recorded. The study population included 4.388 adults (male:1,675, female: 2,713) in all study period. The mean age was 63 years old (male: 65 years, female: 63years). Thyroid cysts were identified in 33.2% and thyroid nodules in 14.1% of participants. The prevalence of thyroid cyst was 33.2%, 29.8%, and 34.6% in 2017, 2018, and 2019, respectively. The prevalence of thyroid nodule was 14.3%, 13.3%, 14.2%, in 2017, 2018, and 2019, respectively. There was no significantly differences between each year. In conclusion, the prevalence of thyroid cyst and nodule in general adults revealed almost 30% and 14%, respectively, in Japan.
Free Research Field	外科学
Academic Significance and Societal Importance of the Research Achievements	福島県における甲状腺検査は、現在のところ、対象者が成人となった後も数十年にわたり続けられる予定である。今後新たに何らかの所見が指摘された対象者は、その原因として考えられる様々な因子を憶測することになる。これまでの研究で、一般成人でも30％がのう胞を、また14％が結節を有していること、さらにはのう胞の存在が甲状腺ホルモンの供給に重要な役割を担う可能性が明らかとなった。今後さらに解析を進め、のう胞や結節に関連する因子が明らかとなれば、現在、そして未来の福島県の甲状腺検査の対象者に、判断材料として重要な情報を与えることができる。