Fundamental research for developing CKD therapy focusing on novel long non-coding RNA

2019 Fiscal Year Final Research Report

• Project/Area Number: 17K09703
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Kidney internal medicine
• Research Institution: Kumamoto University
• Principal Investigator: Morinaga Jun 熊本大学, 病院, 病院教員 (50459210)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Keywords: 長鎖ノンコーディングRNA / 慢性腎臓病

Outline of Final Research Achievements

In order to clarify the role of lnc-RNA-X in the progression of CKD, Jun Morinaga performed animal studies and demonstrated that lnc-RNA-X have favorable effects on some CKD progression. However, further studies are needed to clarify the role of lnc-RNA-X in the progression of CKD.

Free Research Field

慢性腎臓病

Academic Significance and Societal Importance of the Research Achievements

本研究は慢性腎臓病進展においてある長鎖ノンコーディングRNAに着目した研究であるが、本研究の成果は、将来における新たな腎不全治療薬の開発のための重要な手がかりとなる可能性がある。