Establishment and development of optimal physical preventive intervention without drugs or power supply equipment for venous thromboembolism

2019 Fiscal Year Final Research Report

• Project/Area Number: 17K10940
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthopaedic surgery
• Research Institution: Kitasato University
• Principal Investigator: Takahira Naonobu 北里大学, 医療衛生学部, 教授 (70236347)
• Co-Investigator(Kenkyū-buntansha): 坂本 美喜 北里大学, 医療衛生学部, 講師 (40365177)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Keywords: 静脈血栓塞栓症 / 致死的肺血栓塞栓症 / 深部静脈血栓症 / エコノミークラス症候群 / 人工関節置換術合併症 / 理学的予防法 / 静脈血流 / 費用対効果

Outline of Final Research Achievements

Venous thromboembolism is a preventable and fatal disease that has received much attention in society due to its attention in economy class syndrome. It is also one of the major complications in all surgical fields such as artificial joint replacement surgery. However, it has little evidence of effective physical prophylaxis, and current physical prophylaxis only recommends the use of portable, powered intermittent pneumatic devices. We have newly developed a non-powered "deep vein thrombosis preventive device" (this device) and established an optimal physical prevention method for venous thromboembolism without using drugs or power supply devices. As a result, it was found that this method using this device can improve venous blood flow stagnation and can be expected as a safe and effective method.

Free Research Field

静脈血栓塞栓症予防

Academic Significance and Societal Importance of the Research Achievements

今回の研究により、薬剤や電源器具の用意ができない被災地に加えて施設や病院などへ、エビデンスに基づいた新たな最良の理学的予防法による静脈血栓塞栓症の予防法を提供することが可能になります。さらに、費用対効果に優れた方法として臨床応用へと展開することが可能になります。
本法が臨床的に安全性かつ有効性が実証されれば、日本発で世界初の新たな装置の開発・実用化に繋げられ、わが国の産業経済の発展に大きく寄与できます。また、広く致死的肺血栓塞栓症予防への貢献が可能となり、医療安全管理上わが国に大きな利益が得られることが期待できます。