Innovation of mobile traction table and implants for total hip arthroplasty

2020 Fiscal Year Research-status Report

• Project/Area Number: 17K10954
• Research Institution: Chiba University
• Principal Investigator: 中村 順一 千葉大学, 大学院医学研究院, 講師 (80507335)
• Project Period (FY): 2017-04-01 – 2022-03-31
• Keywords: 四肢機能再建学

Outline of Annual Research Achievements

研究（１）については、携帯型下肢牽引手術台の機能で臀部を下から支える三角枕は手術中に大腿骨の操作を行う際に重要な役割を果たすが、患者さんの体格によっては適切な位置に合わせることが難しいため、三角形のクッションの部分をオフセットさせた試作品を開発し、意匠出願（意願2020-026252）した。
研究（３）については、股関節解剖の破格の研究で腸骨関節包筋（Iliocapsular muscle）を解析し英文雑誌に投稿中である。
研究（４）については、人工股関節手術前後の脊椎アライメントを測定し、脊椎の後湾と強直を伴うと後方インピンジメントの原因となり、バランスのとれた脊椎は前方脱臼の原因となり、それぞれ股関節脱臼の危険因子になることを示唆した（Hagiwara S, Nakamura J, et al. Eur Spine J. 2020）。また、骨盤内に突出した臼蓋コンポートの再置換術において、携帯型手術台を用いた仰臥位前方法は血管外科と同一の体位で行うことができ、安全性と効率性が高いことを報告した（He P, Nakamura J, et al. Chiba Med J. 2020）。
研究（６）については、新開発した人工股関節MIRFY（ミルフィー）のインプラントデザインが日本人の骨格構造の83％に適合することについて論文作成中である。
研究（７）については、片側例の変形性股関節症20例のCTデータから有限要素解析を行い、患側と健側を比較したところ、骨折破断強度は患側の方が健側よりも強いことを示した（3,819.5 ± 1,557.8 N 対 3,224.5 ± 943.7 N、P = 0.0405）(Sugano M, Nakamura J, et al. J Biomech. 2020)。

Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

令和２年度の計画は予定通りの成果が出せている。

Strategy for Future Research Activity

令和３年度は研究の最終年度となるため、研究成果の総まとめを行う。具体的には、手術成績の前向きコホート研究の術後5年成績、術中透視によるインプラント設置の精度に関する研究、三次元テンプレートソフトの術後評価の信頼性評価、新規インプラントの力学試験などについて論文発表を行う予定である。

Causes of Carryover

令和２年度は、コロナ禍のため国内外の学会が中止やオンライン開催となり旅費がかからなかったこと、全体として研究費の節約に務めたことから次年度使用額が生じた。
令和３年度は、研究の最終年度となるため、研究成果の総まとめを行う。消耗品として記憶媒体(140)、旅費(210)、謝金(70)、その他(280)、合計額は令和２年度(700)と同額を使用する計画である。前年度の繰越金は主に研究補助に使用する計画である。

Research Products

• [Journal Article] Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus (2021)
  • Author(s): Yin Xianyong、Kim Kwangwoo、Suetsugu Hiroyuki、Bang So-Young、Wen Leilei、Koido Masaru、Ha Eunji、Liu Lu、Sakamoto Yuma、Jo Sungsin、Leng Rui-Xue、Otomo Nao、Laurynenka Viktoryia、Kwon Young-Chang、Sheng Yujun、Sugano Nobuhiko、Nakamura Junichi、et al
  • Journal Title: Annals of the Rheumatic Diseases Volume: 80 Pages: 632～640
  • DOI: 10.1136/annrheumdis-2020-219209
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Japanese Orthopaedic Association 2019 Guidelines for osteonecrosis of the femoral head (2021)
  • Author(s): Ando W, Sakai T, Fukushima W, Kaneuji A, Ueshima K, Yamasaki T, Yamamoto T, Nishii T; Working group for ONFH guidelines, Sugano N.
  • Journal Title: Journal of Orthopaedic Science Volume: 26 Pages: 46～68
  • DOI: 10.1016/j.jos.2020.06.013
  • Peer Reviewed
• [Journal Article] Percutaneously-quantified advanced glycation end-products (AGEs) accumulation associates with low back pain and lower extremity symptoms in middle-aged low back pain patients (2021)
  • Author(s): Umimura T, Orita S, Inage K, Shiga Y, Maki S, Inoue M, Kinoshita H, Norimoto M, Sato T, Sato M, Suzuki M, Enomoto K, Hozumi T, Mizuki N, Takaoka H, Kim G, Nakamura J, et al
  • Journal Title: Journal of Clinical Neuroscience Volume: 84 Pages: 15～22
  • DOI: 10.1016/j.jocn.2020.12.005
  • Peer Reviewed
• [Journal Article] Technical and Conceptual Review on the L5-S1 Oblique Lateral Interbody Fusion Surgery (OLIF51) (2021)
  • Author(s): Orita S, Shiga Y, Inage K, Eguchi Y, Maki S, Furuya T, Aoki Y, Inoue M, Hynes RA, Koda M, Takahashi H, Akazawa T, Nakamura J, et al
  • Journal Title: Spine Surgery and Related Research Volume: 5 Pages: 1～9
  • DOI: 10.22603/ssrr.2020-0086
  • Peer Reviewed
• [Journal Article] Pulmonary Function Improves in Patients with Adolescent Idiopathic Scoliosis who Undergo Posterior Spinal Fusion Regardless of Thoracoplasty: A Mid-Term Follow-Up (2021)
  • Author(s): Akazawa T, Kotani T, Sakuma T, Nakayama K, Iijima Y, Torii Y, Iinuma M, Kuroya S, Asano K, Ueno J, Yoshida A, Murakami K, Minami S, Orita S, Inage K, Shiga Y, Nakamura J, et al
  • Journal Title: Spine Surgery and Related Research Volume: 5 Pages: 22～27
  • DOI: 10.22603/ssrr.2020-0077
  • Peer Reviewed
• [Journal Article] Predictive value of magnetic resonance imaging for multifocal osteonecrosis screening associated with glucocorticoid therapy (2020)
  • Author(s): Nawata Kento、Nakamura Junichi、Hagiwara Shigeo、Wako Yasushi、Miura Michiaki、Kawarai Yuya、Sugano Masahiko、Yoshino Kensuke、Inage Kazuhide、Orita Sumihisa、Ohtori Seiji
  • Journal Title: Modern Rheumatology Volume: 30 Pages: 586～591
  • DOI: 10.1080/14397595.2019.1623363
  • Peer Reviewed
• [Journal Article] Short-term mortality and risk factors associated with reoperation after emergency amputation of the lower limbs (2020)
  • Author(s): Miyamoto Shuichi、Otsuka Makoto、Hasue Fumio、Fujiyoshi Takayuki、Kamiya Koushirou、Kiuchi Hitoshi、Tanaka Tadashi、Nakamura Junichi、Orita Sumihisa、Ohtori Seiji
  • Journal Title: Journal of Orthopaedic Science Volume: 25 Pages: 435～440
  • DOI: 10.1016/j.jos.2019.05.018
  • Peer Reviewed
• [Journal Article] Anatomical course of the lateral femoral cutaneous nerve with special reference to the direct anterior approach to total hip arthroplasty (2020)
  • Author(s): Sugano Masahiko、Nakamura Junichi、Hagiwara Shigeo、Suzuki Takane、Nakajima Takayuki、Orita Sumihisa、Akazawa Tsutomu、Eguchi Yawara、Kawasaki Yohei、Ohtori Seiji
  • Journal Title: Modern Rheumatology Volume: 30 Pages: 752～757
  • DOI: 10.1080/14397595.2019.1637992
  • Peer Reviewed
• [Journal Article] Simultaneous MR neurography and apparent T2 mapping of cervical nerve roots before microendoscopic surgery to treat patient with radiculopathy due to cervical disc herniation: Preliminary results (2020)
  • Author(s): Eguchi Y, Enomoto K, Sato T, Watanabe A, Sakai T, Norimoto M, Yoneyama M, Aoki Y, Suzuki M, Yamanaka H, Tamai H, Kobayashi T, Orita S, Suzuki M, Inage K, Shiga Y, Hirosawa N, Inoue M, Koda M, Furuya T, Nakamura J, et al.
  • Journal Title: Journal of Clinical Neuroscience Volume: 74 Pages: 213～219
  • DOI: 10.1016/j.jocn.2019.08.099
  • Peer Reviewed
• [Journal Article] The 2019 Revised Version of Association Research Circulation Osseous Staging System of Osteonecrosis of the Femoral Head (2020)
  • Author(s): Yoon BH, Mont MA, Koo KH, Chen CH, Cheng EY, Cui Q, Drescher W, Gangji V, Goodman SB, Ha YC, Hernigou P, Hungerford MW, Iorio R, Jo WL, Jones LC, Khanduja V, Kim HKW, Kim SY, Kim TY, Lee HY, Lee MS, Lee YK, Lee YJ, Nakamura J, et al
  • Journal Title: The Journal of Arthroplasty Volume: 35 Pages: 933～940
  • DOI: 10.1016/j.arth.2019.11.029
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Pilot study of oblique lumbar interbody fusion using mobile percutaneous pedicle screw and validation by a three-dimensional finite element assessment (2020)
  • Author(s): Eguchi Y, Orita S, Yamada H, Suzuki M, Yamanaka H, Tamai H, Inage K, Narita M, Shiga Y, Inoue M, Norimoto M, Umimura T, Sato T, Suzuki M, Enomoto K, Koda M, Furuya T, Maki S, Hirosawa N, Aoki Y, Nakamura J, et al
  • Journal Title: Journal of Clinical Neuroscience Volume: 76 Pages: 74～80
  • DOI: 10.1016/j.jocn.2020.04.043
  • Peer Reviewed
• [Journal Article] Postoperative migration of the anatomical and functional anteversion angle following total hip arthroplasty with a well-fixed cemented femoral component with line-to-line implantation (2020)
  • Author(s): Miyamoto Shuichi、Iida Satoshi、Suzuki Chiho、Kawarai Yuya、Nakatani Takushi、Nakamura Junichi、Orita Sumihisa、Ohtori Seiji
  • Journal Title: European Journal of Orthopaedic Surgery & Traumatology Volume: 30 Pages: 1067～1074
  • DOI: 10.1007/s00590-020-02671-w
  • Peer Reviewed
• [Journal Article] Diagnosis of lumbar radiculopathy using simultaneous MR neurography and apparent T2 mapping (2020)
  • Author(s): Sato T, Eguchi Y, Norimoto M, Inoue M, Enomoto K, Watanabe A, Sakai T, Yoneyama M, Aoki Y, Orita S, Narita M, Inage K, Shiga Y, Umimura T, Sato M, Suzuki M, Takaoka H, Mizuki N, Kim G, Hozumi T, Hirosawa N, Furuya T, Maki S, Nakamura J, et al
  • Journal Title: Journal of Clinical Neuroscience Volume: 78 Pages: 339～346
  • DOI: 10.1016/j.jocn.2020.04.072
  • Peer Reviewed
• [Journal Article] Comparison study of bone strength of the proximal femur with and without hip osteoarthritis by computed tomography-based finite element analysis (2020)
  • Author(s): Sugano Masahiko、Hagiwara Shigeo、Nakamura Junichi、Matsuura Yusuke、Suzuki Takane、Wako Yasushi、Miura Michiaki、Kawarai Yuya、Nawata Kento、Yoshino Kensuke、Konno Kenta、Yoh Satoshi、Ohtori Seiji
  • Journal Title: Journal of Biomechanics Volume: 105 Pages: 109810～109810
  • DOI: 10.1016/j.jbiomech.2020.109810
  • Peer Reviewed
• [Journal Article] Unstable AO/OTA type 31-A1.2 intertrochanteric femur fracture: An unusual case report (2020)
  • Author(s): Miyamoto Shuichi、Iida Satoshi、Nakatani Takushi、Yamagata Hiroyuki、Nakamura Junichi、Orita Sumihisa、Ohtori Seiji
  • Journal Title: Trauma Case Reports Volume: 28 Pages: 100326～100326
  • DOI: 10.1016/j.tcr.2020.100326
  • Peer Reviewed
• [Journal Article] Anchor type at upper instrumented vertebra and postoperative shoulder imbalance in patients with Lenke type 1 adolescent idiopathic scoliosis (2020)
  • Author(s): Akazawa T, Kuroya S, Kotani T, Sakuma T, Nakayama K, Iijima Y, Torii Y, Iinuma M, Asano K, Ueno J, Yoshida A, Murakami K, Minami S, Orita S, Inage K, Shiga Y, Nakamura J, et al
  • Journal Title: European Journal of Orthopaedic Surgery & Traumatology Volume: 31 Pages: 245～251
  • DOI: 10.1007/s00590-020-02766-4
  • Peer Reviewed
• [Journal Article] Relationship between Skeletal Muscle Mass, Bone Mineral Density, and Trabecular Bone Score in Osteoporotic Vertebral Compression Fractures (2020)
  • Author(s): Tokeshi Soichiro、Eguchi Yawara、Suzuki Munetaka、Yamanaka Hajime、Tamai Hiroshi、Orita Sumihisa、Inage Kazuhide、Shiga Yasuhiro、Hagiwara Shigeo、Nakamura Junichi、Akazawa Tsutomu、Takahashi Hiroshi、Ohtori Seiji
  • Journal Title: Asian Spine Journal Volume: － Pages: －
  • DOI: 10.31616/asj.2020.0045
  • Peer Reviewed
• [Journal Article] Impact of spinal alignment and stiffness on impingement after total hip arthroplasty: a radiographic study of pre- and post-operative spinopelvic alignment (2020)
  • Author(s): Hagiwara Shigeo、Orita Sumihisa、Nakamura Junichi、Inage Kazuhide、Kawasaki Yohei、Shiko Yuki、Eguchi Yawara、Ohtori Seiji
  • Journal Title: European Spine Journal Volume: － Pages: －
  • DOI: 10.1007/s00586-020-06589-z
  • Peer Reviewed
• [Journal Article] Myovascular Preserving Open-Door Laminoplasty for Cervical Spondylotic Myelopathy With Miniplate Fixation (2020)
  • Author(s): Eguchi Y, Suzuki M, Yamanaka H, Tamai H, Kobayashi T, Orita S, Narita M, Inage K, Kanamoto H, Abe K, Inoue M, Norimoto M, Umimura T, Sato T, Aoki Y, Watanabe A, Koda M, Furuya T, Nakamura J, et al
  • Journal Title: International Journal of Spine Surgery Volume: 14 Pages: 476～482
  • DOI: 10.14444/7062
  • Peer Reviewed
• [Journal Article] Natural history of noise and squeaking in cementless ceramic-on-ceramic total hip arthroplasty (2020)
  • Author(s): Inagaki Kenta、Iida Satoshi、Miyamoto Shuichi、Suzuki Chiho、Nakatani Takushi、Shinada Yoshiyuki、Kawarai Yuya、Hagiwara Shigeo、Nakamura Junichi、Orita Sumihisa、Ohtori Seiji
  • Journal Title: Journal of Orthopaedics Volume: 21 Pages: 544～549
  • DOI: 10.1016/j.jor.2020.09.009
  • Peer Reviewed
• [Journal Article] Minimum 5 year follow-up of clinical and radiographic results of cemented acetabular components with an interface bioactive bone cement technique in primary cemented total hip arthroplasty (2020)
  • Author(s): Miyamoto Shuichi、Iida Satoshi、Suzuki Chiho、Nakatani Takushi、Kawarai Yuya、Nakamura Junichi、Orita Sumihisa、Ohtori Seiji
  • Journal Title: Archives of Orthopaedic and Trauma Surgery Volume: 141 Pages: 139～147
  • DOI: 10.1007/s00402-020-03638-6
  • Peer Reviewed
• [Journal Article] Frequency of Adverse Drug Reactions and Analgesic Effects of Mirogabalin during Treatment of Peripheral Neuropathic Pain: A Retrospective Clinical Investigation (2020)
  • Author(s): Inage K, Sainoh T, Fujiyoshi T, Otagiri T, Aoki Y, Inoue M, Eguchi Y, Orita S, Shiga Y, Koda M, Akazawa T, Furuya T, Nakamura J, et al
  • Journal Title: Spine Surgery and Related Research Volume: 4 Pages: 354～357
  • DOI: 10.22603/ssrr.2020-0042
  • Peer Reviewed
• [Journal Article] Treatment of protrusion of the acetabular component after total hip arthroplasty in combination with vascular surgery: a report of three cases. (2020)
  • Author(s): He P, , Yoshino K, Hagiwara S, Nakamura J, Ueda H, Kawarai Y, Sugano M, Nawata K, Konno K, Yoh S, Matsumiya G, Ohtori S.
  • Journal Title: Chiba Medical J. Volume: 96E Pages: 59～65
  • DOI: 10.20776/S03035476-96E-3-P59
  • Peer Reviewed / Open Access
• [Presentation] 当科における関節リウマチ治療の現状：2016年 (2020)
  • Author(s): 中村 順一、萩原 茂生
  • Organizer: 第49回日本リウマチの外科学会
• [Presentation] 整形外科目線からみたリウマチ治療のunmet needs-JAK阻害薬とBio- (2020)
  • Author(s): 中村 順一
  • Organizer: 第25回東葛関節研究会
• [Presentation] 関節リウマチにおけるアバタセプトの骨破壊抑制 (2020)
  • Author(s): 中村 順一
  • Organizer: オレンシアインターネットシンポジウム
  • Invited
• [Presentation] DAA（Direct Anterior Approach）アプローチ～若手が知っておくべきピットフォール～牽引手術台による手術支援 (2020)
  • Author(s): 中村 順一
  • Organizer: 第61回関東整形災害外科学会
• [Patent(Industrial Property Rights)] 下肢牽引装置におけるヒップピロー設置台 (2020)
  • Inventor(s): 萩原茂生、中村順一、川崎善之、谷村雅人、大石泰史
  • Industrial Property Rights Holder: 萩原茂生、中村順一、川崎善之、谷村雅人、大石泰史
  • Industrial Property Rights Type: 意匠
  • Industrial Property Number: 意願2020-26252