2021 Fiscal Year Final Research Report
Development of a system for predicting the risk of onset and severity of obstructive sleep apnea through orthodontic and respiratory medicine collaboration
| Project/Area Number |
17K12042
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Social dentistry
|
|---|
| Research Institution | Niigata University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
丹原 惇 新潟大学, 医歯学系, 講師 (10636228)
高橋 功次朗 新潟大学, 医歯学総合病院, 助教 (40736625)
齋藤 功 新潟大学, 医歯学系, 教授 (90205633)
|
|---|
| Project Period (FY) |
2017-04-01 – 2022-03-31
|
| Keywords | 閉塞性睡眠時無呼吸 / Polysomnography / 側面セファログラム / 性別 / 年代別 |
|---|
| Outline of Final Research Achievements |
In the present study, we analyzed the clinical characteristics of OSA in Japanese adult OSA patients by sex and age with a focus on maxillofacial morphology and BMI. The results indicated that the clinical features of OSA vary between men and women and between different age groups, and suggest that factors such as the vertical position of the hyoid bone and the cross-sectional area of the tongue may have a greater effect than the position of the jawbone on the severity of OSA.
In addition, our results suggest that OSA in female patients is possibly affected by factors other than maxillofacial morphology and BMI, and that female hormone tests should be included in OSA-related parameters in the case of females.
|
| Free Research Field |
歯科矯正学
|
| Academic Significance and Societal Importance of the Research Achievements |
OSAに対する現在の治療および検査体系はおもに男性患者を主体に確立したものであるが、今回の結果から、男女間、さらに年代間でもOSAの病態は異なっていることが示され、今後OSAに対する治療については、性別や年代による要因の差に配慮した検査方法や治療法を模索する必要がある。
今回の研究結果から舌骨の低位がOSAの重症化に関与することが示されたことは、今後、舌骨や舌が低位であるOSA患者に対してContinuous positive airway pressureや口腔内装置などの標準的な治療法に加えMyofunctional therapyを適用する根拠となる。
|
