Quality control of biobanks and construction of a personal health care prediction system using this information

2022 Fiscal Year Final Research Report

• Project/Area Number: 17K13211
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Applied health science
• Research Institution: Fujita Health University (2020-2022); Gihu University of Medical Science (2017-2019)
• Principal Investigator: Takeda Mayu 藤田医科大学, 医学部, 講師 (00423054)
• Project Period (FY): 2017-04-01 – 2023-03-31
• Keywords: バイオバンク

Outline of Final Research Achievements

The effect of storage conditions on the variation of measurements (comparison of initial test results and measurements of stored bioresources (BRs)) caused by the number of years that BRs have been stored in a biobank was investigated. The results indicated that even for BRs that had been in storage for 10 years, no items fluctuated significantly, suggesting that the BRs were stored in a stable condition. The database system at the Resource Center for Health Science (RECHS) was also examined to increase the volume of information in the system as a whole and to automate information entry. As a result, it became possible to obtain information on personal health more easily.

Free Research Field

臨床検査学

Academic Significance and Societal Importance of the Research Achievements

これからの健康診断においては、発症前に高い精度で発症予測を行い、予見的に介入することで発症を防止するという先制医療の実施を目指している。発症予測の可能なバイオマーカーはこれから需要が高まる一方であるが、その臨床的有用性や妥当性について検証を目的としたバイオリソース（BR） は必要不可欠であると考えられる。被検者の協力により、発症前のBRを暦年的にバンキングすることによって、得られる情報価値は高い。一方で、品質を落とすことなくBRを活用することで正しい研究成果につながるため、BRの保管年数と品質に関する検討とその結果においては意義あるものと考えられる。