Development of innovative radiotherapy support system with predictable prognosis in head and neck cancer

2019 Fiscal Year Final Research Report

• Project/Area Number: 17K15808
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Medical Physics and Radiological Technology
• Research Institution: Teikyo University
• Principal Investigator: Kamezawa Hidemi 帝京大学, 福岡医療技術学部, 講師 (50759503)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Keywords: 頭頸部癌 / 予後予測 / 生存率 / 悪性度 / radiomics

Outline of Final Research Achievements

The purpose of this study was to develop an innovative radiotherapy support system with predictable prognosis in head and neck cancer. We could predict the 2-year survival of squamous cell head and neck cancer and malignancy glade of parotid gland cancer by using some machine learning approaches. Therefore, we could develop an innovative radiotherapy support system for squamous cell head and neck cancer and parotid gland cancer.
The proposed approach could support the decision making of the radiotherapy approach for the low 2-year survival squamous cell head and neck cancer and high glade parotid gland cancer.

Free Research Field

医学物理学

Academic Significance and Societal Importance of the Research Achievements

本研究で開発した放射線治療支援システムは、治療前にあらかじめ扁平上皮頭頸部癌の２年生存率や高悪性度の耳下腺癌を予測できるため、それらの癌に最適な治療方針を検討する上で有用である。また、医用画像のみの入力で予測が可能であるため、非侵襲的であることは医学的意義も大きい。
さらには、頭頸部癌のみならず、他部位のさまざまな癌においても応用出来る可能性を持っており、波及効果も高いと考える。