Cost effectiveness analysis for multi-factorial intervention for elderly inpatients with delirium

2019 Fiscal Year Annual Research Report

• Project/Area Number: 17K15905
• Research Institution: St. Luke's International University
• Principal Investigator: 大出 幸子 聖路加国際大学, 専門職大学院公衆衛生学研究科(公衆衛生大学院), 准教授 (80505074)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Keywords: 費用対効果分析 / せん妄

Outline of Annual Research Achievements

Introduction: Delirium is a condition which often are seen in elderly inpatients. It causes complicated symptoms such as confusion and agitation that provide a lot of burden to patients, health providers and patients’ family. There are several randomized controlled studies of multifactorial intervention which enable early recover from delirium but its cost-effectiveness is still uncertain.
Objective: To assess cost-effectiveness for our multifactorial intervention towards delirium remission, using real-world data. Method: We have implemented three multifactorial intervention at St. Luke’s International Hospital form 2017-2018, which includes 1）team round by specialists of psychosomatic internists and nurse practitioners, 2）establishment of prescription monitoring and 3）Providing rehabilitation program by occupational therapists. We used a real world data to investigate its cost-effectiveness, utilizing Markov model. Result: the multi-factorial intervention was cost-effective when compared to historical data without implementation of interventions. It was associated with ICER of £30,546 using a cost-effectiveness threshold of £50,000 per quality-adjusted life year (QALY). Conclusion: Our real-world data analysis has shown that multi-factorial intervention for delirium was cost-effective among elderly inpatients. Medical health care providers should consider to apply this strategy as a standard care when elderly inpatients caused a delirium complication.

Research Products

• [Presentation] Cost effectiveness analysis for multi-factorial intervention for elderly inpatients with delirium (2019)
  • Author(s): Ohde S, Takekata M, Takiguchi M, Namiki C , Abe K, Nishizawa S, Tanaka M, Saito N, Yamada U, Kajima N, Masui N, Takahashi O.
  • Organizer: International Society for Pharmacoeconomics and Outcomes
  • Int'l Joint Research