Development of pumping emulsification device to form lipiodol emulsion in transarterial chemoembolization for HCC

2018 Fiscal Year Final Research Report

• Project/Area Number: 17K16474
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Nara Medical University
• Principal Investigator: Masada Tetsuya 奈良県立医科大学, 医学部, 助教 (60727593)
• Project Period (FY): 2017-04-01 – 2019-03-31
• Keywords: VX2腫瘍 / TACE / リピオドール / エマルション

Outline of Final Research Achievements

In our in vivo study, histopathological findings of transarterial chemoembolization (TACE) using the pumping emulsification device were evaluated in a rabbit VX2 liver tumor model. As a result of our in vivo study, the pumping emulsification device can achieve stronger antitumor effects compared with the current standard technique using three-way cock.

Free Research Field

Interventional Radiology

Academic Significance and Societal Importance of the Research Achievements

肝細胞癌に対する肝動脈化学塞栓療法（TACE）における新規W/Oエマルションの作成を行った。抗腫瘍効果において従来法より効果的なエマルションの開発により、再発・進行肝細胞癌に対するTACEの治療成績向上に寄与することが期待できる。