2021 Fiscal Year Annual Research Report
Association between adverse events and physical function or cognitive function in older patients with peritoneal dialysis.
| Project/Area Number |
17K17522
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| Research Institution | Seirei Christopher University |
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Principal Investigator |
矢部 広樹 聖隷クリストファー大学, リハビリテーション学部, 准教授 (40780664)
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| Project Period (FY) |
2017-04-01 – 2022-03-31
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| Keywords | 腹膜透析 / 高齢者 / 予後 / 軽度認知障害 / 出口部感染 |
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| Outline of Annual Research Achievements |
Background: Elderly peritoneal dialysis (PD) patients required assistance for a variety of PD-related tasks. The usefulness of assisted PD in reducing the peritonitis risk has been reported.
Methods: This was a single-center, prospective cohort study. Thirty-three patients (mean age: 74.8 years) on PD were evaluated for cognitive impairment (CI) using the Japanese version of the Montreal Cognitive Assessment. They were also evaluated to determine whether they performed the exit-site care procedure alone or with assistance. Patients were categorized into four groups based on the presence or absence of CI and the presence or absence of exit-site care assistance. They were followed up until the occurrence of peritonitis and exit-site infection at the end of the follow-up.
Results: Altogether, 8, 8, and 17 patients were assigned to the “without CI and without assistance”, “without CI and with assistance”, and “with CI and with assistance groups”, respectively; no patients were assigned to the “with CI and without assistance group”. Six and 16 patients experienced peritonitis and exit-site infection during follow-up, respectively. Kaplan–Meier analysis and log-rank tests revealed that the “without CI and without assistance group” was significantly associated with exit-site infection (log-rank < 0.05).
Conclusion: Patients who did not receive assistance for exit-site care were at a higher risk of exit-site infections, even in the absence of CI. Caregiver assistance is important for preventing exit-site infections in older patients on PD.
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