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2019 Fiscal Year Annual Research Report

Development of High-Accuracy Tumor Tracking Systems for Next-Generation Radi ation Therapy Technology

Research Project

Project/Area Number 17K17582
Research InstitutionSendai National College of Technology

Principal Investigator

張 暁勇  仙台高等専門学校, 総合工学科, 助教 (90722752)

Project Period (FY) 2017-04-01 – 2020-03-31
KeywordsRadiation therapy / Tumor tracking / Hidden Markov model
Outline of Annual Research Achievements

The purpose of this research is to develop a markerless tracking system for image-guided radiation therapy. The tracking system is capable of tracking the respiration-induced tumor motion automatically in real-time during radiation delivery, and will be able to provide conformable tumor motion information and to allow the treatment device to deliver high-dose conformable radiation to the moving target accurately.
According to the research plan, the research achievements in the FY2019 are summarized as follows. (1) Several thorax phantom-based experiments have been conducted at Tohoku university hospital and sets of kilo-voltage (kV) images data and megavoltage (MV) image data have been acquired for evaluation of tumor tracking system; (2) Extensive experiments have been conducted to evaluate the previous proposed tracking methods and compared with existing tracking methods; (3) A papers, which focused on extracting the tumor from X-ray images for accurate tracking, has been published in IEEJ transactions on electronics, information and system (電気学会論文誌C); (4) A Japanese patent (特許第6524497) and a United States patent (No. US10,504,225 B2) have been registered. (5) Several preliminary studies that utilize the deep learning techniques to extract the tumor from X-ray images have been conducted, and the experimental results demonstrated a promising perspective of the deep learning for radiation therapy.

  • Research Products

    (6 results)

All 2020 2019 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (4 results) (of which Int'l Joint Research: 1 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Journal Article] Hidden Markov Model-based Extraction of Target Objects in X-ray Image Sequence for Lung Radiation Therapy2020

    • Author(s)
      Shindo Masahiro、Ichiji Kei、Homma Noriyasu、Zhang Xiaoyong、Okuda Shungo、Sugita Norihiro、Yamaki Shunsuke、Takai Yoshihiro、Yoshizawa Makoto
    • Journal Title

      IEEJ Transactions on Electronics, Information and Systems

      Volume: 140 Pages: 49~60

    • DOI

      10.1541/ieejeiss.140.49

    • Peer Reviewed
  • [Presentation] A Comparison Study of Deep Learning Techniques for Mass Detection in Mammograms2019

    • Author(s)
      K. Noro, Xiaoyong. Zhang, H. Takano, K. Ichiji, N. Homma
    • Organizer
      2019 AAPM Annual Meeting
    • Int'l Joint Research
  • [Presentation] Risk Analysis of Bilateral Mammographic Density Differences for Breast Cancer: A Case-Control Study2019

    • Author(s)
      Jiaqi Chen, Xiaoyong Zhang, Tadashi Ishibashi, Yumi Takane, Satoru Yanagaki, Daisuke Shibuya, Kei Ichiji, Makoto Osanai, Noriyasu Homma
    • Organizer
      第27回日本乳癌学会学術総会
  • [Presentation] Deep Learning for Drowning Diagnosis using Post-mortem Lung CT Images2019

    • Author(s)
      本間経康, 佐藤亮太, 張暁勇, 今野拓也, Amber Qureshi, 市地慶, 臼井彰人, 川住祐介, 舟山眞人
    • Organizer
      SICE システム・情報部門 知能工学部会 第47回知能システムシンポジウム
  • [Presentation] 4次元CT補間に基づく隠れマルコフモデルを用いたX線動画像中の腫瘍像描出能 向上2019

    • Author(s)
      奥田隼梧,市地慶,本間経康,張曉勇, 吉澤誠
    • Organizer
      計測自動制御学会東北支部 55 周年記念学術講演会
  • [Patent(Industrial Property Rights)] Image processing device, image processing method, and non-transitory computer-readable recording medium having stored therein image processing program2017

    • Inventor(s)
      本間経康、酒井正夫、市地慶、渋澤直樹、張暁勇、その他
    • Industrial Property Rights Holder
      東北大学、弘前大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      10504225 B2
    • Overseas

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Published: 2021-01-27  

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