New strategy of therapeutic dialysis care with Belt electrode skeletal muscle electrical stimulation.

2019 Fiscal Year Final Research Report

• Project/Area Number: 17K18050
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering; Clinical nursing
• Research Institution: Dokkyo Medical University
• Principal Investigator: Tamura Yuma 獨協医科大学, 医学部, 研究員 (60727585)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Keywords: 腎臓リハビリテーション / 骨格筋電気刺激 / 透析療法

Outline of Final Research Achievements

In this study is investigate therapeutic dialysis care by the B-SES to suppress blood glucose elevation and improve skeletal muscle function in dialysis patients with diabetic nephropathy. subjects were 11 patients with end-stage diabetic kidney disease undergoing hemodialysis.
【Acute effect】As a result of taking supplemental nutrition during dialysis and then performing B-SES, suppression of blood glucose elevation and improvement in the average blood glucose fluctuation range 24 hours after dialysis were observed.
【Continuous effect for 3 months】In some cases, B-SES improved blood glucose control and skeletal muscle function. It was suggested that B-SES during dialysis may be useful for improving skeletal muscle function and glucose tolerance.

Free Research Field

腎臓リハビリテーション

Academic Significance and Societal Importance of the Research Achievements

糖尿病性腎症による透析患者は透析起因性高血糖のリスクを有し、厳格な血糖コントロールが必要となる。さらに平均血糖変動幅が3.9mmol/dlを超える患者では心疾患リスクが上昇する。本研究の介入により、血糖上昇や24時間の血糖変動の改善を認め、透析起因性高血糖の是正に加え、心疾患リスクの軽減に寄与する可能性を示した。また、3ヶ月間のB-SESの実施により血糖コントロールや骨格筋機能の改善を一部の患者群で認めた。
透析中のB-SES実施は非薬物療法として効果を認め、新たな透析治療の一助となった。