2018 Fiscal Year Research-status Report
Analyses of the Synergy of Sub/Supercritical H2O-CO2 System for Synthesis of Green Platform Chemicals
| Project/Area Number |
17KK0118
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| Research Institution | Kumamoto University |
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Principal Investigator |
キタイン アルマンド 熊本大学, グローバル教育カレッジ, 教授 (50504693)
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| Project Period (FY) |
2018 – 2020
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| Keywords | hydrolysis / supercritical CO2 / subcritical H2O / Raman spectroscopy / functionalization / CO2 reduction / 5-HMF / glycosidic bond |
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| Outline of Annual Research Achievements |
In-situ monitoring of the reaction taking place during hydrolysis of hesperidin under supercritical CO2-subcritical H2O system was carried out by Raman spectroscopy using the high temperature and high pressure sapphire view cell at Valladolid University. Two graduate students was also attached to this university to help monitor the reaction mechanisms involving the hydrolysis of the glycosidic bond linking the sugar moieties and aglycone, and the conversion of the obtained sugar into 5-HMF.Results of Raman spectroscopy indicated the presence of superacidic interfacial layer between the supercritical CO2 phase and subcritical H2O phase, which could explain the reason for the relatively higher yield of hesperetin compared to the conventional method.The analysis of molecular orientation of hesperidin between the two phases is currently on going.
I also visited Prof. Anke Krueger Group of Wurzburg University with two graduate students - one worked on various analyses of functionalized nanodiamond using various approaches such as supercritical H2O, CO2 and NH3 carried out at Kumamoto University. The other student learned P and B functionalization of carbon materials, which will be used in succeeding experiments including carbon dioxide reduction into useful chemicals.
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| Current Status of Research Progress |
Current Status of Research Progress
1: Research has progressed more than it was originally planned.
Reason
A new research collaboration with the Bioinformatics and High Performance Computing Research Group of Prof. Horacio Sanchez of Universidad Catolica San Antonio de Murcia (Spain) has been established to elucidate the mechanism of the hydrolysis by molecular dynamic simulation to support the data obtained by Raman spectroscopy.To encourage student mobility and development of young researchers, 4 graduate students have also been dispatched to work on the project. Two students were supported by the TOBITATE Ryugaku JAPAN Program.Also, another PhD student from the Philippines joined Kumamoto University to work on the application of the proposed supercritical CO2-H2O synergy to extraction of natural compounds, and the results have been submitted for publication in the Journal of Supercritical Fluids.
Also, a memorandum of understanding (MOU) for research collaboration and student exchanges between Kumamoto University and Valladolid University (Spain) and Wurzburg University (Germany) has been signed. This MOU will foster active research collaboration and students exchanges with the two top European universities. Prof. Maria Jose Cocero has also been invited as an International Research Organization for Advanced Science and Technology (IROAST) Visiting Professor to further enhance research collaboration between the 2 universities.
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| Strategy for Future Research Activity |
The conversion of the obtained sugar (glucose) from hesperidin into bioenergy platform chemicals such as 5-HMF will be further elucidated and analyzed in collaboration with Prof. MJ Cocero (Valladolid University). Furthermore,the functionalized carbon materials (nanodiamond and reduced graphene oxide) will be used for the reduction of CO2 using the novel hydrothermal CO2 reduction process.The application will be extended to catalytic hydrothermal conversion of CO2 into useful chemicals or fuels by our novel reactive separation approach. Catalytic reduction of CO2 under hydrothermal conditions into useful compounds such as carboxylic acids and alcohol will be elucidated using the developed catalysts.
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Research Products
(7 results)
