カーボンナノケージ空間のバイオ・超分子分野への応用

2006 Fiscal Year Annual Research Report

• Project/Area Number: 18033059
• Research Institution: National Institute for Materials Science
• Principal Investigator: 有賀 克彦 独立行政法人物質・材料研究機構, ナノ有機センター, グループリーダー (50193082)
• Co-Investigator(Kenkyū-buntansha): VINU Ajayan 独立行政法人物質・材料研究機構, 燃料電池材料センター, 主任研究員 (50421425)
• Keywords: ナノ構造 / 超分子化学 / 環境 / 生体材料 / 反応・分離工学

Research Abstract

カーボンナノケージ作製においては、鋳型としてケージ型のメソポーラスシリカKIT-5を用いることにより、入り組んだケージ構造のメソポーラスカーボンが得る。具体的には、炭素源であるショ糖を鋳型であるシリカ構造に封入し、熱処理による重合化と炭化のプロセスを経て、最終的にフッ化水素酸でシリカ部分を選択的に溶出することによってカーボンナノケージを合成した。カーボンナノケージの詳細構造を高解像度の透過型電子顕微鏡(HRTEM)観察によって検討したところ、高い規則性の孔構造が確かめられた。窒素吸着・脱着挙動より、平均孔径は5.2nmであり、広い部分のケージ径は15.0nmとなることがわかった。作製条件を変化させ検討し最適伸されたカーボンナノケージの比表面積および比孔容積の値は、それぞれ1600m^2g^<-1>および2.10cm^3g^<-1>であり、代表的なメソポーラスカーボンCMK-3の値(比表面積1260m^2g^<-1>および比孔容積1.1cm^3g^<-1>)や合成温度を変えて改質した鋳型を用いて作製したCMK-3の値(比表面積1350m^2g^<-1>および比孔容積1.6cm^3g^<-1>)をはるかに凌ぐことがわかった。カーボンナノケージに対する様々な生理活性物質の吸着を検討した結果、活性炭やCMK-3などに比べて非常に高い吸着能を示し、ヒスチジンなどのアミノ酸、カテキンなどのフラボノイド、α-トコフェロール(ビタミンE)などのビタミシ等の有用物質の抽出回収や、ノニルフェノールなどの内分泌かく乱物質等の有害物質の除去に優れた能力を示すことが明らかとなった。カーボンナノケージは、タンパク質などの大きな生体物質の吸着にも有利である。リゾチームの吸着挙動は、従来の炭素物質を大きくしのぎ、26.5μmol/gという値が得られた。

Research Products

• [Journal Article] Lysozyme Adsorption onto Mesoporous Materials : Effect of Pore Geometry and Stability of Adsorbents (2007)
  • Author(s): Vinu, Ajayan, Miyahara, Masahiko, Hossain, Kazi Zakir, Takahashi, Motoi, Balasubramanian, Veerappan Vaithilingam, Mori, Toshiyuki, Ariga, Katsuhiko
  • Journal Title: J. Nanosci. Nanotechnol. 7(3) Pages: 828-832
• [Journal Article] Catalysis of a Peptidic Micellar Assembly Covalently Immobilized within Mesoporous Silica Channels : Importance of Amphiphilic Spatial Design (2007)
  • Author(s): Otani, Wataru, Kinbara, Kazushi, Zhang, Qingmin, Ariga, Katsuhiko, Aida, Takuzo
  • Journal Title: Chem. Eur. J. 13(6) Pages: 1731-1736
• [Journal Article] Adsorption Myoglobin over Mesoporous Silica Molecular Sieves : Pore Size Effect and Pore-Filling Model (2007)
  • Author(s): Miyahara, Masahiko, Vinu, Ajayan, Ariga, Katsuhiko
  • Journal Title: Mater. Sci. Eng. C 27(2) Pages: 232-236
• [Journal Article] Controlling the Textural Parameters of Mesoporous Carbon Materials (2007)
  • Author(s): Vinu, A., Srinivasu, P., Takahashi, M., T.Mori, T., Balasubramanian, V.V., Ariga, K.
  • Journal Title: Microporous Mesoporous Mater. 100(1-3) Pages: 20-26
• [Journal Article] Halogen-Free Acylation of Toluene over FeSBA-1 Molecular Sieves (2007)
  • Author(s): Vinu, A., Krithiga, T., Gokulakrishnan, N., Srinivasua, P., Anandana, S., Ariga, K., Murugesan, V., Balasubramaniand, V.V., Mori, T.
  • Journal Title: Microporous Mesoporous Mater. 100(1-3) Pages: 87-94
• [Journal Article] Mesoporous Nitrides through Nano-Hard Templating Techniches (2007)
  • Author(s): Vinu, Ajayan, Anandan, Srinivasan, Gokulakrishnan, Narasimhan, Srinivasu, Pavuluri, Mori, Toshiyuki, Ariga, Katsuhiko
  • Journal Title: Solid State Phenom. 119 Pages: 291-294
• [Journal Article] Photocatalytic Activity of La-Doped ZnO for the Degradation of Monocrotophos in Aqueous Suspension (2007)
  • Author(s): Anandan, S., Vinu, A., Sheeja Lovely, K.P.L., Gokulakrishnan, N., Srinivasu, P., Mori, T., Murugesan, V., Sivamurugan, V., Ariga, K.
  • Journal Title: J. Mol. Catal. A-Chem. 266(1-2) Pages: 149-157
• [Journal Article] Adsorption of L-Histidine over Mesoporous Carbon Molecular Sieves (2006)
  • Author(s): Vinu, A., Hossain, K.Z., Satish Kumar, G., Ariga, K.
  • Journal Title: Carbon 44(3) Pages: 530-536
• [Journal Article] Preparation and Catalytic Performances of Ultra Large Pore TiSBA-15 Mesoporous Molecular Sieves with Very High Ti Content (2006)
  • Author(s): Vinu, A., Srinivasu, P., Miyahara, M., Ariga, K.
  • Journal Title: J. Phys. Chem. B. 110(2) Pages: 801-806
• [Journal Article] A Novel Bis Zinc Porphyrin-Oxoporphyrinogen Donor-Acceptor Triad : Synthesis, Electrochemical, Computational and Photochemical Studies (2006)
  • Author(s): Hill, Jonathan P., Sandanayaka, Atula S.D., McCarty, Amy Lea, Karr, Paul A., Zandler, Melvin E., Charvet, Richard, Ariga, Katsuhiko, Araki, Yasuyuki, Ito, Osamu, D'Souza, Francis
  • Journal Title: Eur. J. Org. Chem. (3) Pages: 595-603
• [Journal Article] Adsorption Study of Heme-Proteins on SBA-15 Mesoporous Silica with Pore-Filling Models (2006)
  • Author(s): Miyahara, Masahiko, Vinu, Ajayan, Hossain, Kazi Zakir, Nakanishi, Takashi, Ariga, Katsuhiko
  • Journal Title: Thin Solid Films 499(1-2) Pages: 13-18
• [Journal Article] ナノ素材「フラーレン」の形を自在に変える (2006)
  • Author(s): 中西尚志, 有賀克彦
  • Journal Title: Science ＆ Technology Journal 15(2) Pages: 30-31
• [Journal Article] Regulation of Film Electrochemistry and CO Binding of a Diruthenium Complex Embedded in Artificial Lipids on an Electrode (2006)
  • Author(s): Nakanishi, Takashi, Ariga, Katsuhiko, Thuriere, Antoine, Bear, John L., Kadish, Karl M.
  • Journal Title: Thin Solid Films 499(1-2) Pages: 349-353
• [Journal Article] Control of Morphology and Helicity of Chiral Mesoporous Silica (2006)
  • Author(s): Jin, Haiying, Liu, Zheng, Ohsuna, Tetsu, Terasaki, Osamu, Inoue, Yoshihisa, Sakamoto, Kazutami, Nakanishi, Takashi, Ariga, Katsuhiko, Che, Shunai
  • Journal Title: Adv. Mater. 18(5) Pages: 593-596
• [Journal Article] Perfectly Straight Nanowires of Fullerenes Bearing Long Alkyl-Chains on Graphite (2006)
  • Author(s): Nakanishi, Takashi, Miyashita, Naoko, Michinobu, Tsuyoshi, Wakayama, Yutaka, Tsuruoka, Tohru, Ariga, Katsuhiko, Kurth, Dirk G.
  • Journal Title: J. Am. Chem. Soc. 128(19) Pages: 6328-6329
• [Journal Article] A Paradigm Shift in the Field of Molecular Recognition at the Air-Water Interface : from Static to Dynamic (2006)
  • Author(s): Ariga, Katsuhiko, Nakanishi, Takashi, Hill, Jonathan P.
  • Journal Title: Soft Matter 2(6) Pages: 465-477
• [Journal Article] Regulating the stability of 2D crystal structures using an oxidation state-dependent molecular conformation (2006)
  • Author(s): Hill, Jonathan P., Wakayama, Yutaka, Schmitt, Wolfgang, Tsuruoka, Tohru, Nakanishi, Takashi, Zandler, Melvin L., McCarty, Amy L., D'Souza, Francis, Milgrom, Lionel R., Ariga, Katsuhiko
  • Journal Title: Chem. Commun. (22) Pages: 2320-2322
• [Journal Article] Carbon nanocage : a large pore cage-type mesoporous carbon material as an adsorbent for biomolecules (2006)
  • Author(s): Vinu, Ajayan, Miyahara, Masahiko, Mori, Toshiyuki, Ariga, Katsuhiko
  • Journal Title: J. Porous Mater. 13(3) Pages: 379-383
• [Journal Article] 超分子的手法によるフラーレンのナノ・マイクロ加工技術-燃料電池素材に向けて- (2006)
  • Author(s): 中西尚志, 有賀克彦
  • Journal Title: 月刊ディスプレイ 12(6) Pages: 67-71
• [Journal Article] Assemblies of Biomaterials in Mesoporous Media (2006)
  • Author(s): Vinu, Ajayan, Miyahara, Masahiko, Ariga, Katsuhiko
  • Journal Title: J. Nanosci. Nanotechnol 6(6) Pages: 1510-1532
• [Journal Article] Remarkable Difference of Phase Transition Behaviors between Langmuir Monolayers and Aqueous Bilayer Vesicles of Olieopeptide-Carrying lipids (2006)
  • Author(s): Ariga, Katsuhiko, Nakanishi, Takashi, Kawanami, Shin-ichi, Kosaka, Takatoshi, Kikuchi, Jun-ichi
  • Journal Title: J. Nanosci. Nanotechnol. 6(6) Pages: 1718-1730
• [Journal Article] Immobilization of Lysozyme onto Pore-Engineered Mesoporous AlSBA-15 (2006)
  • Author(s): Miyahara, Miyahara, Vinu, Ajayan, Ariga, Katsuhiko
  • Journal Title: J. Nanosci. Nanotechnol. 6(6) Pages: 1765-1771
• [Journal Article] Construction and Electrochemistry of Langmuir-Blodgett Films of Fullerene Lipid Composite/Hybrid Materials (2006)
  • Author(s): Nakanishi, Takashi, Kouzai, Hidetoshi, Morita, Makoto, Murakami, Hiroto, Sagara, Fakamasa, Ariga, Katsuhiko, Nakashima, Naotoshi
  • Journal Title: J. Nanosci. Nanotechnol. 6(6) Pages: 1779-1785
• [Journal Article] Two-Dimensional Molecular Patterns and Their Dynamic Functions : Molecular Recognition of Aqueous Guest by Mixed Monolayer of Alkyl Cyclophane and Amphiphilic Guanidinium (2006)
  • Author(s): Ariga, Katsuhiko, Nakanishi, Takashi, Takagi, Naoko, Tanaka, Ryutaro, Kikuchi, Jun-ichi
  • Journal Title: Colloid Surf. A-Physicochem. Eng. Asp. 284/285 Pages: 499-504
• [Journal Article] Electrochemistry of Fullerene C_<60> Embedded in Langmuir-Blodgett Films of Artificial Lipids on Electrodes (2006)
  • Author(s): Nakanishi, Takashi, Ariga, Katsuhiko, Morita, Makoto, Kozai, Hideaki, Taniguchi, Naoya, Murakami, Hiroto, Sagara, Takamasa, Nakashima, Naotoshi
  • Journal Title: Colloid Surf. A-Physicochem. Eng. Asp. 284/285 Pages: 607-612
• [Journal Article] Characterization and Catalytic Performances of Three Dimensional Mesoporous FeSBA-1 Catalysts (2006)
  • Author(s): Vinu, Ajayan, Krithiga, Thangavelu, Balasubramanian, Veerappan V., Asthana, Anjana, Srinivasu, Pavuluri, Mori, Toshiyuki, Ariga, Katsuhiko, Ramanath, Ganapathiraman, Ganesan, Pethuraia G.
  • Journal Title: J. Phys. Chem. B. 110(24) Pages: 11924-11931
• [Journal Article] Recent Progresses on Bio-Inorganic Nanohybrids (2006)
  • Author(s): Ariga, Katsuhiko, Vinu, Ajayan, Miyahara, Masahiko
  • Journal Title: Curr. Nanosci. 2(3) Pages: 197-210
• [Journal Article] Immobilization of Biomaterials to Nano-Assembled Films (Self-Assembled Monolayers, Langmuir-Blodgett Films, and Layer-by-Layer Assemblies) and Their Related Functions (2006)
  • Author(s): Ariga, Katsuhiko, Nakanishi, Takashi, Michinobu, Tsuyoshi
  • Journal Title: J. Nanosci. Nanotechnol. 6(8) Pages: 2278-2301
• [Journal Article] Chemically Non-equivalent Sites in Mesoporous BCN Revealed by Solid State NMR at21.8T (2006)
  • Author(s): Murakami, Miwa, Shimizu, Tadashi, Tansho, Masataka, Vinu, Ajayan, Ariga, Katsuhiko, Takegoshi, Kiyonori
  • Journal Title: Chem. Lett. 35(9) Pages: 986-987
• [Journal Article] Room Temperature Liquid Fullerenes : An Uncommon Morphology of C_<60> Derivatives (2006)
  • Author(s): Michinobu, Tsuyoshi, Nakanishi, Takashi, Hill, Jonathan P, Funabashi, Masahiro, Ariga, Katsuhiko
  • Journal Title: J. Am. Chem. Soc. 128(32) Pages: 10384-10385
• [Journal Article] A Chromogenic Indicator for Anion Reporting Based on an N-Substituted Oxoporphyrinogen (2006)
  • Author(s): Hill, Jonathan P., McCarty, Amy Lea, D'Souza, Francis, Labuta, Jan, Redshaw, Carl, Elsegood, Mark R.J., Aoyagi, Masaru, Nakanishi, Takashi, Ariga, Katsuhiko
  • Journal Title: Inorg. Chem. 45(20) Pages: 8288-8296
• [Journal Article] ナノテクに貢献する超分子の技 (2006)
  • Author(s): 有賀克彦
  • Journal Title: 化学と教育 54(9) Pages: 492-493
• [Journal Article] How Molecules Accommodate a 2D Crystal Lattice Mismatch : an Unusual 'Mixed' Conformation of Tetraphenylporphyrin (2006)
  • Author(s): Hill, Jonathan P., Wakayama, Yutaka, Ariga, Katsuhiko
  • Journal Title: Phys. Chem. Chem. Phys. 8(43) Pages: 5034-5037
• [Journal Article] Mechanical Control of Enantioselectivity of Amino Acid Recognition by Cholesterol-Armed Cyclen Monolayer at the Air-Water Interface (2006)
  • Author(s): Michinobu, Tsuyoshi, Shinoda, Satoshi, Nakanishi, Takashi, Hill, Jonathan P., Fujii, Kazuko, Player, Tomoko N., Tsukube, Hiroshi, Ariga, Katsuhiko
  • Journal Title: J. Am. Chem. Soc. 128(45) Pages: 14478-14479
• [Journal Article] 二次元分子パターニング (2006)
  • Author(s): 中西尚志, 有賀克彦
  • Journal Title: 表面 44(11) Pages: 415-432
• [Journal Article] New Families of Mesoporous Materials (2006)
  • Author(s): Vinu, Ajayan, Mori, Toshiyuki, Ariga, Katsuhiko
  • Journal Title: Sci. Technol. Adv. Mater. 7(8) Pages: 753-771
• [Book] Supramolecular Chemistry -Fundamentals and Applications- (2006)
  • Author(s): Ariga, Katsuhiko, Kunitake, Toyoki
  • Total Pages: 208
  • Publisher: Springer-Verlag