Multifunctional Nano-Scanning Electrochemical Microscopy

2008 Fiscal Year Self-evaluation Report

• Project/Area Number: 18101006
• Research Category: Grant-in-Aid for Scientific Research (S)
• Allocation Type: Single-year Grants
• Research Field: Microdevices/Nanodevices
• Research Institution: Tohoku University
• Principal Investigator: MATSUE Tomokazu Tohoku University, 大学院・環境科学研究科, 教授 (70173797)
• Project Period (FY): 2006 – 2009
• Keywords: マイクロ化学システム / 単一細胞計測

Research Abstract

マイクロ・ナノ電極をプローブとした電気化学顕微鏡システムに機能性分子修飾, 近接場光計測及びイオン電流計測を付加した多機能ナノ電気化学顕微鏡を開発すると共に単一細胞レベルでの多項目定量解析手法を確立し, 新規細胞診断システムへ展開させる.

Research Products

• [Journal Article] Construction of Time-Lapse Scanning Electrochemical Microscopy with Temperature Control and Its Application To Evaluate the Preservation Effects of Antifreeze Proteins on Living Cells (2008)
  • Author(s): Y. Hirano, Y. Nishimiya, K. Kowata, F. Mizutani, S. Tsuda, Y. Komatsu
  • Journal Title: Anal. Chem. 80 Pages: 9349-9354
  • Peer Reviewed
• [Journal Article] Fabrication of a shear force-based ion-selective capillary probe for scanning electrochemical microscopy (2008)
  • Author(s): H. Yamada, Y. Ikuta Y, T. Koike T, T. Matsue
  • Journal Title: Chem. Lett. 37 Pages: 392-393
  • Peer Reviewed
• [Journal Article] Microcontact printed diaphorase monolayer on glass characterized by atomic force microscopy and scanning electrochemical microscopy (2007)
  • Author(s): H. Q. Luo, H. Shiku, A. Kumagai, Y. Takahashi, T. Yasukawa, T. Matsue
  • Journal Title: Electrochem. Commun. 9 Pages: 2703-2708
  • Peer Reviewed
• [Journal Article] Electrochemical screening of recombinant protein solubility in Escherichia coli using scanning electrochemical microscopy (SECM) Biotech (2007)
  • Author(s): K. Nagamine, S. Onodera, A. Kurihara, T. Yasukawa, H. Shiku, R. Asano, I. Kumagai, T. Matsue
  • Journal Title: Bioeng 96 Pages: 1008-1013
  • Peer Reviewed
• [Journal Article] Topographic, Electrochemical, and Optical Images Captured Using Standing Approach Mode Scanning Electrochemical/Optical Microscopy (2006)
  • Author(s): Y. Takahashi, Y. Hirano, T. Yasukawa, H. Shiku, H. Yamada, T. Matsue
  • Journal Title: Langmuir 22 Pages: 10299-10306
  • Peer Reviewed
• [Journal Article] Electrochemical Detection of Epidermal Growth Factor Receptors on a Single Living Cell Surface by Scanning Electrochemical Microscopy
  • Author(s): Y. Takahashi, T. Miyamoto, H. Shiku, R. Asano, T. Yasukawa, I. Kumagai, T. Matsue
  • Journal Title: Anal. Chem. (in press)