2010 Fiscal Year Final Research Report
Modification of plant gene expression by viral gene silencing suppressors
| Project/Area Number |
18108001
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (S)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Plant pathology
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
UYEDA Ichiro Hokkaido University, 大学院・農学研究院, 教授 (10113523)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MASUTA Chikara 北海道大学, 大学院・農学研究院, 教授 (60281854)
NAKAHARA Kenji 北海道大学, 大学院・農学研究院, 助教 (90315606)
|
|---|
| Project Period (FY) |
2006 – 2010
|
| Keywords | 病原体相互作用 / 病原性因子 / サイレンシング / ウイルス |
|---|
| Research Abstract |
Plants defense against virus infection by Post Transcriptional Gene Silencing (PTGS). We analyzed how PTGS was involved in pathogenicity and obtained the following results. (1) Suppressor activity of viral HC-Pro gene is required for induction of necrotic symptoms. (2) rgs-CaM gene has affinity to many viral suppressor genes. Its interaction destabilizes bound proteins and consequently strengthen defense against virus infection by elevating PTGS activity. (3) Y satellite RNA of cucumber mosaic virus (Y-satRNA) induces bright yellow mosaic in tobacco instead of regular green mosaic. Molecular mechanism of how Y-satRNA induces yellow mosaic is elucidated.
|
-
-
-
-
-
-
-
-
[Journal Article] Silencing by small RNAs is linked to endosomal trafficking2009
Author(s)
Lee Y.S., Pressman S., Andress A.P., Kim K., White J.L., Cassidy J.J., Li1 X., Lubel1 K., Lim D.H., Cho I.S., Nakahara K., Preall1 J. B., Bellarel P., Sontheimer1 E.J., Carthew R.W.
-
Journal Title
Nature Cell Biology 11
Pages: 1150-1156
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
