2009 Fiscal Year Final Research Report
Application of nanoLC/MS/MS to legal medicine
| Project/Area Number |
18209025
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Nagoya University (2007-2009)
Fujita Health University (2006) |
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Principal Investigator |
ISHII Akira Nagoya University, 大学院・医学系研究科, 教授 (30252175)
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| Co-Investigator(Kenkyū-buntansha) |
KANEKO Rina 名古屋大学, 大学院・医学系研究科, 助教 (70367697)
HIRAOKA Kenzo 山梨大学, クリーンエネルギーセンター, 特任教授 (80107218)
HIRATA Yukari 藤田保健衛生大学, 医学部, 助教 (50156676)
HAMAJIMA Makoto 藤田保健衛生大学, 医学部, 助教 (20189608)
TAKAMIZAWA Jun 山梨大学, クリーンエネルギーセンター, 科学技術振興研究員 (80377605)
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| Project Period (FY) |
2006 – 2009
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| Keywords | 高速液体クロマトグラフィー / 質量分析 / エレクトロスプレー / 大気圧化学イオン化 / ナノスケールLC / プローブエレクトロスプレー / マッシブクラスターイオン衝撃 / SIMS / UPLC |
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| Research Abstract |
High performance-liquid chromatography/tandem mass spectrometers (LC/MS/MS) are widely used not only in biology, but also in forensic sciences. In this project, we have developed an ultrasensitive method for determining poisons and pharmaceuticals using a nanoscale LC (nanoLC)/MS/MS. Also, new ionization methods for LC/MS have been developed, and some methods were applied to legal medicine.
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