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2008 Fiscal Year Final Research Report

Clinical trials for the establishment of standard radiation therapy methods for early cancers

Research Project

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Project/Area Number 18209040
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionTohoku University

Principal Investigator

YAMADA Shogo  Tohoku University, 教授 (60158194)

Co-Investigator(Kenkyū-buntansha) HAREYAMA Masato  札幌医科大学, 医学部, 教授 (10173098)
NAKAMURA Kazumasa  九州大学, 病院, 准教授 (20284507)
SIRATO Hiroki  北海道大学, 医学系研究科, 教授 (20187537)
NEMOTO Kenji  山形大学, 医学部, 教授 (10208291)
NISHIMURA Yasumasa  近畿大学, 医学部, 教授 (00218207)
HAYABUCHI Naohumi  久留米大学, 医学部, 教授 (20108731)
ONISHI Hiroshi  山梨大学, 医学部, 准教授 (30213804)
TESHIMA Teruki  大阪大学, 医学系研究科, 教授 (40136049)
OGAWA Yoshihiro  東北大学, 大学院・医学系研究科, 准教授 (00169202)
OUCHI Noriaki  東北大学, 大学院・医学系研究科, 教授 (90203710)
MORIYA Takuya  川崎医科大学, 医学部, 教授 (00230160)
ARIGA Hisanori  東北大学, 病院, 講師 (30333818)
NAKATA Eiko  東北大学, 大学院・医学系研究科, 助教 (60375201)
HUKAO Akira  山形大学, 大学院・医学系研究科, 教授 (80156736)
ABE Yoshinao  弘前大学, 医学部, 教授 (10167950)
TOITA Takahumi  琉球大学, 医学部, 准教授 (30237036)
TSUJII Hirohiko  独立行政法人放射線医学総合研究所, 理事 (50088853)
SHIBAMOTO Yuta  名古屋市立大学, 医学系研究科, 教授 (20144719)
SASAKI Ryohei  神戸大学, 医学部附属病院, 准教授 (30346267)
HISHIKAWA YOSHIO  神戸大学, 医学系研究科, 教授 (20122335)
Project Period (FY) 2006 – 2008
Keywords放射線治療 / 早期の癌 / 標準的放射線治療 / 臨床試験 / 定位放射線治療 / 強度変調放射線治療(IMRT) / 粒子線治療 / 化学放射線療法
Research Abstract

画像診断の進歩により早期の癌が高率に発見されるようになり、またQOL重視の風潮の中で早期のがんに対する放射線治療の役割が急増している。しかし、治癒の可能性の高いこれらの癌に対する標準的放射線治療方法はいまだ確立していない。私どもは種々の早期のがんに対して全国集計を行い、結果を解析し、標準的と考えられる治療方法を提示してきた。さらに、標準的治療方法確立のために種々の臨床試験の提案を行い、実行してきた。

  • Research Products

    (33 results)

All 2008 2007 2006

All Journal Article (17 results) (of which Peer Reviewed: 14 results) Presentation (6 results) Book (10 results)

  • [Journal Article] Patterns of pretreatment diagnostic assessment and staging for patients with cervical cancer (1999-2001) : Patterns of Care Study in Japan2008

    • Author(s)
      Toita T, et al
    • Journal Title

      Jpn J Clin Oncol 38

      Pages: 26-30

    • Peer Reviewed
  • [Journal Article] Japanese structure survey of radiation oncology in 2005 based on institutional stratification of patterns of care study2008

    • Author(s)
      Teshima T, et al
    • Journal Title

      Int.J.radiation Oncology Biol.Phys 72

      Pages: 144-152

    • Peer Reviewed
  • [Journal Article] 特集・放射線治療 : 切らずに治す早期の癌 (1)2008

    • Author(s)
      山田章吾
    • Journal Title

      映像情報 Medical 40(11)

      Pages: 1001-1013

  • [Journal Article] 特集・放射線治療 : 切らずに治す早期の癌 (2)2008

    • Author(s)
      山田章吾
    • Journal Title

      映像情報 Medical 40(12)

      Pages: 1127-1144

  • [Journal Article] External-beam radiotherapy for localized or locally advancedprostate cancer in Japan : a multi-institutional outcome analysis2008

    • Author(s)
      Nakamura K, et al
    • Journal Title

      Jpn J Clin Oncol 38(3)

      Pages: 200-204

    • Peer Reviewed
  • [Journal Article] Current topics in breast cancer clinical research, 20072008

    • Author(s)
      Ohuchi N, et al
    • Journal Title

      Int J Clin Oncol 13(1)

      Pages: 1-2

    • Peer Reviewed
  • [Journal Article] Primary central nervous system lymphoma in Japan : changes in clinical features, treatment and prognosis during 1985-20042008

    • Author(s)
      Shibamoto Y, et al
    • Journal Title

      Neuro-Oncology 10

      Pages: 560-568

    • Peer Reviewed
  • [Journal Article] A phase II study on stereotactic body radiotherapy for stage I non-small cell lung cancer2007

    • Author(s)
      Koto M, Yamada S, et al
    • Journal Title

      85(3)

      Pages: 429-434

    • Peer Reviewed
  • [Journal Article] Dosimetric factors used for thoracic X-ray radiotherapy are not predictive of the occurrence of radiation pneumonitis after carbon-ion radiotherapy2007

    • Author(s)
      Koto M, Yamada S, et al
    • Journal Title

      213(2)

      Pages: 149-56

    • Peer Reviewed
  • [Journal Article] 国のがん対策における放射線治療の位置づけ2007

    • Author(s)
      山田章吾
    • Journal Title

      日放腫会誌 9(2)

      Pages: 92-92

  • [Journal Article] Significance of pathological evaluation for lymphatic vessel invasion in invasive breast cancer2007

    • Author(s)
      Ito M, Moriya T, et al
    • Journal Title

      Breast Cancer 14

      Pages: 381-387

    • Peer Reviewed
  • [Journal Article] Phase I/II trial of sequential chemoradiotherapy using a novel hypoxic cell radiosensitizer, Doranidazole (PR-350), in patients with locally advanced non-small cell lung cancer (WJTOG-0002)2007

    • Author(s)
      Nishimura Y, Nakagawa K, Takeda K, et al
    • Journal Title

      Int J Radiat Oncol Biol Phys 69

      Pages: 786-792

    • Peer Reviewed
  • [Journal Article] Low-dose radiation therapy for steroid resistant Kasabach-Meriritt Syndrome2007

    • Author(s)
      Nemoto K, Yamada S, et al
    • Journal Title

      Yamagata Med J 25

      Pages: 27-32

    • Peer Reviewed
  • [Journal Article] Development of an implantable real time micro dosimeter system. Future medical engineering based on bio-nanotechnology2006

    • Author(s)
      Yamada S, et al
    • Journal Title

      21st century COE program. Annual report 2004

      Pages: 53-54

    • Peer Reviewed
  • [Journal Article] S-1, an oral fluoropyrimidine, enhances rdiation response of DLD-1/FU human colon cancer xenografts resistant to 5-FU2006

    • Author(s)
      Nakata E, et al
    • Journal Title

      Oncology reports 16

      Pages: 465-471

    • Peer Reviewed
  • [Journal Article] Results of radiation therapy for superficial esophageal cancer using standard radiotherapy method recommended by Japanese Society of Therapeutic Radiology and Oncology (JASTRO) study group2006

    • Author(s)
      Nemoto K, et al
    • Journal Title

      Anti Cancer Res 26

      Pages: 1507-1512

    • Peer Reviewed
  • [Journal Article] New trends of immunohistochemistry for making differential diagnosis of breast lesions2006

    • Author(s)
      Moriya T, et al
    • Journal Title

      Med.Mol.Morphol 39(1)

      Pages: 8-13

    • Peer Reviewed
  • [Presentation] Stereotactic body radiotherapy with the use of patient voluntary breath-hold method and a CT-linac unit for 105 patients with stage I non-small cell lung cancer-Is four fractions of 12 Gy is adequate?2008

    • Author(s)
      H Onishi, Y Nagata, H Shirato, et al
    • Organizer
      American Society for Therapeutic Radiology and Oncology 50th annual meeting
    • Place of Presentation
      Boston, USA
    • Year and Date
      20080921-20080925
  • [Presentation] Prospective comparison of outcome in patients with resectable thoracic esophageal cancer receiving chemoradiotherapy and patients undergoing surgery2008

    • Author(s)
      Ariga H, Ogawa Y, Takeda K, et al
    • Organizer
      ANNUAL MEETING OF THE EUROPEAN SOCIETY FOR THERAPEUTIC RADIOLOGY AND ONCOLOGY
    • Place of Presentation
      Gothenburg, Sweden
    • Year and Date
      20080914-20080918
  • [Presentation] Chemo-radiotherapy for resectable esophageal cancer2008

    • Author(s)
      Yamada S
    • Organizer
      3^<rd> Tohoku Panama Seminar
    • Place of Presentation
      パナマ
    • Year and Date
      2008-07-29
  • [Presentation] Static and moving phantom studies for treatment planning in an integrated PET/CT system2007

    • Author(s)
      Nishimura Y, et al
    • Organizer
      the 49th Annual Meeting of the American Society for Therapeutic Radiology and Oncology
    • Place of Presentation
      Los Angels, CA, USA
    • Year and Date
      20071028-20071101
  • [Presentation] Pelvic node control in patients with locally advanced uterine cervical cancer treated with concurrent chemoradiotherapy2007

    • Author(s)
      Toita T, et al
    • Organizer
      ASCO Annual Meeting
    • Place of Presentation
      シカゴ
    • Year and Date
      20070601-20070605
  • [Presentation] 食道癌治療患者のQOL : 化学放射線療法と手術症例とを比較して2007

    • Author(s)
      有賀久哲
    • Organizer
      第66回日本医学放射線学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      20070413-20070415
  • [Book] 放射線治療ガイドライン20082008

    • Author(s)
      根本建二, 山田章吾
    • Total Pages
      292
    • Publisher
      メディカル教育研究社
  • [Book] 切らないがん治療~東海最先端ガイド~2008

    • Author(s)
      芝本雄太, 監修
    • Total Pages
      221
    • Publisher
      中日新聞社
  • [Book] 医療放射線2008

    • Author(s)
      淡河恵津世, 早渕尚文
    • Total Pages
      82-93
    • Publisher
      株式会社慧文社
  • [Book] 放射線治療を受けるがん患者の看護ケア2008

    • Author(s)
      菱川良夫, 佐々木良平
    • Total Pages
      190
    • Publisher
      日本看護協会出版社
  • [Book] Laser-Driven Relativistic Plasmas Applied for Science, Industry, and Medicine2008

    • Author(s)
      M. Murakami, Y. Hishikawa, et al
    • Total Pages
      275-300
    • Publisher
      AIP Conference Proceedings
  • [Book] 放射線治療の対象となる腫瘍とその病期(セカンドオピニオン実践ガイド)2007

    • Author(s)
      根本建二
    • Total Pages
      68-72
  • [Book] エビデンス放射線治療2007

    • Author(s)
      晴山雅人, 平岡真寛, 西村恭昌, 菱川良夫, 白土博樹, 芝本雄太, 大西洋, 戸板孝文, 他
    • Total Pages
      456
    • Publisher
      中外医学社
  • [Book] 早期のがん治療法の選択-放射線治療-2006

    • Author(s)
      山田章吾
    • Total Pages
      200
    • Publisher
      金原出版
  • [Book] 放射線治療マニュアル (改訂第2版) : 治療計画の手順2006

    • Author(s)
      晴山雅人
    • Total Pages
      7-23
    • Publisher
      中外医学社
  • [Book] 実践デジタルマンモグラフィ : 基礎から診断まで2006

    • Author(s)
      大内憲明, 編
    • Total Pages
      193
    • Publisher
      中山書店

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Published: 2011-06-18   Modified: 2016-04-21  

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