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2008 Fiscal Year Annual Research Report

精密血流画像解析法の新規開発による動・門脈血流の分離定量評価と肝発癌研究への応用

Research Project

Project/Area Number 18300176
Research InstitutionKinki University

Principal Investigator

工藤 正俊  Kinki University, 医学部, 教授 (10298953)

Co-Investigator(Kenkyū-buntansha) 宗像 浩  近畿大学, 医学部, 教授 (90111294)
村上 卓道  近畿大学, 医学部, 教授 (20252653)
Keywords肝細胞癌 / 前癌病変 / 肝腫瘍 / 純動脈相イメージング / Pure arterial phase imaging / 腺腫様過形成 / Levovist / Sonazoid
Research Abstract

造影ハーモニック法を用いることにより血管構築あるいは血流動態からみた肝腫瘍の鑑別診断が可能となってきた。すなわち肝細胞癌では周囲から蹴鞠状に流入する腫瘍血管および腫瘍濃染が明瞭に得られ、また転移性肝癌では腫瘍の辺縁のみに血流を認めること、ならびに肝血管腫では辺縁からpooling様に内部に染み込んでいく像により鑑別が可能である。ただし、前癌病変である腺腫様過形成は門脈血流が流入するが、この門脈血流をハーモニック法で検出することはこれまでは極めて困難であった。すなわち、肝動脈由来の血流と上腸間膜静脈から戻って門脈に入る一瞬の時間差を利用して血流が腫瘍に入るか否かを判定する必要があるため、視覚的な判定に頼らざるを得なかったため、診断が主観的になり客観的な評価は困難であった。今回われわれが開発した方法はraw data保存を利用して動脈血流と門脈血流を分離評価できる方法である。Sonazoidを用いることにより、そのraw data保存から検査後にpost processにて腫瘍ならびに腫瘍の外側の動脈や門脈に関心領域(ROI)をおき、その立ち上がりから純粋に動脈のみで栄養される数秒間を装置内でコンピューター解析で同定し、その時間だけのMIP画像を加算してaccumulation画像を作成すると動脈が栄養しているか否かを判定し得ることが明らかになった。また、その後の門脈と動脈の両方が入るmixed phaseにおいては両者の交じり合ったこのphaseで血流を認めれば、それは門脈血流が存在する結節であると評価できる。この点で純動脈相イメージ(pure arterial phase imaging)は結節内の動脈と門脈の分離評価を可能にする新しい手法と考えられる。

  • Research Products

    (105 results)

All 2009 2008 Other

All Journal Article (44 results) (of which Peer Reviewed: 44 results) Presentation (61 results)

  • [Journal Article] Multicentric occurrence of HCC detected 3-4 yerars after AFP-L3 positivity.2009

    • Author(s)
      Kim SR
    • Journal Title

      Internal Med (in press)

    • Peer Reviewed
  • [Journal Article] Value of liver parenchymal phase imaging of contrast-enhanced ultrasonography to diagnose the premalignant/borderline lesions and overt HCC.2009

    • Author(s)
      Inoue T
    • Journal Title

      AJR Am J Roentgenol (in press)

    • Peer Reviewed
  • [Journal Article] Multistep human hepatocarcinogenesis : correlation of imaging with pathology.2009

    • Author(s)
      Kudo M
    • Journal Title

      J Gastroenterol (in press)

    • Peer Reviewed
  • [Journal Article] International consensus on the pathologic diagnosis of early hepatocellular carcinoma : A report of the international consensus group for hepatocellular neoplasia.2009

    • Author(s)
      Wanless I
    • Journal Title

      Hepatology (in press)

    • Peer Reviewed
  • [Journal Article] Crohn's disease with gastroduodenal mucosa lesions that are similar to the lesions caused by ulcerative colitis.2009

    • Author(s)
      Umehara Y
    • Journal Title

      Inflamm Bowel Dis (in press)

    • Peer Reviewed
  • [Journal Article] Campylobacter fetus meningitis in a patient with Crohn's disease.2009

    • Author(s)
      Umehara Y
    • Journal Title

      Inflamm Bowel Dis (in press)

    • Peer Reviewed
  • [Journal Article] Two cases of non-alcoholic steato-hepatitis developing from simple fatty liver.2009

    • Author(s)
      Kim SR
    • Journal Title

      J Hepatol (in press)

    • Peer Reviewed
  • [Journal Article] Pegylated interferon plus ribavirin combination therapy for chronic hepatitis C with high viral load of serum HCV RNA, genotype 1b, discontinued on attaining sustained virological response in week 16 after onset of acute pancreatitis.2009

    • Author(s)
      Kim SR
    • Journal Title

      J Gastroint Liver Dis (in press)

    • Peer Reviewed
  • [Journal Article] Small cell carcinoma of the pancreas : Role of EUS-FNA in its confirmation and subsequent effective chemotherapy using carbop latin and etoposide.2009

    • Author(s)
      Sakamoto H
    • Journal Title

      J Gastroenterol (in press)

    • Peer Reviewed
  • [Journal Article] Prospective comparative study of the EUS guided 25-gauge FNA needle with the 19-gauge Trucut needle and 22-gauge FNA needle in patients with solid pancreatic masses.2009

    • Author(s)
      Sakamoto H
    • Journal Title

      J Gastroen Hepatol (in press)

    • Peer Reviewed
  • [Journal Article] Comparison of an ecabet sodium and proton pump inhibitor(PPI) combination therapy with PPI alone in the treatment of endoscopic submucosal dissection(ESD)-induced ulcers in early gastric cancer : prospective randomized study.2009

    • Author(s)
      Asakuma Y
    • Journal Title

      Hepatogastroenterol (in press)

    • Peer Reviewed
  • [Journal Article] Association of genetic polymorphism with interferon-induced he matologic adverse effects in chronic hepatitis C patients.2009

    • Author(s)
      Wada M
    • Journal Title

      J Viral Hepatitis (in press)

    • Peer Reviewed
  • [Journal Article] Pegylated interferon plus ribavirin combination therapy for chronic hepatitis C with high viral load of serum HCV RNA, genotype 1b, discontinued on attaining sustained virological response in week 16 after onset of acute pancreatitis.2009

    • Author(s)
      Kim SR
    • Journal Title

      Digestion (in press)

    • Peer Reviewed
  • [Journal Article] Endoscopic findings of intestinal Behcet's disease complicated with toxic megacolon.2009

    • Author(s)
      Umehara Y
    • Journal Title

      Endoscopy (in press)

    • Peer Reviewed
  • [Journal Article] Hepatectomy versus radiofrequency ablation for early hepatocelullar carcinoma : Reply.2009

    • Author(s)
      Hasegawa K
    • Journal Title

      J Hepatol (in press)

    • Peer Reviewed
  • [Journal Article] Comparison of endoscopic ultrasound guided directional e-FLOW using microbubble contrast gent with power Doppler and color Doppler in solid pancreatic lesions.2009

    • Author(s)
      Das K
    • Journal Title

      Ultrasound Med Biol (in press)

    • Peer Reviewed
  • [Journal Article] Transarterial infusion chemotherapy alone versus transarterial chemoembolization for the treatment of hepatocellular carcinoma : Results of a multicenter randomized phase III trial.2009

    • Author(s)
      Okusaka T
    • Journal Title

      Hepatology (in press)

    • Peer Reviewed
  • [Journal Article] Angiotensin-II type 1 receptor blocker and angiotensin-converting enzyme inhibitor suppress pancreatitis and fibrosis : in vitro study with rat pancreatic stellate cells and in vivo study with Wistar Bonn/Kobori Rats.2009

    • Author(s)
      Fukuta N
    • Journal Title

      Gastroenterology (in press)

    • Peer Reviewed
  • [Journal Article] Radiofrequency ablation guided by Sonazoid-enhanced harmonic US for occult hepatic malignancies resolved poorly on B-mode US2009

    • Author(s)
      Minami Y
    • Journal Title

      Radiology (in press)

    • Peer Reviewed
  • [Journal Article] Colic intussusception in a patient with Cronkhite-Canada syndrome is relieved by colonscopic redution.2009

    • Author(s)
      Minami Y
    • Journal Title

      Gastrointenst Endosc (in press)

    • Peer Reviewed
  • [Journal Article] A novel perfusion imaging technique of the pancreas : contrast-enhanced harmonic EUS (with video).2008

    • Author(s)
      Kitano M
    • Journal Title

      Gastrointest Endscopy 67

      Pages: 141-150

    • Peer Reviewed
  • [Journal Article] Mixed intestinal- and diffuse-type histology is a risk factor for lymph node metastasis of submucosal invasive gastric cancer.2008

    • Author(s)
      Tsuji N
    • Journal Title

      Digest Endosc 20

      Pages: 17-21

    • Peer Reviewed
  • [Journal Article] Usefulness of a new immunoradiometric assay of HCV core antigen to predict virological response during PEG-IFN/RBV combination therapy for chronic hepatitis with high viral load of serum HCV RNA genotye 1b.2008

    • Author(s)
      Sasase N
    • Journal Title

      Intervirology 51

      Pages: S70-S75

    • Peer Reviewed
  • [Journal Article] Elevated serum ALT levels during pegylated interferon monotherapy may be caused by hepatic iron overload.2008

    • Author(s)
      Nagashima M
    • Journal Title

      Intervirology 51

      Pages: S76-S85

    • Peer Reviewed
  • [Journal Article] Sonazoid-enhanced ultrasound in the diagnosis and treatment of hepatic tumors.2008

    • Author(s)
      Kudo M
    • Journal Title

      J Med Ultrasound 16

      Pages: 130-139

    • Peer Reviewed
  • [Journal Article] Prognostic value of pretreatment levels of tumor markers for hepatocellular carcinoma on survival after curative treatment of patients with HCC.2008

    • Author(s)
      Toyoda H
    • Journal Title

      J Hepatol 49

      Pages: 223-232

    • Peer Reviewed
  • [Journal Article] Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer : an open-label, randomised controlled trial.2008

    • Author(s)
      Fukase K
    • Journal Title

      Lancet 372

      Pages: 392-397

    • Peer Reviewed
  • [Journal Article] Endoscopic findings can predict the efficacy of leukocytapheresis for steroid-naive patients with moderately active ulcerative colitis.2008

    • Author(s)
      Umehara Y
    • Journal Title

      World J Gastroenterol 14

      Pages: 5316-5321

    • Peer Reviewed
  • [Journal Article] Defect reperfusion imaing, a newly developed novel technology using Sonazoid in the treatment of hepatocellular carcinoma.2008

    • Author(s)
      Kudo M
    • Journal Title

      J Med Ultrasound 16

      Pages: 169-176

    • Peer Reviewed
  • [Journal Article] Long-term follow-up of atypical progressive focal nodular hyperplasia increasing in size and number implicates its pathogenesis.2008

    • Author(s)
      Kudo M
    • Journal Title

      Am J Gastroenterol 103

      Pages: 2153-2155

    • Peer Reviewed
  • [Journal Article] Multistep progression from a hypovascular nodule to anodule-in-nodule type hepatocellular carcinoma in hepatitis C-related cirrhosis.2008

    • Author(s)
      Madan K
    • Journal Title

      Indian J Gastroenterol 27

      Pages: 176

    • Peer Reviewed
  • [Journal Article] Intracystic hemorrhage in a patient of polycystic kidney with renocolic fistula diagnosed by contrast-enhanced ultrasonography.2008

    • Author(s)
      Ishikawa E
    • Journal Title

      Internal Med 47

      Pages: 1977-1979

    • Peer Reviewed
  • [Journal Article] Hepatocellular ccarcinoma 2009 and beyond : from the surveillance to molecular targeted therapy.2008

    • Author(s)
      Kudo M
    • Journal Title

      Oncology 75

      Pages: S1-12

    • Peer Reviewed
  • [Journal Article] Epidemiology of hepatocellular carcinoma in Japan and Korea.2008

    • Author(s)
      Kim SR
    • Journal Title

      Oncology 75

      Pages: S13-16

    • Peer Reviewed
  • [Journal Article] Impact of interferon therapy after curative treatment of hepatocellular carcinoma.2008

    • Author(s)
      Kudo M
    • Journal Title

      Oncology 75

      Pages: S30-41

    • Peer Reviewed
  • [Journal Article] Sonazoid-enhanced ultrasonography for diagnosis of hepatic malignancies : comparison with contrast-enhanced CT.2008

    • Author(s)
      Hatanaka K
    • Journal Title

      Oncology 75

      Pages: S42-47

    • Peer Reviewed
  • [Journal Article] Imaging of hepatocellular carcinoma : qualitative and quantitative analysis of post-vascular phase contrast-enhanced US with Sonazoid ; comparison with superparamagnetic iron oxide magnetic resonance images.2008

    • Author(s)
      Inoue T
    • Journal Title

      Oncology 75

      Pages: S48-54

    • Peer Reviewed
  • [Journal Article] Intranodular blood supply correlates well with biological malignancy grade determined by tumor growth rate in pathologically proven hepatocellular carcinoma.2008

    • Author(s)
      Kudo M
    • Journal Title

      Oncology 75

      Pages: S55-64

    • Peer Reviewed
  • [Journal Article] Validation of a new prognostic staging system for heptaocellular carcinoma : a comparison of the biomarker combined Japan integrated staging (JIS) score, the conventional JIS score and the BALAD score.2008

    • Author(s)
      Kitai S
    • Journal Title

      Oncology 75

      Pages: S83-90

    • Peer Reviewed
  • [Journal Article] PIVKA-II is the best prognostic predictor in patients with hepatocellular carcinoma after radiofrequency ablation therapy.2008

    • Author(s)
      Takahashi S
    • Journal Title

      Oncology 75

      Pages: S91-98

    • Peer Reviewed
  • [Journal Article] Response evaluation of transcatheter arterial chemoembolizaion in hepatocellular carcinomas : the usefulness of Sonazoid-enhanced harmonic sonography.2008

    • Author(s)
      Xia Y
    • Journal Title

      Oncology 75

      Pages: S99-105

    • Peer Reviewed
  • [Journal Article] Combination therapy with S-1 and pegylated interferon alpha for advanced hepatocellular carcinoma.2008

    • Author(s)
      Ueshima K
    • Journal Title

      Oncology 75

      Pages: S106-113

    • Peer Reviewed
  • [Journal Article] Prognostic significance of intragastric pressure for the occurrence of aspiration pneumonia in the patients with percutaneous endoscopic gastrostomy(PEG).2008

    • Author(s)
      Kudo M
    • Journal Title

      Hepato-Gastroenterol 55

      Pages: 1935-1938

    • Peer Reviewed
  • [Journal Article] Focal nodular hyperplasia-like lesion with venous washout in a lcoholic liver cirrhosis.2008

    • Author(s)
      Kim SR
    • Journal Title

      Internal Med 47

      Pages: 1899-1903

    • Peer Reviewed
  • [Presentation] RFA-safety marginの必要性とそのevidence. シンポジウム「肝細胞癌治療における局所再発の抑制とSafety/Surgical marginの必要性-画像による判定」2009

    • Author(s)
      工藤正俊
    • Organizer
      第15回肝血流動態イメージ研究会
    • Place of Presentation
      パシフィコ横浜, 神奈川
    • Year and Date
      20090131-20090201
  • [Presentation] 自然退縮した肝細胞癌症例の画像所見と組織所見との比較.2009

    • Author(s)
      矢田典久
    • Organizer
      第15回肝血流動態イメージ研究会
    • Place of Presentation
      パシフィコ横浜, 神奈川
    • Year and Date
      20090131-20090201
  • [Presentation] 肝細胞癌外科治療におけるソナゾイドを用いた術中造影エコーの有用性2009

    • Author(s)
      土師誠二
    • Organizer
      第11回関西肝癌局所療法研究会
    • Place of Presentation
      阪急電鉄本社ビル, 大阪
    • Year and Date
      2009-03-07
  • [Presentation] Special Lecture "Sonazoid-enhanced US for liver tumors : Present status and future perspective.2008

    • Author(s)
      Kudo M
    • Organizer
      10^<th>International Symposium on Ultrasound Contrast Imaging, Tokyo Medical Hospital
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      20081212-20081214
  • [Presentation] Special Lecture "Treatment of single HCC in 2-5cm : Debate on gray zone. Non-surgical treatment : Eastern experience.2008

    • Author(s)
      Kudo M
    • Organizer
      6^<th> International Meeting Hepatocellular Carcinoma : Eastern and Western Experiences Current Issues of Hepatocellular Carcinoma
    • Place of Presentation
      Asian Medical Center, Seoul, Korea
    • Year and Date
      20081207-20081209
  • [Presentation] Special Lecture "U/s & EUS in diagnosis of pancreatic tumors2008

    • Author(s)
      Kudo M
    • Organizer
      6^<th> AFSUMB Workshop Delhi
    • Place of Presentation
      New Delhi, India
    • Year and Date
      20081122-20081123
  • [Presentation] Special Lecture "Is adjuvant therapy necessary after curative treatment of HCC? Low-dose, long-term maintenance interferon therapy after curative RFA increases survival in patients with hepatitis C-related HCC.2008

    • Author(s)
      Kudo M
    • Organizer
      6^<th> International Meeting Hepatocellular Carcinoma : Eastern and Western Experiences Current Issues of Hepatocellular Carcinoma
    • Place of Presentation
      Asian Medical Center, Seoul, Korea
    • Year and Date
      20081107-20081109
  • [Presentation] Qualitative and quantitative analysis of liver-parenchymal phase contrast-enhanced US with Sonazoid in detecting HCC ; Comparison with SPIO-MRI.2008

    • Author(s)
      Inoue T
    • Organizer
      16^<th> United Europian Gastroenterology Week (UEGW)
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      20081018-20081022
  • [Presentation] Value of liver parenchymal phase imaging of contrast-enhanced ultrasonography to diagnose the premalignant/borderline lesions and overt HCC.2008

    • Author(s)
      Inoue T
    • Organizer
      16^<th> United Europian Gastroenterology Week (UEGW)
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      20081018-20081022
  • [Presentation] Evaluation of the effectiveness of radiofrequency ablation for hepatic malignancies : Usefulness of virtual CT Sonography using magnetic navigation.2008

    • Author(s)
      Kitai S
    • Organizer
      16^<th> United Europian Gastroenterology Week (UEGW)
    • Place of Presentation
      Vienna Asutria
    • Year and Date
      20081018-20081022
  • [Presentation] Special Lecture "Impact of primovist on current diagnostic and therapeutic algorithm in HCC2008

    • Author(s)
      Kudo M
    • Organizer
      The 2^<nd> International Forum for Liver MRI 2008
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      20081017-20081018
  • [Presentation] 肝予備能良好かつ単発の肝細胞癌患者に対するラジオ波焼灼療法治療成績. パネルディスカッション「肝癌の病態別推奨治療 : コンセンサス形成を目指す異分野間衆議」2008

    • Author(s)
      鄭浩柄
    • Organizer
      第50回日本消化器病学会大会
    • Place of Presentation
      グランドプリンスホテル新高輪, 東京
    • Year and Date
      20081001-20081004
  • [Presentation] 難治性C型慢性肝炎に対する治療戦略-後期陰性化症例における検討-. シンポジウム「C型肝炎 ; PEG-Riba治療のコンセンサス」2008

    • Author(s)
      上田泰輔
    • Organizer
      第50回日本消化器病学会大会
    • Place of Presentation
      グランドプリンスホテル新高輪, 東京
    • Year and Date
      20081001-20081004
  • [Presentation] 進行肝細胞癌に対するソラフェニブの使用経験. シンポジウム「肝癌の分子標的治療」2008

    • Author(s)
      上嶋一臣
    • Organizer
      第12回日本肝臓学会大会
    • Place of Presentation
      グランドプリンスホテル新高輪, 東京
    • Year and Date
      20081001-20081003
  • [Presentation] 肝細胞癌根治後C型肝癌に対するIFN少量長期維持療法の生命予後改善効果に関する検討. シンポジウム「肝細胞癌治療後の抗ウイルス療法は予後を改善するか」2008

    • Author(s)
      上田泰輔
    • Organizer
      第12回日本肝臓学会大会
    • Place of Presentation
      グランドプリンスホテル新高輪, 東京
    • Year and Date
      20081001-20081003
  • [Presentation] Sonazoidを用いた造影超音波ガイド下ラジオ波焼灼術の有用性2008

    • Author(s)
      南康範
    • Organizer
      第12回日本肝臓学会大会
    • Place of Presentation
      グランドプリンスホテル新高輪, 東京
    • Year and Date
      20081001-20081003
  • [Presentation] 肝腫瘍の診断におけるDefect Re-perfusion Imagingの有用性について. ワークショップ「新生代超音波造影剤導入による肝癌診断・治療の変革」2008

    • Author(s)
      畑中絹世
    • Organizer
      第12回日本肝臓学会大会
    • Place of Presentation
      グランドプリンスホテル新高輪, 東京
    • Year and Date
      20081001-20081003
  • [Presentation] ソナゾイド造影超音波検査におけるpost vascular phase imagingとSPIO-MRIとの比較2008

    • Author(s)
      井上達夫
    • Organizer
      第12回日本肝臓学会大会
    • Place of Presentation
      グランドプリンスホテル新高輪, 東京
    • Year and Date
      20081001-20081003
  • [Presentation] Child-Pugh C型肝硬変に合併した肝癌は治療すべきか? その是非と治療法選択に関するRetrospectivee多施設共同研究. パネルディスカッション「肝癌の病態別推奨治療 : コンセンサス形成を目指す異分野間衆議」2008

    • Author(s)
      大崎往夫
    • Organizer
      第12回日本肝臓学会大会
    • Place of Presentation
      グランドプリンスホテル新高輪, 東京
    • Year and Date
      20081001-20081003
  • [Presentation] Invited Lecture "Contrast-enhanced US with new contrast agent, Sonazoid for liver tumors" Australasian Society for Ultrasound in Medicine2008

    • Author(s)
      Kudo M
    • Organizer
      38^<th> Annual Scientific Meeting
    • Place of Presentation
      New Zealand
    • Year and Date
      20080918-20080921
  • [Presentation] Separate analysis of intranodular blood supply in nodular lesions associated with liver cirrhosis : a novel ultrasound technique "pure arterial phase imaging2008

    • Author(s)
      Kudo M
    • Organizer
      2^<nd> International Liver Cancer Association (ILCA) 2008 Annual Conference
    • Place of Presentation
      Chicago, USA
    • Year and Date
      20080905-20080907
  • [Presentation] A proposal of novel treatment-assist technique in the Sonazoid-en hanced ultrasonography : value of defect re-perfusion imaging.2008

    • Author(s)
      Kudo M
    • Organizer
      2^<nd> International Liver Cancer Association (ILCA) 2008 Annual Conference
    • Place of Presentation
      Chicago, USA
    • Year and Date
      20080905-20080907
  • [Presentation] Phase I/II study of the efficacy and safety of S-1 in patients (PTS) with advanced hepatocellular carcinoma(HCC).2008

    • Author(s)
      Kudo M
    • Organizer
      2^<nd> International Liver Cancer Association (LCA)2008 Annual Conference
    • Place of Presentation
      Chicago, USA
    • Year and Date
      20080905-20080907
  • [Presentation] 日本肝癌研究会全国原発追跡調査の現状と課題2008

    • Author(s)
      猪飼伊知夫
    • Organizer
      第63回消化器外科学会定期学術総会 シンポジウム
    • Place of Presentation
      ロイトン札幌, 北海道
    • Year and Date
      20080716-20080718
  • [Presentation] Invited Lecture "Hepatocellular carcinoma : current topics in the diagnosis and treatment2008

    • Author(s)
      Kudo M
    • Organizer
      LAENNEC SOCIETY : SUMMER MEETING
    • Place of Presentation
      Padova, Italy.
    • Year and Date
      20080709-20080711
  • [Presentation] Phase I/II study of S-1 in patients (pts) with advanced hepatocellular carcinoma (HCC) : Results of the pgase II part.2008

    • Author(s)
      Okusaka T
    • Organizer
      2008 Annual Meeting, AMERICAN SOCIETY OF CLINICAL ONCOLOGY
    • Place of Presentation
      Chicago, USA
    • Year and Date
      20080530-20080603
  • [Presentation] Contrast enhanced sonography for hepatic malignancies : value of Defect Re-injection Test.2008

    • Author(s)
      Hatanaka K
    • Organizer
      DDW (Digestive Disease Week) 2008
    • Place of Presentation
      San Diego, USA
    • Year and Date
      20080517-20080522
  • [Presentation] Usefulness of virtual CT Sonography using magnetic navigation.2008

    • Author(s)
      Kitai S
    • Organizer
      DDW (Digestive Disease Week) 2008
    • Place of Presentation
      San Diego, USA
    • Year and Date
      20080517-20080522
  • [Presentation] 難治性C型慢性肝炎(I型高ウイルス量)に対するPEG-IFN α2b/Ribavirin併用療法の長期投与成績と安全性について2008

    • Author(s)
      石川恵美
    • Organizer
      第49回日本消化器病学会総会
    • Place of Presentation
      マリンメッセ福岡, 福岡
    • Year and Date
      20080508-20080510
  • [Presentation] Superiority of atrerioportal angiography to contrast-enhanced CT and MRI in the diagnosis of hepatocellular carcinoma in nodules smaller than 2cm.2008

    • Author(s)
      Kim SR
    • Organizer
      The 43^<rd> Annual Meeting of the Europian Association for the Study of the Liver
    • Place of Presentation
      Milan, Italy
    • Year and Date
      20080423-20080427
  • [Presentation] Surgical resection vs. percutaneous ablation for hepatocellular carcinoma : a preliminary report of the Japanese nationwide survey. Copenhagen2008

    • Author(s)
      Hasegawa K
    • Organizer
      The 44^<th> Annual Meeting of the European Association for the Study of the liver
    • Place of Presentation
      Denmark
    • Year and Date
      20080422-20080426
  • [Presentation] 各種肝腫瘤のソナゾイド造影超音波による質的診断評価. パネルディスカッション「造影エコーの現状と未来-造影イメージから病態解明ヘ-」2008

    • Author(s)
      前川清
    • Organizer
      日本超音波医学会第35回関西地方会学術集会
    • Place of Presentation
      神戸国際会議場, 兵庫
    • Year and Date
      2008-12-06
  • [Presentation] 振幅変調法によるソナゾイド造影超音波撮像法の使用経験.2008

    • Author(s)
      前川清
    • Organizer
      日本超音波医学会第35回関西地方会学術集会
    • Place of Presentation
      神戸国際会議場, 兵庫
    • Year and Date
      2008-12-06
  • [Presentation] 肝腫瘤におけるDefect Re-perfusion Imagingの有用性について.2008

    • Author(s)
      畑中絹世
    • Organizer
      日本超音波医学会第35回関西地方会学術集会
    • Place of Presentation
      神戸国際会議場, 兵庫
    • Year and Date
      2008-12-06
  • [Presentation] 肝血管筋脂肪腫の一例.2008

    • Author(s)
      前野知子
    • Organizer
      日本超音波医学会第35回関西地方会学術集会
    • Place of Presentation
      神戸国際会議場, 兵庫
    • Year and Date
      2008-12-06
  • [Presentation] Special Lecture "How to screen2008

    • Author(s)
      Kudo M
    • Organizer
      APASL Consensus Development Meeting on Management of Hepatocellular Carcinooma
    • Place of Presentation
      Grand Hyatt Hotel, Nusa Dua, Bali
    • Year and Date
      2008-11-04
  • [Presentation] Special Lecture "Ultrasound2008

    • Author(s)
      Kudo M
    • Organizer
      APASL Consensus Development Meeting on Management of Hepatocellular Carcinooma
    • Place of Presentation
      Grand Hyatt Hotel, Nusa Dua, Bali
    • Year and Date
      2008-11-04
  • [Presentation] Special Lecture "Diagnostic algorithm2008

    • Author(s)
      Kudo M
    • Organizer
      APASL Consensus Development Meeting on Management of Hepatocellular Carcinooma
    • Place of Presentation
      Grand Hyatt Hotel, Nusa Dua, Bali
    • Year and Date
      2008-11-04
  • [Presentation] C型慢性肝炎に対するインターフェロン療法著効後に発症した肝細胞癌破裂の1例2008

    • Author(s)
      峯宏昌
    • Organizer
      日本消化器病学会近畿支部第89回例会
    • Place of Presentation
      大阪国際交流センター, 大阪
    • Year and Date
      2008-09-27
  • [Presentation] 肝内胆管癌にTS-1を投与し著効した1例2008

    • Author(s)
      西尾健
    • Organizer
      日本消化器病学会近畿支部第89回例会
    • Place of Presentation
      大阪国際交流センター, 大阪
    • Year and Date
      2008-09-27
  • [Presentation] 肝細胞癌におけるBiomarker Combined Japan Integrated Staging (bm-JIS) Scoreの有用性2008

    • Author(s)
      北井聡
    • Organizer
      日本消化器病学会近畿支部第89回例会
    • Place of Presentation
      大阪国際交流センター, 大阪
    • Year and Date
      2008-09-27
  • [Presentation] 肝細胞癌非合併の硬変変症例におけるBCAA製剤投与による生存率への寄与2008

    • Author(s)
      早石宗右
    • Organizer
      日本消化器病学会近畿支部第89回例会
    • Place of Presentation
      大阪国際交流センター, 大阪
    • Year and Date
      2008-09-27
  • [Presentation] Invited Lecture "Diffuse liver disease2008

    • Author(s)
      Kudo M
    • Organizer
      WFUMB 2008 WORKSHOP
    • Place of Presentation
      Ulaanbaatar, Mongolian
    • Year and Date
      2008-07-26
  • [Presentation] Invited Lecture "Contrast-enhanced us of hepatic tumors with Sonazoid2008

    • Author(s)
      Kudo M
    • Organizer
      WFUMB 2008 WORKSHOP
    • Place of Presentation
      Ulaanbaatar, Mongolian
    • Year and Date
      2008-07-26
  • [Presentation] Invited Lecture "Direct Re-perfusion Imaging with Sonazoid in the diagnosis and treatment of hepatic malignancies2008

    • Author(s)
      Kudo M
    • Organizer
      WFUMB 2008 WORKSHOP
    • Place of Presentation
      Ulaanbaatar, Mongolian
    • Year and Date
      2008-07-26
  • [Presentation] ソナゾイド造影超音波による肝腫瘤の質的診断評価2008

    • Author(s)
      前川清
    • Organizer
      第8回関西肝血流動態イメージ研究会
    • Place of Presentation
      オーバルホール, 兵庫
    • Year and Date
      2008-06-14
  • [Presentation] ソナゾイド造影超音波による肝癌局所療法の効果判定『特にDefect-reinjection-testと支援画像表示』2008

    • Author(s)
      前川清
    • Organizer
      日本超音波医学会第81回学術集会
    • Place of Presentation
      神戸国際会議場, 兵庫
    • Year and Date
      2008-05-25
  • [Presentation] Defect Re-inection imagingの有用性について2008

    • Author(s)
      畑中絹世
    • Organizer
      日本超音波医学会第81回学術集会
    • Place of Presentation
      神戸国際会議場, 兵庫
    • Year and Date
      2008-05-25
  • [Presentation] 肝臓エラストグラフィの定量化の試みと深部領域の感度の改善. パネルディスカッション「弾性の考え方と診断法 : 各領域における見方」2008

    • Author(s)
      藤本研治
    • Organizer
      日本超音波医学会第81回学術集会
    • Place of Presentation
      神戸国際会議場, 兵庫
    • Year and Date
      2008-05-23
  • [Presentation] Defect Re-injection Testの有用性とRFA治療支援. シンポジウム「RFA-STATE of ARTS」2008

    • Author(s)
      畑中絹世
    • Organizer
      第44回日本肝癌研究会
    • Place of Presentation
      大阪国際会議場, 大阪
    • Year and Date
      2008-05-22
  • [Presentation] 非B非C肝癌の臨床的特徴 : B型関連肝癌・C型関連肝癌との比較2008

    • Author(s)
      畑中絹世
    • Organizer
      第44回日本肝癌研究会
    • Place of Presentation
      大阪国際会議場, 大阪
    • Year and Date
      2008-05-22
  • [Presentation] MDCT、MRI画像診断によるHCCのRFA治療効果判定2008

    • Author(s)
      岡田真広
    • Organizer
      第44回日本肝癌研究会
    • Place of Presentation
      大阪国際会議場, 大阪
    • Year and Date
      2008-05-22
  • [Presentation] 進行肝細胞癌に対するS-1、ペグインターフェロン併用療法2008

    • Author(s)
      上嶋一臣
    • Organizer
      第49回日本消化器病学会総会
    • Place of Presentation
      福岡国際会議場, 福岡
    • Year and Date
      2008-05-09
  • [Presentation] Defect Re-injection Testの有用性について2008

    • Author(s)
      畑中絹世
    • Organizer
      第49回日本消化器病学会総会
    • Place of Presentation
      福岡国際会議場, 福岡
    • Year and Date
      2008-05-09
  • [Presentation] Multistep hepatocecarcinogenesis : Correlation of imaging with pathology. Session : Basic Aspects2008

    • Author(s)
      Kudo M
    • Organizer
      The 94^<th> Annual Meeting of the Japanese Society of Gastroenterology 1^<st> International Forum
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2008-05-09
  • [Presentation] HCV Core抗原、NS3蛋白によるTLR2を介するCross Torelanceの誘導シンポジウム「ウイルス肝炎・肝癌に対する生体防御」2008

    • Author(s)
      鄭浩柄
    • Organizer
      第49回日本消化器病学会総会
    • Place of Presentation
      福岡サンパレスホテル&ルーム, 福岡
    • Year and Date
      2008-05-08
  • [Presentation] Sonazoid^r造影超音波によるRFA治療の効果判定 : 特にDefect-reinjection-test (D-RIT)と支援画像表示2008

    • Author(s)
      前川清
    • Organizer
      第21回日本腹部造影エコー・ドプラ診断研究会
    • Place of Presentation
      秋葉原コンベンションホール, 東京
    • Year and Date
      2008-04-12
  • [Presentation] Sonazoid^rを用いた造影超音波ガイド下ラジオ波焼灼術の有用性2008

    • Author(s)
      南康範
    • Organizer
      第21回日本腹部造影エコー・ドプラ診断研究会
    • Place of Presentation
      秋葉原コンベンションホール, 東京
    • Year and Date
      2008-04-12
  • [Presentation] Patterns of local recurrence of hepatocellular carcinoma and liver metastasisafter radiofrequency.

    • Author(s)
      Okada M
    • Organizer
      2008 Annual Meeting, Radiological Society of North America (RSNA)
    • Place of Presentation
      Chicago, USA
    • Year and Date
      00001130-00001205
  • [Presentation] How to use liver-specific contrast agents on MRI and sonography : Enhancement patterns of Kupffer, Sinusoid and Hepatocyte using superparamagnetic iron oxide, Gd-EOB-DTPA, galactosepalmitic acid and NC100100.

    • Author(s)
      Okada M
    • Organizer
      2008 Annual Meeting, Radiological Society of North America (RSNA)
    • Place of Presentation
      Chicago, USA
    • Year and Date
      00001130-00001205
  • [Presentation] Experimental and early clinical studies of S-1, a novel oral DPD inhibitor, chemotherapy for advanced hepatocellular carcinoma.

    • Author(s)
      Yamashita T
    • Organizer
      The 59^<th> Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      00001030-00001104

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Published: 2010-06-11   Modified: 2016-04-21  

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