2009 Fiscal Year Final Research Report
Reductive Construction of Carbon Skeleton with Newly Designed Asymmetric Catalysts
| Project/Area Number |
18350049
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Nagoya University |
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Principal Investigator |
NISHIYAMA Hisao Nagoya University, 工学研究科, 教授 (40135421)
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| Project Period (FY) |
2006 – 2009
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| Keywords | 不斉合成 / 反応 |
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| Research Abstract |
New synthetic method of carbon skeletons and functional transformation has been examined with designed transition metal species, which has chiral oxazoline ligands. Via intermediates activated by silane or hydrogen, coupling reaction of esters or enones with aldehydes was promoted to form optically active compounds with diastereo- and enantio-selectivities.
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