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2008 Fiscal Year Self-evaluation Report

Study on production domestic animals biosynthesized conjugated fatty acids that carries anti-obesity effects

Research Project

  • PDF
Project/Area Number 18380169
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied animal science
Research InstitutionKinki University

Principal Investigator

SAEKI Kazuhiro  Kinki University, 生物理工学部, 教授 (10298937)

Project Period (FY) 2006 – 2009
Keywordsクローン家畜 / トランスジェニック家畜
Research Abstract

共役リノール酸は発ガン抑制や抗肥満などの効果が報告されている。本研究では共役リノール酸の生成に関わる遺伝子を家畜に導入してやれば、畜肉や乳汁中に共役リノール酸が蓄積し、それを摂取することで人の健康によい家畜を作出できるのではないかと考えた。

  • Research Products

    (13 results)

All 2009 2008 2007 2006 Other

All Journal Article (7 results) Presentation (5 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Functional expression of a humanized gene for an ・-3 fatty acid desaturase from scarlet flax intransfected bovine adipocytes and bovineembryos cloned from the cells2009

    • Author(s)
      Indo Y, Tatemizo A, Abe Y, Suzuki I, Matsumoto K, Hosoi Y, Kinoshita M, Mikami K, Murata N, Iritani A, Saeki K.
    • Journal Title

      Biochim Biophys Acta 1791

      Pages: 183-190

  • [Journal Article] Enhancement of histone acetylation by trichostatin A during in vitro fertilization of bovineoocytes affects cell number of the inner cell mass of the resulting blastocysts2009

    • Author(s)
      Ikeda S, Tatemizo A, Iwamoto D, Taniguchi S, Hoshino Y, Amano T, Matsumoto K, HosoiY, Iritani A, Saeki K
    • Journal Title

      Zygote (in press)

  • [Journal Article] Interaction between embryos and culture conditions during in vitro development2008

    • Author(s)
      Y Nagao, R Iijima, K Saeki
    • Journal Title

      Zygote 16

      Pages: 127-133

  • [Journal Article] 植物由来脂肪酸不飽和化酵素遺伝子を哺乳動物細胞において高発現させるためのコドン使用頻度の最適化2008

    • Author(s)
      印藤頼子, 松本和也, 細井美彦, 鈴木石根, 村田紀夫,入谷明, 佐伯和弘
    • Journal Title

      近畿大学生物理工学部紀要 22

      Pages: 33-41

  • [Journal Article] 初期G1期細胞によるウシ核移植胚におけるDNAのメチル化レベルの検討2007

    • Author(s)
      岩本太作, 笠松礼, 立溝篤宏, 谷口俊仁, 中本善之, 谷口俊仁, 出田篤司, 浦川真実, 青柳敬人, 細井美彦, 松本和也, 入谷明, 佐伯和弘
    • Journal Title

      近畿大学先端技術総合研究所紀要 12

      Pages: 25-31

  • [Journal Article] Early development in utero of bovine nuclear transfer embryos using early G1 and G0 phase cells2007

    • Author(s)
      Ideta A, Urakawa M, Aoyagi Y, Saeki K.
    • Journal Title

      Cloning Stem Cells 9

      Pages: 571-580

  • [Journal Article] 最近の遺伝子改変家畜の現況,とくに植物遺伝子を利用した家畜の脂質の改変2006

    • Author(s)
      佐伯和弘
    • Journal Title

      麻布大学雑誌 Vol.11-12

      Pages: 91-96

  • [Presentation] Successful Culture of Single Bovine Embryos Using Polydimethylsiloxane (PDMS) Micro-Well Plates Cured under LowPressure.2008

    • Author(s)
      K. Saeki, N. Kato, D. Iwamoto, S. Taniguchi.
    • Organizer
      10th World Conference on Animal Production
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      20081123-28
  • [Presentation] ポリジメチルシロキサン製マイクロウェルを用いたウシ胚の体外培養の検討2008

    • Author(s)
      岩本太作, 松井 孝徳, 中野 達也, 高橋 千明, 谷口 俊仁, 加藤 暢宏, 佐伯 和弘.
    • Organizer
      第15回日本胚移植研究会
    • Place of Presentation
      仙台市
    • Year and Date
      20080904-05
  • [Presentation] Production ofcloned bovine embryos derived fromamniotic cells of pregnant cows2008

    • Author(s)
      Taniguchi, S. Hayashi, N., Abe, Y., Iwamoto, D., Kishigami, S., Kishi, M., Kato, H., Mitani, T., Matsumoto, K., Hosoi, Y., Iritani, A., Nagao, Y., Saeki, K.
    • Organizer
      Annual Conference of the International Embryo Transfer Society
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      20080202-09
  • [Presentation] Effects of trichostatin A on DNA methylation in cloned bovine embryos2008

    • Author(s)
      Iwamoto, D., Kishigami, S., Taniguchi, S., Abe, Y., Matsui, T., Kasamatsu, A., TatemizoA. Mitani, T., Kato, H., Matsumoto, K., Hosoi, Y., Wakayama, T., Iritani, A. Saeki, K.
    • Organizer
      Annual Conference of the International Embryo Transfer Society
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      20080202-09
  • [Presentation] Effects of trichostatin A on gene expression and in-vitro development of bovine embryos cloned from transfected fibroblasts carrying a luciferase gene2007

    • Author(s)
      Iwamoto, D, Kishigami, S, Taniguchi, S, Matsumoto, K, Hosoi, Y, Iritani, A, Wakayama, T, Saeki, K.
    • Organizer
      6th Int'l Congress on Animal Reproduction
    • Place of Presentation
      Budapest, Hungary
    • Year and Date
      20070713-15
  • [Patent(Industrial Property Rights)] 脂肪酸不飽和化酵素遺伝子, 組換え発現ベクター, 脂肪酸不飽和化酵素遺伝子が導入された, 非ヒト動物細胞および非ヒト動物

    • Inventor(s)
      佐伯 和弘・印藤頼子・松本 和也・細井 美 彦・入谷 明
    • Industrial Property Number
      特願2007-227818

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Published: 2010-06-11   Modified: 2016-04-21  

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