2009 Fiscal Year Final Research Report
Development of petide array for diagnosis fo important protozoan diseases using one drop of blood sample.
| Project/Area Number |
18380181
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied veterinary science
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| Research Institution | Obihiro University of Agriculture and Veterinary Medicine |
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Principal Investigator |
IGARASHI Ikuo Obihiro University of Agriculture and Veterinary Medicine, 原虫病研究センター, 教授 (80159582)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Kazuya 国立感染症研究所, ウイルス研究室, 研究員 (00400078)
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| Co-Investigator(Renkei-kenkyūsha) |
XUAN Xuenan 帯広畜産大学, 原虫病研究センター, 教授 (10292096)
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| Research Collaborator |
ISEKI Hirohi 動物衛生研究所, ウイルス病研究チーム, 研究員
TAMAKI Shiho 帯広畜産大学, 畜産学科4年
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| Project Period (FY) |
2006 – 2009
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| Keywords | 重要原虫病 / 網羅的 / 診断 / ペプチド(プロテイン)アレイ / 血清 / 少量試料 |
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| Research Abstract |
Protozoan diseases such as babesiosis cause great economical losses to animal industry world-wide. Many amimals are imported from foreign countries to Japan every year, and it is important to prevent invasion of infected these animals to Japan at the edge of the water. Objective of the present study was to develop the serodiagnostic test that was able to diagnose protozoan diseases with one drop of the blood sample. The protein array using recombinant antigens were successfully established to detect two bovine Babesia species at the same time. By adding other protozoan antigens, novel serological diagnostics will be established for diagnosis of many protozoan diseases at a time in the future.
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Research Products
(45 results)
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[Journal Article] Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria2010
Author(s)
Hikosaka K, Watanabe YI, Tsuji N, Kita K, Kishine H, Arisue N, Palacpac NM, Kawazu SI, Sawai H, Horii T, Igarashi I, Tanabe K.
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Journal Title
Mol Biol Evol. 27(5)
Pages: 1107-1116
Peer Reviewed
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[Journal Article] Epidemiological survey of Theileria orientalis infection in grazing cattle in the eastern part of Hokkaido, Japan2009
Author(s)
Ota N, Mizuno D, Kuboki N, Igarashi I, Nakamura Y, Yamashina H, Hanzaike T, Fujii K, Onoe S, Hata H, Kondo S, Matsui S, Koga M, Matsumoto K, Inokuma H, Yokoyama N.
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Journal Title
J Vet Med Sci. 71(7)
Pages: 937-944
Peer Reviewed
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[Journal Article] Development of loop-mediated isothermal amplification (LAMP) method for diagnosis of equine piroplasmosis2007
Author(s)
Alhassan A, Thekisoe OM, Yokoyama N, Inoue N, Motloang MY, Mbati PA, Yin H, Katayama Y, Anzai T, Sugimoto C, Igarashi I.
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Journal Title
Vet Parasitol. 143
Pages: 155-160
Peer Reviewed
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[Journal Article] Glycophorin A-knockout mice, which lost sialoglycoproteins from the red blood cell membrane, are resistant to lethal infection of Babesia rodhaini2007
Author(s)
Takabatake N, Okamura M, Yokoyama N, Ikehara Y, Akimitsu N, Arimitsu N, Hamamoto H, Sekimizu K, Suzuki H, Igarashi I.
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Journal Title
Vet Parasitol. 148
Pages: 93-101
Peer Reviewed
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[Presentation] タイにおけるウシバベシア症の疫学調査2008
Author(s)
周麗佳, 井関博, Tawin Inpankaew, 横山直明, 玄学南, Sathaporn Jittapalapong, 五十嵐郁男
Organizer
第146回日本獣医学会学術集会
Place of Presentation
シーガイア(宮崎県)
Year and Date
20080924-20080926
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[Book] 犬・猫の感染症と寄生虫病2007
Author(s)
長谷川篤彦, 監訳
Total Pages
293-297, 303-309, 310-312, 313-314, 315-318, 328-332, 333-337
Publisher
インターズー
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