Analysis of endosome/post-endosome system with special reference to water channel aquaporin 2

2008 Fiscal Year Self-evaluation Report

• Project/Area Number: 18390057
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: General anatomy (including Histology/Embryology)
• Research Institution: Gunma University
• Principal Investigator: TAKATA Kuniaki Gunma University, 大学院・医学系研究科, 教授 (20129290)
• Project Period (FY): 2006 – 2009
• Keywords: アクアポリン2 / エンドソーム / 小胞 / トラッフィッキング / 水輸送

Research Abstract

細胞表面機能分子の数が細胞内小胞からの移行や回収によって調節されている系の中で、水チャネル・アクアポリン2(AQP2)は、エンドソーム系により調節がおこなわれている。本研究では、AQP2をモデルとしてエンドソーム・ポストエンドソーム系の新たな機能に光を当てる。

Research Products

• [Journal Article] Localization and trafficking of aquaporin 2 in the kidney (2008)
  • Author(s): Takata K, Matsuzaki T, Tajika Y, Ablimit A, & Hasegawa H
  • Journal Title: Hisochem Cell Biol 130 Pages: 187-209
  • Peer Reviewed
• [Journal Article] Internalization of caveolae and their relationship with endosomes in cultured human and mouse endothelial cells (2007)
  • Author(s): Aoki T, Hagiwara H, Matsuzaki T, Suzuki T & Takata K
  • Journal Title: Anat Sci Int 82 Pages: 82-97
  • Peer Reviewed
• [Journal Article] Differential localization of aquaporin-2 and glucose transporter 4 in polarized MDCK cells (2007)
  • Author(s): Hasegawa T, Matsuzaki T, Tajika Y, Ablimit A, Suzuki T, Aoki T, Hagiwara H & Takata K
  • Journal Title: Histochem Cell Biol 127(3) Pages: 233-241
  • Peer Reviewed
• [Journal Article] Immunolocalization of water channel aquaporins in the nasal olfactory mucosa (2006)
  • Author(s): Ablimit A, Matsuzaki T, Tajika Y, Aoki T, Hagiwara H & Takata K
  • Journal Title: Arch Histol Cytol 69 Pages: 1-12
  • Peer Reviewed
• [Journal Article] Aquaporin-2(AQP2) : Its intracellular compartment and trafficking (2006)
  • Author(s): Takata K
  • Journal Title: Cell Mol Biol 52 Pages: 34-39
  • Peer Reviewed
• [Presentation] Intracellular localization and trafficking of water channel aquaporin 2(AQP2). 9th Asia-Pacific Microscopy Conference (2008)
  • Author(s): Takata K
  • Organizer: Jeju(Symposium L-07 Recent Progress of Functional Morphology of the Kidney)
  • Place of Presentation: Korea
  • Year and Date: 20081102-07
• [Presentation] Localization and trafficking of aquaporin 2 in the kidney (2008)
  • Author(s): Takata K
  • Organizer: 50th Symposium of the Society for Histochemistry(Rober Feulgen Lecture 2008)
  • Place of Presentation: Interlaken, Switzerland
  • Year and Date: 20081001-04
• [Presentation] Intracelluar compartment of aquaporin-2(AQP2) and glucose transporter-4(GLUT4) in MDCK Cells (2007)
  • Author(s): Takata K, Hasegawa T, Matsuzaki T, Tajika Y, Ablimit A, Suzuki T, Aoki T & Hagiwara H
  • Organizer: The 5th International Conference of Aquaporin
  • Place of Presentation: Nara, Japan
  • Year and Date: 20070713-16
• [Presentation] Intracellular compartment and trafficking of aquaporin-2 water channel (2006)
  • Author(s): Takata K, Tajika Y, Matsuzaki T, Suzuki T, Aoki T, Hagiwara H
  • Organizer: The16th International Microscopy Congress
  • Place of Presentation: Sapporo, Japan
  • Year and Date: 20060903-20090908
• [Presentation] Internalization of caveolae and their relationship with endosomes (2006)
  • Author(s): Aoki T, Suzuki T, Matsuzaki T, Hagiwara H, Takata K
  • Organizer: The16th International Microscopy Congress
  • Place of Presentation: Sapporo, Japan
  • Year and Date: 20060903-20090908
• [Book] アクアポリンの分布(動物)からだと水の事典(佐々木成, 石橋賢一) (2008)
  • Author(s): 高田邦昭, 松崎利行
  • Total Pages: 57-64
  • Publisher: 朝倉書店(東京)
• [Book] 染色・バイオイメージング実験ハンドブック。細胞や組織の形態・遺伝子・タンパク質を観るための染色法と顕微鏡観察のすべて。実験医学別冊(高田邦昭, 斎藤尚亮, 川上速人) (2006)
  • Total Pages: 1-334
  • Publisher: 羊土社(東京)