2009 Fiscal Year Final Research Report
An intervention study for the arteriosclerosis prevention considering NOS genetic polymorphism in the occupational area group
| Project/Area Number |
18390180
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Hygiene
|
|---|
| Research Institution | Tottori University |
|---|
Principal Investigator |
KISHIMOTO Takuji Tottori University, 医学部, 教授 (00116394)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
OSAKI Yoneatsu 鳥取大学, 医学部, 准教授 (10325003)
OKAMOTO Mikizo 鳥取大学, 医学部, 講師 (40032205)
|
|---|
| Project Period (FY) |
2006 – 2009
|
| Keywords | 遺伝子 / 衛生 / 社会医学 / 循環器 / 高血圧 / 糖尿病 |
|---|
| Research Abstract |
Tendencies to brachial-ankle pulse wave velocity (baPWV) improvement were analyzed in subjects with a slight arteriosclerosis judged by baPWV in reporting group (weak intervention) and intervention group (strong intervention). In the reporting group, the significant improvement was not shown in both -786C allele carriers and non--786C allele carriers of the NOS T-786C genetic polymorphism. However, in the intervention group, a tendency to significant improvement was found in non--786C allele carriers. The effect by the intervention was suggested to be low in -786C allele carriers.
|
Research Products
(9 results)
