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2007 Fiscal Year Final Research Report Summary

Development of image diagnostic system for upper airway using high dimensional imaging data and Establishment of diagnostic standard criteria.

Research Project

Project/Area Number 18390501
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionTsurumi University

Principal Investigator

KOBAYASHI Kaoru  Tsurumi University, School of Dental Medicine, Department of Oral Radiology, Professor (50139614)

Co-Investigator(Kenkyū-buntansha) OGAWA Takumi  Tsurumi University, School of Dental Medicine, The Second Department of Prosthetic Dentistry, Assistant (20267537)
HAMADA Yoshiki  Tsurumi University, School of Dental Medicine, First Department of Oral and Maxillofacial Surgery, Lecturer (70247336)
Project Period (FY) 2006 – 2007
KeywordsDiagnostic Radiology / Obstructive sleep apnea(OSA)
Research Abstract

Obstructive sleep apnea (OSA) is a disorder characterized by repetitive upper airway collapse during sleep. Identifying the exact location of the obstruction is important to obtain an effective treatment. For many years 2-dimensional (2D) cephalometric images have been used to look for anatomic differences between OSA patients and normal subjects (non-OSA), and researchers have reported significant craniofacial differences such as size and position of the mandible, posterior airway space enlargement, and in the size of the tongue and soft palate. While 2D imaging is valuable, the complex shape of the airway is not fully appreciated except with 3D images and nature of the obstruction in obstructive sleep apnea (OSA) patients. Ten OSA patients and 10 non-OSA control subjects were imaged using conebeam computed tomography to compare their upper airway structure.
This project have four phases of following steps : 1. The systems construction of the high-dimensional image data, 2. The decision of the clinical item, 3. Examination of the diagnosis accuracy by the randomized controlled trial, 4. The establishment of the diagnostic criteria.
The following conclusions were provided about the OSA patients :
(1) we demonstrate the utility of diagnosis of anatomy with the 3D airway imaging with CBCT in awake patients in the supine position ; (2) we show the characteristics of OSA airway that may contribute to distinguishing OSA cases from non-OSA cases.

  • Research Products

    (29 results)

All 2008 2007 2006

All Journal Article (14 results) (of which Peer Reviewed: 7 results) Presentation (15 results)

  • [Journal Article] Changes in three dimensional simulation models of the airway which are due to increases in age or body mass index2008

    • Author(s)
      Shigeta Y, Enciso R, Ogawa T, et. al.
    • Journal Title

      Stud Health Technol Inform 132

      Pages: 460-462

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Correlation between retroglossal airway size and body mass index in OSA and non-OSApatients using cone beam CT imaging2008

    • Author(s)
      Yuko Shigeta, Reyes Enciso, Takumi Ogawa, et. al.
    • Journal Title

      Sleep Breath DOI:10.1007/s11325-008-0186-62008(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Cervical CT derived neck fat tissue distribution differences in Japanese males and females and its effect on retroglossal and retropalatal airway volume2008

    • Author(s)
      Yuko Shigeta, Reyes Enciso, Takumi Ogawa, et. al.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod DOI:10.1016/j.tripleo

      Pages: 275-284

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Gender and age-based differences in computed-tomography measurements of the orophaynx2008

    • Author(s)
      Yuko Shigeta, Takumi Ogawa, Jaqueline Venturin, et. al.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod DOI:10.1016/j.tripleo(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] The influence of age and BMI on interverfebral disc height and oropharyngeal airway in Japanese men and women2008

    • Author(s)
      Yuko Shigeta, Takumi Ogawa, Jaqueline Venturin, et. al.
    • Journal Title

      Int J CARS DOI:10.1007/s11548-008-0204-y(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Changes in three dimensional simulation models of the airway which are due to increases in age or body mass index.2008

    • Author(s)
      Shigeta Y, Enciso R, Ogawa T, Clark GT.
    • Journal Title

      Stud Health Technol Inform 132

      Pages: 460-462

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Correlation between retroglossal airway size and body mass index in OSA and non-OSA patients using cone beam CT imaging.2008

    • Author(s)
      Shigeta Y, Enciso R, Ogawa T, Shintaku WH, Clark GT.
    • Journal Title

      Sleep Breath DOI : 10.1007/s11325-008-0186-62008

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Cervical CT derived neck fat tissue distribution differences in Japanese males and females and its effect on retroglossal and retropalatal airway volume.2008

    • Author(s)
      Yuko Shigeta, Reyes Enciso, Takumi Ogawa, Tomoko Ikawa, Glenn T Clark
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod DOI : 10.1016/j.tripleo

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Gender and age-based differences in computed-tomography measurements of the orophaynx.2008

    • Author(s)
      Yuko Shigeta, Takumi Ogawa, Jaqueline Venturin, Manuel Nguyen, Glenn T Clark, Reyes Enciso.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod DOI : 10.1016/j.tripleo.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] The influence of the soft palate to the upper airway space in OSA and non-OSA subjects.2008

    • Author(s)
      Yuko Shigeta, Takumi Ogawa, Ikawa Tomoko, Glenn T Clark, Reyes Enciso.
    • Journal Title

      Sleep Breath DOI : DOI : 10.1007/s11548-008-0204-y

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Evaluation of Cross-section Airway Configuration of Obstructive Sleep Apnea2007

    • Author(s)
      Takumi Ogawa, Reyes Enciso, Werner H.Shintaku, et. al.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103(1)

      Pages: 102-108

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Upper airway alterations/abnormalities in a case series of obstructive sleep apne a patients identified with cone-beam CT2007

    • Author(s)
      Y.Shigeta, R.Enciso, T.Ogawa, et. al.
    • Journal Title

      International Journal of Computer Assisted Radiology and Surgery 2(1)

      Pages: 402-404

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Shintaku, Glenn T Clark. Evaluation of Cross-section Airway Configuration of Obstructive Sleep Apnea.2007

    • Author(s)
      Takumi Ogawa, Reyes Enciso, Werner H.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103(1)

      Pages: 102-108

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Upper airway alterations/abnormalities in a case series of obstructive sleep apnea patients identified with cone-beam CT.2007

    • Author(s)
      Y. Shigeta, R. Enciso, T. Ogawa, W.H. Shintaku, G.T. Clark.
    • Journal Title

      Int J CARS 2(1)

      Pages: 402-404

    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Changes in three dimensional simulation models of the airway which are due to increases in age or body mass index.2008

    • Author(s)
      Shigeta Y, Enciso R, Ogawa T, Clark GT.
    • Organizer
      The 16th Annual Medicine Meets Virtual Reality Conference
    • Place of Presentation
      The Hyatt Regency Long Beach, California,. U.S.A.
    • Year and Date
      20080230
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Changes in three dimensional simulation models of the airway which are due to increases in age or body mass index2008

    • Author(s)
      Yuko Shigeta
    • Organizer
      The 16th Annual Medicine Meets Virtual Reality Conference.
    • Place of Presentation
      The Hyatt Regency Long Beach,California,U.S.A.
    • Year and Date
      2008-01-30
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 鶴見大学「いびき外来」における睡眠時無呼吸症候群への対応2008

    • Author(s)
      小川 匠
    • Organizer
      補綴学会 西関東支部
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-01-13
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 鶴見大学「いびき外来」で応用している鶴見型OAの紹介2008

    • Author(s)
      森井 和希
    • Organizer
      補綴学会 西関東支部
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-01-13
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 鶴見大学歯学部「いびき外来」における睡眠時無呼吸症候群に対するスプリント治療の現状2008

    • Author(s)
      石川 千恵子
    • Organizer
      神奈川県歯科医師会 学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-01-13
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] The Oral Appliance Therapy with OSA Patient Using X-ray Image2007

    • Author(s)
      Takumi Ogawa
    • Organizer
      International College of Prosthodontists
    • Place of Presentation
      JAL Resort Sea Hawk Hotel,福岡
    • Year and Date
      2007-09-06
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] The Oral Appliance Therapy with OSA Patient Using X-ray Image2007

    • Author(s)
      Ogawa T, Shigeta Y, Ikawa T, Ando E., Hirai S, Fukushima S, Ishikawa T, Hosoi N, Mizuno Y, Morii K, Ihara K, Kawamura N, Hamada Y, Suzuki M, Seto K, Nejima J.
    • Organizer
      The 12th International College of Prosthodontists
    • Place of Presentation
      JAL Resort Sea Hawk Hotel, Fukuoka, Japan
    • Year and Date
      2007-09-06
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Upper airway alterations/abnormalities in a case series of obstructive sleep apnea patients identified with cone-beam CT2007

    • Author(s)
      Yuko Shigeta
    • Organizer
      Computer Assisted Radiology and Surgery
    • Place of Presentation
      International Congress Center,Berlin,Germany
    • Year and Date
      2007-06-28
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Upper airway alterations/abnormalities in a case series of obstructive sleep apnea patients identified with cone-beam CT.2007

    • Author(s)
      Yuko Shigeta, Reyes Enciso, Takumi Ogawa, Werner H. Shintaku, Glenn T. Clark.
    • Organizer
      Computer Assisted Radiology and Surgery 21st International Congress and Exhibition
    • Place of Presentation
      International Congress Center, Berlin, Germany
    • Year and Date
      2007-06-28
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] The Establishment of the Snoring and OSA Clinic in Tsurumi UNIV.School of Dental Medicine2007

    • Author(s)
      Chieko Ishikawa
    • Organizer
      日本補綴歯科学会学術大会
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2007-05-20
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] The Establishment of the Snoring and OSA Clinic in Tsurumi UNIV. School of Dental Medicine.2007

    • Author(s)
      Chieko Ishikawa, Takumi Ogawa, Tomoko Ikawa, Shinya Hirai, Yuko Shigeta, Yukihiro Mizuno, Noboru Kawamura, Kazuki Morii, Keisuke Ihara, Toshio Hosoi, Syunji Fukushima, Jun Nejima.
    • Organizer
      The 116th Scientific Meeting of Japan Prosthodontic Society.
    • Place of Presentation
      Kobe Portopia Hotel, Kobe, Japan
    • Year and Date
      2007-05-20
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Effectiveness of high dimensional CT imaging of obstructive sleep apnea and temporomandibular disorders patients2006

    • Author(s)
      Kaoru Kobayashi
    • Organizer
      The 6th Asian Congress of Oral and Maxillo-Facial Radiology & XVII National Conference of Indian Academy of Oral Medicine & Radiology.
    • Place of Presentation
      J.N.Tara Auditorium,Bangalore,India.
    • Year and Date
      2006-12-09
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Effectiveness of high dimensional CT imaging of obstructive sleep apnea and temporomandibular disorders patients.2006

    • Author(s)
      Kaoru Kobayashi, Special lecture
    • Organizer
      The 6th Asian Congress of Oral and Maxillo-Facial Radiology & X VIII National Conference of Indian Academy of Oral Medicine & Radiology.
    • Place of Presentation
      J.N. Tara Auditorium, Bangalore, India
    • Year and Date
      2006-12-09
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] 附属病院いびき外来の現状2006

    • Author(s)
      子島 潤
    • Organizer
      鶴見大学歯学会
    • Place of Presentation
      鶴見大学会館,横浜
    • Year and Date
      2006-07-15
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] いびき外来におけるOral appliance治療の実際2006

    • Author(s)
      石川 千恵子
    • Organizer
      鶴見大学歯学会
    • Place of Presentation
      鶴見大学会館,横浜
    • Year and Date
      2006-07-15
    • Description
      「研究成果報告書概要(和文)」より

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Published: 2010-02-04  

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