• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2008 Fiscal Year Final Research Report

High Performance Ti implant by photo-immobilization of cytokine and its effect oncell adhesion, proliferation and differentiation

Research Project

  • PDF
Project/Area Number 18390513
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field 補綴理工系歯学
Research InstitutionOkayama University

Principal Investigator

YOSHIDA Yasuhiro  Okayama University, 大学院・医歯薬学総合研究科, 准教授 (90281162)

Co-Investigator(Kenkyū-buntansha) SUZUKI Kazuomi  岡山大学, 大学院・医歯薬学総合研究科, 教授 (30050058)
YAMAMOTO Toshio  岡山大学, 大学院・医歯薬学総合研究科, 教授 (30107776)
NAGAOKA Noriyuki  岡山大学, 大学院・医歯薬学総合研究科, 教授 (70304326)
ITO Yoshihiro  理化学研究所, 伊藤ナノ医工学研究室, 研究員 (40192497)
Project Period (FY) 2006 – 2008
Keywords歯科理工学 / 歯科材料学 / 生体材料学 / 歯科インプラント学 / サイトカイン / チタン / 光固定
Research Abstract

インプラント周囲の組織再生能を向上すべく、様々な表面改質法が考案されている.しかし生体分子の固定化に関しては、未だ実用的な手法は報告されていない.本研究では、光反応性ゼラチンによるチタン表面への生体分子固定化法を新たに開発し、その結果、チタン表面にゼラチンを微細構造状に光固定化できることが明らかとなった.様々な生体分子を共固定化することにより、チタン表面への生体機能性付与が可能となると期待される.

  • Research Products

    (20 results)

All 2009 2008 2007 2006 Other

All Journal Article (13 results) Presentation (6 results) Remarks (1 results)

  • [Journal Article] Polyphosphoric acid treatment promotes bone formation around titanium implants2009

    • Author(s)
      Maekawa, K., Shimono, K., Oshima, M., Yoshida, Y., Van Meerbeek, B., Suzuki, K., Kuboki, T.
    • Journal Title

      Journal of Oral Rehabilitation 36

      Pages: 362-367

  • [Journal Article] Antibacterial effect of baresin matrix2009

    • Author(s)
      Namba, N., Yoshida, Y., Nagaoka, N., Takashima, S., Matsuura-Yoshimoto, K., Maeda, H., Van Meerbeek, B., Suzuki, K., Takashiba, S.
    • Journal Title

      Dental Materials 25

      Pages: 424-430

  • [Journal Article] Effect of polyphosphoric-acid pre-treatment of titanium on attachment, proliferation and differentiation of osteoblast like cells(MC3T3-E1)2008

    • Author(s)
      Maekawa, K., Yoshida, Y., Mine, A., Van Meerbeek, B., Suzuki, K., Kuboki, T.
    • Journal Title

      Clinical Oral Implants Research 19

      Pages: 320-325

  • [Journal Article] Promotion of hydroxyapatite-associated, stem cells-based bone regeneration by CCN22008

    • Author(s)
      Ono, M., Kubota, S., Fujisawa, T., Sonoyama, W., Kawaki, H., Akiyama, K., Oshima, M., Nishida, T., Yoshida, Y., Suzuki, K., Takigawa, M., Kuboki, T.
    • Journal Title

      Cell Transplantation 17

      Pages: 231-240

  • [Journal Article] Influence of the chemical structure of functional monomers on their adhesive performance2008

    • Author(s)
      Van Landuyt, K.L., Yoshida, Y., Hirata, I., Snauwaert, J., De Munck, J., Okazaki, M., Suzuki, K., Lambrechts, P., Van Meerbeek, B.
    • Journal Title

      Journal of Dental Research 87

      Pages: 757-761

  • [Journal Article] Modification of the titan surface with photoreactive gelatin to regulate cell attachment2007

    • Author(s)
      Heydari, M., Hasuda, H., Sakuragi, M., Yoshida, Y., Suzuki, K., Ito, Y.
    • Journal Title

      Journal of Biomedical Materials Research : Part A 83

      Pages: 906-914

  • [Journal Article] Chemical interaction of polyphosphoric acid with titanium and its effect on human bone marrow derived mesenchymal stem cell behavior2007

    • Author(s)
      Maekawa, K., Yoshida, Y., Mine, A., Fujisawa, T., Van Meerbeek, B., Suzuki, K., Kuboki, T.
    • Journal Title

      J Materials Research : Part A 82A

      Pages: 195-200

  • [Journal Article] Promotion of attachment of human bone marrow stromal cells by CNN22007

    • Author(s)
      Ono, M., Kubota, S., Fujisawa, T., Sonoyama, W., Kawaki, H., Akiyama, K.,Oshima, M., Nishida, T., Yoshida, Y., Suzuki, K., Takigawa, M., Kuboki, T.
    • Journal Title

      Biochemical and Biophysical Research Communications 357

      Pages: 20-25

  • [Journal Article] Gel phase formation at resin-modified glass-ionomer/tooth interfaces2007

    • Author(s)
      Coutinho, E., Yoshida, Y., Inoue, S., Fukuda, R., Snauwaert, J., Nakayama, Y., De Munck, J., Lambrechts, P., Suzuki, K., Van Meerbeek, B.
    • Journal Title

      Journal of Dental Research 86

      Pages: 656-661

  • [Journal Article] Origin of interfacial droplets self-etch adhesives2007

    • Author(s)
      Van Landuyt, K.L., Snauwaert, J., De Munck, J., Coutinho, E., Poitevin, A., Yoshida, Y., Suzuki, K., Lambrechts, P., Van Meerbeek. B.
    • Journal Title

      Journal of Dental Research 86

      Pages: 739-744

  • [Journal Article] Effect of 4-MET-and 10-MDP-based priresin bonding to titanium2006

    • Author(s)
      Tsuchimoto, Y., Yoshida, Y., Mine, A., Nakamura, M., Nishiyama, N., Van Meerbeek, B., Suzuki, K
    • Journal Title

      Dental Materials Journal 25

      Pages: 120-124

  • [Journal Article] Effect of surface pre-treatment on durability of resin-based cements bonded to titanium2006

    • Author(s)
      Tsuchimoto, Y., Yoshida, Y., Takeuchi, M., Mine, A., Yatani, H., Tagawa, Y., Van Meerbeek, B., Suzuki, K., Kuboki, T.
    • Journal Title

      Dental Materials 22

      Pages: 545-552

  • [Journal Article] Chemical interaction of phosphoric acid ester with hydroxyapatite2006

    • Author(s)
      Fukegawa, D., Hayakawa, S., Yoshida, Y., Suzuki, K., Osaka, A.,Van Meerbeek, B.
    • Journal Title

      Journal of Dental Research 85

      Pages: 941-944

  • [Presentation] Strates to create the super tooth2009

    • Author(s)
      Yoshida, Y.
    • Organizer
      Nano-interfacial control for functional reconstruction of human hard tissues Global Center of Excellence Program ; International Research Center for Molecular Science in Tooth and Bone Diseases : G-COE 1st International Symposium
    • Place of Presentation
      Tokyo Gakusei Kaikan, Tokyo, Japan
    • Year and Date
      2009-01-22
  • [Presentation] Tissue-Biomaterial Interface Research for Prosthodontic Dentistry2008

    • Author(s)
      Yoshida, Y.
    • Organizer
      Interfacial control for functional reconstruction of human hard tissues. The International Symposium of the 117th Scientific Meeting of Japan Prosthodontic Society in Nagoya, The International Congress of Prosthodontics 2008 in Nagoya, The 1st Biennial Joint Congress of Chinese Prosthodontic Society, Japan Prosthodontic Society and Korean Academy of Prosthodontics
    • Place of Presentation
      Nagoya Congress Center, Nagoya, Japan
    • Year and Date
      20080606-08
  • [Presentation] Nano-interfacial control for hard tissue reconstruction.2007

    • Author(s)
      Yoshida, Y.
    • Organizer
      The Annual Scientific Meeting of the Association for Dental Sciences of the Republic of China
    • Place of Presentation
      The TaiPei International Convention Center, Taipei, Taiwan.
    • Year and Date
      20071116-18
  • [Presentation] Surface modification of Ti implants for promotion of bone regeneration2007

    • Author(s)
      Yoshida, Y., Suzuki, K.
    • Organizer
      The 6th International Symposium on Titanium in Dentistry. International Conference Center
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      20070605-06
  • [Presentation] Nano-interfacial control for functional reconstruction of human hard tissues. The 9th International Symposium on Biomimetic Interfaces2007

    • Author(s)
      Yoshida, Y.
    • Organizer
      Recent trends of nanobiotechnology in medical and dental research
    • Place of Presentation
      Seoul National University, Seoul, Korea
    • Year and Date
      2007-02-01
  • [Presentation] 光反応性ゼラチンによるチタン表面の生物学的改質2006

    • Author(s)
      吉田靖弘, 鈴木一臣
    • Organizer
      第48回日本歯科理工学会学術講演会
    • Place of Presentation
      名古屋
    • Year and Date
      20061028-29
  • [Remarks] 第48回日本歯科理工学会学術講演会発表優秀賞(2007年)

URL: 

Published: 2010-06-10   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi