2007 Fiscal Year Final Research Report Summary
Intensive training for unilateral spatial neglect with repetitive transcranial magnetic stimulation
| Project/Area Number |
18500412
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kagoshima University |
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Principal Investigator |
OGATA Atsuko Kagoshima University, Graduate School of Medical and Dental Sciences, Assistant Professor (40305123)
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| Co-Investigator(Kenkyū-buntansha) |
ETOH Seiji Kagoshima University, Medical and Dental Hospital, Senior Assistant Professor (70295244)
KAWAHIRA Kazumi Kagoshima University, Graduate School of Medical and Dental Sciences, Professor (20117493)
SHIMODOZONO Megumi Kagoshima University, Graduate School of Medical and Dental Sciences, Associate Professor (30325782)
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| Project Period (FY) |
2006 – 2007
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| Keywords | unilateral spatial neglect / transcranial magnetic stimulation / reaching task / stroke / BIT |
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| Research Abstract |
The aim of the study was to investigate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected hemisphere and a computerized reaching task can ameliorate visuospatial neglect in stroke patients.
The subjects were 3 patients with left unilateral spatial neglect (USN) with stroke. Neurological examination showed contralateral hemiparesis and contralateral visuospatial neglect assessed by Behavioural Inattention Test (BIT) and a computerized simple and delayed reaction time. The experimental schedule consisted of rTMS and reaching task sessions delivered 10 days for two consecutive weeks. Each session consisted of one train of 300 pulses delivered at 90% of motor threshold by means of a focal eight-shaped coil placed over P5 (according to the EEG 10/20 system) and simple and delayed computerized reaching task (20-30 min). Patients tolerated rTMS treatment well and no adverse events were reported.
rTMS and reaching task induced an improvement of visuospatial performance. Our data need to be confirmed in larger series by controlled studies.
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