2007 Fiscal Year Final Research Report Summary
Development of interventional program in health education for pre-diabetes mellitus
| Project/Area Number |
18500628
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Yamaguchi Prefectural University |
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Principal Investigator |
NOGI Akiko Yamaguchi Prefectural University, Facultyu of Nursing and Human Nutrition, Clinical Nutrition, Associate Prof. (90312305)
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| Co-Investigator(Kenkyū-buntansha) |
SHIWAKU Kuninori Shimane University College of Medicine, Environmental Medicine, Lecturer (10108384)
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| Project Period (FY) |
2006 – 2007
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| Keywords | Pre-diabetes mellitus / Obesity / Insulin resistance / IGT / OGTT / Diet / Exercise |
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| Research Abstract |
Since the prevalence of diabetes mellitus are getting increase in Japanese; we conducted to develop an intervention al program for obesity based on health education and self-determination from 2000. We adopted the behavioral program to strengthen self-control of diet and exercise based on learning principles. Objectives of the program were to lose 1.0kg of weight and to reduce 10% of metabolic measurement values.
Subjects were 123 residents with Body Mass. Index (BMI) of 26.1± 3.2, aged 57.2±8.1 years in Shimane Prefecture, voluntarily participated in the present study in 2006-2007. The behavioral intervention induced significant decrease s for intakes of energy (-483kcal, -22%), and increase for consumption of energy (146kcal, 6%) per day for participants. The intervention induced a significant difference in weight-loss (-2.8kg). Significant differences of anthropometric parameters were found in BMI (4.2%), waist circumference (4.2%), systolic blood pressure (2.9%), and lipid profile, such as total cholesterol (5.1%), triglyceride (22.0%) by the intervention. For participants.
The participant numbers identified oral glucose tolerance test (OGTT) changed by the intervention, non glucose tolerance (NGT) increased (n=57 to 79), impaired fasting glucose (IFG) increased(n=6 to 11), impaired glucose tolerance (IGT) decreased(n=29 to 14), IFG+IGT increased (n=8 to 9) and type 2 diabetes mellitus (T2DM) decreased (n=14 to 10). Individuals with JOT showed significant differences in 2-h glucose (161mg/dl to 135mg/dl) and 30-min insulin (42.8μU/ml to 48.0μU/ml). also T2DM showed significant differences in homeostasis model assessment (HOMA-IR) (2.3 to L4), 30-min glucose (265mg/dl to 223mg/dl) and 2-h glucose (253mg/dl to 189mg/dl).
This investigation suggests that the interventional program have an improvement of insulin resistance and an effect on early treatment for pre-diabetes mellitus.
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[Journal Article] Predictive values of anthropometric measurements for visceral obesity and metabolic syndrome in educational intervention(In Japanese)2008
Author(s)
Limei, LI, Rumi, IKENISHI, Mamiko, IWAMOTO, Akiko, NOGI, Masayuki, YAMASAKI, Li, WANG, Toshimi, YONEYAMA, Kuninori, SHIWAKU
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Journal Title
J JPN Assoc Rural Med 56
Pages: 852-862
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Concept and countermeasures of metabolic syndrome(In Japanese)2007
Author(s)
Kuninori, SHIWAKU, Masayuki, YAMASAKI, Mamiko, IWAMOTO,(WATANABE), Rumi, IKENISHI, Toshimi, YONEYAMA, Limei, LI, Li, WANG, Akiko, NOGI
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Journal Title
J JPN Assoc Rural Med 58
Pages: 605-617
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Predictive values of anthropometric measurements for visceral obesity and metabolic syndrome in educational intervention2008
Author(s)
Nogi A, Iwamoto M, Ikenishi R, Limei, Li, Wang, Li, Yamasaki M, Shiwaku, K
Organizer
XVIII World Congress on Safety and Health at Work(発表予定)
Place of Presentation
Soeul, Korea
Year and Date
20080600
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Visceral obesity and insulin resistance in Japanese with metabolic syndrome or type 2 diabetes2007
Author(s)
Shiwaku K, Yamasakia M, Watanabea M, Nogi A, Yang J, Li L, Wang L, Nabika T, Masuda J, Yamaguchi, S
Organizer
2nd International Congress on "Prediabetes" and the Metabolic Syndrome
Place of Presentation
Barcelona, Spain
Year and Date
20070400
Description
「研究成果報告書概要(欧文)」より
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