2009 Fiscal Year Final Research Report

Preventive effect of powdered green tea and exercise on Postmenopausal osteoporosis

Research Project

Project/Area Number	18500631
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Eating habits, studies on eating habits
Research Institution	Gifu Women's University
Principal Investigator	HASEGAWA Noboru Gifu Women's University, 家政学部, 教授 (10156317)
Co-Investigator(Kenkyū-buntansha)	MOCHIZUKI Miyako 岐阜女子大学, 家政学部, 助手 (20367858)
Project Period (FY)	2006 – 2009
Keywords	粉末緑茶 / カテキン / 更年期 / 骨粗鬆症 / 運動負荷
Research Abstract	We studied the protective effect of EGCG on bone loss in ovariectomized (OVX) rats. Ovariectomy significantly decreased femur bone strength. Supplementation of EGCG suppressed bone loss induced by OVX and osteoclastogenesis in RAW264.7. We recruited eleven postmenopausal women, age 60-80. These women were given a daily EGCG tablet for 3 months. At 56 days, the SOS rate tended to increase as expected in the supplemented group. These observations confirmed that EGCG can prevent postmenopausal bone loss.

(3 results)