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2009 Fiscal Year Final Research Report

Qualitative theory of differential equations describing dynamics of infectious disease

Research Project

  • PDF
Project/Area Number 18540122
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General mathematics (including Probability theory/Statistical mathematics)
Research InstitutionOkayama University

Principal Investigator

SASAKI Toru  Okayama University, 大学院・環境学研究科, 准教授 (20260664)

Co-Investigator(Kenkyū-buntansha) KAJIWARA Tsuyoshi  岡山大学, 大学院・環境学研究科, 教授 (50169447)
Project Period (FY) 2006 – 2009
Keywords応用数学 / 微分方程式 / 関数方程式 / 感染症
Research Abstract

We obtained some results on qualitative properties of differential equation models describing the dynamics of infectious agents in a host. Here we dealt with the interaction among viruses, target cells, infected cells, and immunity. We showed for some models that the interior equilibrium, which corresponds to the infected state, is, under some conditions, globally asymptotically stable. In this connection, we considered some mathematical models of immunity, and established some properties of systems of differential equations describing autoimmunity.

  • Research Products

    (10 results)

All 2009 2008 2007 2006 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (4 results) Book (2 results)

  • [Journal Article] Dynamical properties of autoimmune disease models: Tolerance, flare-up, dormancy2007

    • Author(s)
      Shingo Iwami, Yasuhiro Takeuchi, Yoshiharu Miura, Toru Sasaki, Tsuyoshi Kajiwara
    • Journal Title

      J. theor. Biol. 246

      Pages: 646-659

    • Peer Reviewed
  • [Journal Article] Global dynamics of B cells and anti-idiotipic B cells and its application to autoimmunity2007

    • Author(s)
      Toru Sasaki, Tsuyoshi Kajiwara
    • Journal Title

      Japan Journal of Industrial and Applied Mathematics 24No.1

      Pages: 105-118

    • Peer Reviewed
  • [Journal Article] Global stability of models of humoral immunity against multiple viral strains

    • Author(s)
      Toru Inoue, Tsuyoshi Kajiwara, Toru Sasaki
    • Journal Title

      Journal of Biological Dynamics

      Pages: DOI: 10. 1080/17513750903180275

    • Peer Reviewed
  • [Journal Article] Global stability of pathogen-immune dynamics with absorption

    • Author(s)
      Tsuyoshi Kajiwara, Toru Sasaki
    • Journal Title

      Journal of Biological Dynamics

      Pages: DOI: 10. 1080/17513750903051989

    • Peer Reviewed
  • [Presentation] 免疫数理モデルの安定性2009

    • Author(s)
      梶原毅
    • Organizer
      日本数理生物学会年会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-09
  • [Presentation] 感染症ダイナミクスの安定性解析2008

    • Author(s)
      佐々木徹
    • Organizer
      日本応用数理学会オーガナイズドセッション
    • Place of Presentation
      柏
    • Year and Date
      2008-09-19
  • [Presentation] Mathematical models describing autoimmunity2007

    • Author(s)
      Toru Sasaki
    • Organizer
      International Symposium on Dynamical Systems Theory and Its Applications
    • Place of Presentation
      浜松
    • Year and Date
      2007-03-14
  • [Presentation] Global behavior of a B model incorporating autoimmunity2006

    • Author(s)
      Toru Sasaki
    • Organizer
      Japanese-Korean Joint Meeting for Mathematical Biology (第16回日本数理生物学会大会)
    • Place of Presentation
      福岡
    • Year and Date
      2006-09-16
  • [Book] 感染症の数理モデル2008

    • Author(s)
      稲葉寿編著
    • Total Pages
      125-138
    • Publisher
      培風館
  • [Book] 数の数理生物学2008

    • Author(s)
      日本数理生物学会編集
    • Total Pages
      92-100
    • Publisher
      共立出版

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Published: 2011-06-18   Modified: 2016-04-21  

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