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2008 Fiscal Year Final Research Report

The study on biological roles of N-linked protein glycosylation system in Campylobacter

Research Project

  • PDF
Project/Area Number 18580312
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied veterinary science
Research InstitutionKitasato University

Principal Investigator

KAKUDA Tsutomu  Kitasato University, 獣医学部, 准教授 (80317057)

Co-Investigator(Kenkyū-buntansha) TAKAI Shinji  北里大学, 獣医学部, 教授 (80137900)
Project Period (FY) 2006 – 2008
Research Abstract

カンピロバクター・ジェジュニは食中毒の起因菌である。近年、このカンピロバクターが蛋白のN結合型糖鎖修飾システムを有していることが明らかとなった。N結合型糖鎖修飾システムは菌の病原性に影響を与えることが知られているもののそのメカニズムは不明である。我々は、N-結合型糖鎖修飾を受けた蛋白を同定し、糖鎖が修飾を受ける蛋白の機能等に与える影響を調べた。その過程で、本菌の糖蛋白の中には糖鎖が蛋白の機能に明瞭な影響を有しないものが存在することが明らかとなった

  • Research Products

    (8 results)

All 2009 2008 2007 2006

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (2 results)

  • [Journal Article] A Campylobacter jejuni znuA orthologue isessential for growth in low-zincenvironments and chick colonization2009

    • Author(s)
      Davis LM, Kakuda T, DiRita VJ.
    • Journal Title

      J Bacteriol 191(5)

      Pages: 1631-40

    • Peer Reviewed
  • [Journal Article] Isolation and characterisation of Rhodococcus equi from submaxillary lymphnodes of wild boars(Sus scrofa)2008

    • Author(s)
      Makrai L, Kobayashi A, Matsuoka M
    • Journal Title

      Vet Microbiol 15 ; 131(3-4)

      Pages: 318-23

    • Peer Reviewed
  • [Journal Article] Genotypic characterization of VapA positive Rhodococcus equi in foals withpulmonary affection and their soilenvironment on a warmblood horse breedingfarm in Germany2007

    • Author(s)
      Venner M, Meyer-Hamme B, Verspohl J
    • Journal Title

      Res Vet Sci. 83(3)

      Pages: 311-7

    • Peer Reviewed
  • [Journal Article] Rhodococcus equi in the soil environment of horses in Inner Mongolia, China2006

    • Author(s)
      Takai S, Zhuang D, Huo XW, Madarame H
    • Journal Title

      J Vet Med Sci. 68(7)

      Pages: 739-42

    • Peer Reviewed
  • [Journal Article] Filamentous-haemagglutinin-like protein genes encoded on a plasmid of Moraxellabovis2006

    • Author(s)
      Kakuda T, Sarataphan N, Tanaka T, Takai S.
    • Journal Title

      Vet Microbiol 118(1-2)

      Pages: 141-7

    • Peer Reviewed
  • [Journal Article] Cj1496c encodes a Campylobacter jejuni glycoprotein that influences invasion ofhuman epithelial cells and colonization ofthe chick gastrointestinal tract2006

    • Author(s)
      Kakuda T, DiRita VJ.
    • Journal Title

      Infect Immun 74(8)

      Pages: 4715-23

    • Peer Reviewed
  • [Presentation] Campylobacter jejuniによるバイオフィルム形成のメカニズムの解明微生物アカデミー学術研究集会2007

    • Author(s)
      角田勤
    • Place of Presentation
      東京
    • Year and Date
      20071200
  • [Presentation] Campylobacterjejuniの自己凝集/バイオフィルム形成関連遺伝子の検索第2007

    • Author(s)
      清水奈菜子( 角田勤)
    • Organizer
      61回日本細菌学会東北支部会
    • Place of Presentation
      福島市
    • Year and Date
      20070800

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Published: 2010-06-10   Modified: 2016-04-21  

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