Neural Mechanism of sexual orientation in the male and female rat brain

2008 Fiscal Year Self-evaluation Report

• Project/Area Number: 18590225
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Environmental physiology (including Physical medicine and Nutritional physiology)
• Research Institution: Nippon Medical School
• Principal Investigator: KONDO Yasuhiko Nippon Medical School, 医学部, 講師 (00192584)
• Project Period (FY): 2006 – 2009
• Keywords: 性行動 / 性分化 / 生殖 / 性指向性 / 哺乳類

Research Abstract

雄の動物は雌を性パートナーとして選択し、雌の動物は雄を選ぶ。この性指向性を決定している神経回路を探ることを目的とする。

Research Products

• [Journal Article] 性指向性の決定機構 (2009)
  • Author(s): 近藤保彦・佐久間康夫
  • Journal Title: Clinical Neuroscience
• [Journal Article] 性的動機づけ(性欲)評価のための動物実験 (2008)
  • Author(s): 近藤保彦
  • Journal Title: アニテックス 20 Pages: 18-22
• [Journal Article] 幼若期の生育環境と性衝動-動物モデルからの検討 (2008)
  • Author(s): 近藤保彦
  • Journal Title: 現代性教育研究月報 26 Pages: 8-9
• [Journal Article] Transient transcription of the somatostatin gene at the time of estrogen-dependent organization of the sexually dimorphic nucleus of the rat preoptic area (2007)
  • Author(s): Orikasa, C., Kondo, Y. and Sakuma, Y.
  • Journal Title: Endocrinology 148 Pages: 1144-1149
  • Peer Reviewed
• [Journal Article] Dehydroepi-androsterone alleviates copulatory disorder induced by social stress in male rats (2006)
  • Author(s): Mizuno, T., Yotsuyanagi, S., Kondo, Y., Komatsu, K., Ishiura, Y., Nakamura, Y., Nagasaka, Y., Yokoyama, O. and Namiki, M.
  • Journal Title: Journal of Sexual Medicine(Erratum : Journal of Sexual Medicine 3 : 1090, 2006) 3 Pages: 612-618
  • Peer Reviewed
• [Presentation] 他個体の社会信号受容に影響する心理学的因子 (2008)
  • Author(s): 近藤保彦
  • Organizer: 日本心理学会第72回大会シンポジウム「こころに作用するホルモン」
  • Place of Presentation: 札幌
  • Year and Date: 20080000
• [Presentation] 雄マウスの交尾時超音波発声の発達におけるオキシトシンの役割 (2008)
  • Author(s): 近藤保彦・佐伯知香・高橋弥生・田中実・西森克彦・齊藤徹・佐久間康夫
  • Organizer: 日本動物心理学会第68回大会
  • Place of Presentation: 水戸
  • Year and Date: 20080000
• [Presentation] Sex difference in hormonal and neural regulation of olfactory preference for conspecifics in the rat (2008)
  • Author(s): Kondo, Y. and Sakuma, Y.
  • Organizer: The physiological society of Japan Symposium for "New perspectives on hormonal bases of reproductive behavior."
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 20080000
• [Presentation] Male rat sexual preference can be revered by estrogen action in adults (2008)
  • Author(s): Kondo, Y. and Sakuma, Y.
  • Organizer: Session 7 : Steroid Hormones and Sex Differences in Brain and Behavior. US/JAPAN Neurosteroid Symposium 2008
  • Place of Presentation: Gifu, Japan
  • Year and Date: 20080000
• [Presentation] Factors in recipient for chemosensory communication of rodent (2008)
  • Author(s): Kondo, Y.
  • Organizer: JAPAN/CHINA Joint Symposium for "Strategies to Reduce Risks on the Brain Development Contingent to Urbanization"
  • Place of Presentation: Tsukuba, Japan
  • Year and Date: 20080000
• [Presentation] セロトニン神経と雄性行動 (2008)
  • Author(s): 近藤保彦
  • Organizer: 第2回日本医科大学・早稲田大学 共催シンポジウム「セロトニンと人間」
  • Year and Date: 20080000
• [Presentation] Oxytocin is required for developing ultrasonic vocalization in mouse mating (2008)
  • Author(s): Kondo, Y., Saeki, T., Takahashi, Y., Tanaka, M., Nishimori, K., Saito, T.R. and Sakuma, Y.
  • Organizer: Society for Behavioral Neuroendocrinology
  • Place of Presentation: Groningen, Netherland
  • Year and Date: 20080000
• [Presentation] Generation of the somatostatin neurons in the sexually dimorphic nucleus of the rat preoptic area (2008)
  • Author(s): Orikasa, C., Kondo, Y., Urakawa, S., Usui, S. and Sakuma, Y.
  • Organizer: Society for Behavioral Neuroendocrinology
  • Place of Presentation: Groningen, Netherland
  • Year and Date: 20080000
• [Presentation] Conspecific olfactory preferences of male rats carrying lesions of the medial amygdala or the preoptic area (2008)
  • Author(s): Dhungel, S., Kondo, Y. and Sakuma, Y.
  • Organizer: Poster Session in US/JAPAN Neurosteroid Symposium 2008
  • Place of Presentation: Gifu, Japan
  • Year and Date: 20080000
• [Presentation] Functional differences of the medial amygdala and medial preoptic area in regulation of conspecific odor preferences (2008)
  • Author(s): Dhungel, S., Urakawa, S., Kondo, Y. and Sakuma, Y.
  • Organizer: JAPAN/CHINA Joint Symposium for"Strategies to Reduce Risks on the Brain Development Contingent to Urbanization"
  • Place of Presentation: Tsukuba, Japan
  • Year and Date: 20080000
• [Presentation] 幼若期の生育環境と性衝動-動物モデルからの検討 (2007)
  • Author(s): 近藤保彦
  • Organizer: 第52回日本=性研究会議
  • Place of Presentation: 東京
  • Year and Date: 20070000
• [Presentation] 雄ラットの性指向性調節における扁桃体内側核および内側視索前野の役割 (2007)
  • Author(s): ドゥンゲルスニル・浦川将・近藤保彦・佐久間康夫
  • Organizer: 第84回日本生理学会大会発表
  • Place of Presentation: 大阪
  • Year and Date: 20070000
• [Presentation] 豊かな環境は雄ラット性行動時の社会的接触を減少させる (2007)
  • Author(s): 浦川将・近藤保彦・西野仁雄・佐久間康夫
  • Organizer: 第84回日本生理学会大会発表
  • Place of Presentation: 大阪
  • Year and Date: 20070000
• [Presentation] 生育環境とストレス反応性・性行動 (2007)
  • Author(s): 近藤保彦・浦川将・佐久間康夫
  • Organizer: シンポジウム「ストレスと性機能障害」第17回日本性機能学会中部総会
  • Place of Presentation: 福井
  • Year and Date: 20070000
• [Presentation] Sexual behavior in male rats reared in conventional and enriched environment (2007)
  • Author(s): Urakawa, S., Kondo, Y., Mitsushima, D. and Sakuma, Y.
  • Organizer: Society for Behavioral Neuroendocrinology
  • Place of Presentation: Pacific Grove, CA
  • Year and Date: 20070000
• [Presentation] Medial amygdala and preoptic area regulate conspecific odor preference in male rat (2007)
  • Author(s): Dhungel, S., Urakawa, S., Kondo, Y. and Sakuma, Y.
  • Organizer: Society for Behavioral Neuroendocrinology
  • Place of Presentation: Pacific Grove, CA
  • Year and Date: 20070000
• [Presentation] 幼少期における豊かな環境飼育はオープンフィールドでの雄ラット性行動を減弱する (2007)
  • Author(s): 浦川将・近藤保彦・美津島大・西野仁雄・佐久間康夫
  • Organizer: 日本神経科学学会第30回大会(Neuro2007)
  • Place of Presentation: 横浜
  • Year and Date: 20070000
• [Presentation] Functional diversity of the medial amygdala and the preoptic area in controlling sexual preference of male rats (2007)
  • Author(s): ドゥンゲルスニル・浦川将・近藤保彦・佐久間康夫
  • Organizer: 日本動物心理学会第67回大会
  • Place of Presentation: 東京
  • Year and Date: 20070000
• [Presentation] ラット視索前野性的二型核に発現するソマトスタチンの性差 (2006)
  • Author(s): 折笠千登世・近藤保彦・佐久間康夫
  • Organizer: 日本神経科学学会第29回大会発表
  • Place of Presentation: 京都
  • Year and Date: 20060000
• [Presentation] 雌ラットの性行動による条件性場所選好に及ぼすナロキソン投与の効果 (2006)
  • Author(s): 堀部晨, 近藤保彦, 岩崎庸男, 山田一夫
  • Organizer: 日本動物心理学会第66回大会
  • Place of Presentation: 京都
  • Year and Date: 20060000
• [Presentation] 雌マウス性行動における嗅覚条件付け (2006)
  • Author(s): 近藤保彦・曽布川亜弓・加藤雅裕・佐久間康夫・斎藤徹
  • Organizer: 日本動物心理学会第66回大会
  • Place of Presentation: 京都
  • Year and Date: 20060000
• [Presentation] 豊かな飼育環境によってもたらされる雄ラット社会行動の変化 (2006)
  • Author(s): 浦川将・近藤保彦・佐久間康夫
  • Organizer: 日本動物心理学会第66回大会
  • Place of Presentation: 京都
  • Year and Date: 20060000
• [Presentation] 性成熟後に見られる雄セット性指向性の柔軟性 (2006)
  • Author(s): 近藤保彦
  • Organizer: ワークショップ「日本における行動神経内分泌学研究の動向」日本動物心理学会第66回大会
  • Place of Presentation: 京都
  • Year and Date: 20060000
• [Presentation] Olfactory conditioning of copulatory behavior in male mice (2006)
  • Author(s): Kondo, Y., Sobukawa, A., Katou, M., Sakuma, Y. and Saito, T.R.
  • Organizer: Society for Behavioral Neuroendocrinology
  • Place of Presentation: Pittsburgh, PA
  • Year and Date: 20060000
• [Presentation] Sexually dimorphic exression of somatostatin gene in the developing rat preoptic area (2006)
  • Author(s): Orikasa, C., Kondo, Y. and Sakuma, Y.
  • Organizer: Society for Behavioral Neuroendocrinology
  • Place of Presentation: Pittsburgh, PA
  • Year and Date: 20060000
• [Presentation] Effects of opiate antagonist on mating-induced conditioned place preference in female rats (2006)
  • Author(s): Yamada, K., Horibe, S., Kondo, Y.
  • Organizer: Society for Behavioral Neuroendocrinology
  • Place of Presentation: Pittsburgh, PA
  • Year and Date: 20060000
• [Book] 心理学検定模擬問題集「神経・生理領域」(日本心理学諸学会連合 心理学検定局) (2009)
  • Author(s): 近藤保彦
  • Publisher: 実務教育出版
• [Book] 心理学検定重要キーワード集「神経・生理領域」(日本心理学諸学会連合 心理学検定局) (2009)
  • Author(s): 近藤保彦
  • Publisher: 実務教育出版
• [Book] 幼若期の生育環境と性衝動-動物モデルからの検討.性科学ハンドブック vol.11. 思春期の性衝動-男の子の性を考える (2008)
  • Author(s): 近藤保彦
  • Total Pages: 13-30
  • Publisher: 財団法人日本性教育協会
• [Book] 脳とホルモンの行動学-行動神経内分泌学への招待
  • Author(s): 近藤保彦・小川園子・菊水健史・山田一夫・富原一哉
  • Publisher: 西村書店(近刊)