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2007 Fiscal Year Final Research Report Summary

Association between urinary albumin and cerebrovascular disease in healthy women

Research Project

Project/Area Number 18590611
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionIwate Medical University

Principal Investigator

ONODA Toshiyuki  Iwate Medical University, School of Medicine, Lecturer (00254748)

Co-Investigator(Kenkyū-buntansha) ITAI Kazuyoshi  Iwate Medical University, School of Medicine, Associate Professor (10048572)
YOSHIDA Yuki  Iwate Medical University, School of Medicine, Lecturer (80254762)
NAKAMURA Motoyuki  Iwate Medical University, School of Medicine, Professor (40172449)
SAKATA Kiyomi  Iwate Medical University, School of Medicine, Professor (50225794)
Project Period (FY) 2006 – 2007
Keywordscohort study / urine albumin to creatmme ratio / stroke registry / 脳卒中発症登録 / 心疾患発症登録
Research Abstract

The Iwate-Kenpoku cohort (Iwate-KENCO) study is designed to prospectively investigate the risks of stroke and cardiovascular disease in a general population in northern area in Japan. A baseline survey was conducted as a part of a government regulated health check up for the general population. From 2002 to 2004, 26,469 participants (9,161 males and 17,308 females) took part in the program. Of these participants, 25,713 participants were measured urinary albumin. In this study, we used subject aged 40 to 74, without history of stroke. Subjects with the following characteristics were excluded; hematuria, HbA1c>6 5% and casual blood sugar>200mg/dl. The final statistical analysis was therefore performed in 6,443 males and 13,494 females. The mean follow-up period was 2 7 years, there were 54,019 person-years of observation and 183 deaths and 232 incident cases of stroke occurred during this period for men and women. Age-adjusted and multiple adjusted hazard ratios (HR) for all-cause death and incident case of stroke were calculated in each group according to A spot urine albumin to creatinine ratio (UACR) quartile by Cox proportional hazard model. In females, the multivariable-adjusted HR (95%CI)of all-cause death for Q2, Q3 and Q4 versus Q1 was 2 43 (104, 5.69), 191 (0 80, 4 56) and 2 09 (0.85, 510). The multiple adjusted HR of incident stroke in females was 0.77 (0.40, 1.50), 1.09 (0 58, 2 03), 158 (0 86, 2 87). In females, the multivariable-adjusted HR of stroke for logarithmic UACR was 124 (106, 1.47).
These results suggest the UACR is an important marker for stroke in females.

  • Research Products

    (18 results)

All 2007 0

All Presentation (18 results)

  • [Presentation] 山間地域住民の肥満と関連要因の実態岩手県北地域コホート研究より2007

    • Author(s)
      栗林 徹, 他
    • Organizer
      第66回日本公衆衛生学会総会
    • Place of Presentation
      松山市
    • Year and Date
      20071000
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 主観的健康感と高感度CRP、尿中微量アルブミン、BNPの関連岩手県北地域コホート研究2007

    • Author(s)
      丹野 高三, 他
    • Organizer
      第66回日本公衆衛生学会総会
    • Place of Presentation
      松山市
    • Year and Date
      20071000
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 地域健診にて測定した尿中微量アルブミンが総死亡および脳卒中罹患に及ぼす影響:岩手県北地域コホート研究2007

    • Author(s)
      小野田 敏行, 他
    • Organizer
      第17回日本疫学会学術総会
    • Place of Presentation
      広島市
    • Year and Date
      2007-01-26
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 閉じこもりと介護認定との関連:岩手県北地域コホート研究2007

    • Author(s)
      安村 誠司, 他
    • Organizer
      第17回日本疫学会学術総会
    • Place of Presentation
      広島市
    • Year and Date
      2007-01-26
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 収縮期血圧と介護認定との関連:岩手県北地域コホート研究2007

    • Author(s)
      板井 一好, 他
    • Organizer
      第17回日本疫学会学術総会
    • Place of Presentation
      広島市
    • Year and Date
      2007-01-26
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] BMIおよび体重変化と介護i認定との関連岩手県北地域コホート研究2007

    • Author(s)
      栗林 徹, 他
    • Organizer
      第17回、日本疫学会学術総会
    • Place of Presentation
      広島市
    • Year and Date
      2007-01-26
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 身体活動状況と介護認定との関連:岩手県北地域コホート研究2007

    • Author(s)
      栗林 徹, 他
    • Organizer
      第17回日本疫学会学術総会
    • Place of Presentation
      広島市
    • Year and Date
      2007-01-26
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 主観的健康感生活満足感と介護認定との関連:岩手県北地域コホート研究2007

    • Author(s)
      丹野 高三, 他
    • Organizer
      第17回日本疫学会学術総会
    • Place of Presentation
      広島市
    • Year and Date
      2007-01-26
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] 脂肪酸摂取量と介護認定との関連:岩手県北地域コホート研究、第17回目本疫学会学術総会2007

    • Author(s)
      大澤 正樹, 他
    • Organizer
      第17回日本疫学会学術総会
    • Place of Presentation
      広島市
    • Year and Date
      2007-01-26
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] The effects of obesity in the rural area. Iwate-KENCO study0

    • Author(s)
      Kuribayashi T, et. al.
    • Organizer
      The 66th annual meeting of the Japan pub-lic health association
    • Place of Presentation
      Matsuyama
    • Year and Date
      00000710
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association between self-rated health and BNP, CRP and albuminuria and the long-term care insurance certificate0

    • Author(s)
      Tanno K, et. al.
    • Organizer
      The 66th annual meeting of the Japan pub-lic health association
    • Place of Presentation
      Matsuyama
    • Year and Date
      00000710
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association between urinary albumin and all-cause death and incident stroke in healthy women : Iwate-KENCO study0

    • Author(s)
      Onoda T, et. al.
    • Organizer
      The 17th annual meeting of the Japan epi-demiological association
    • Place of Presentation
      Hiroshima
    • Year and Date
      00000701
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association between' Tojikomori' and the long-term care insurance certificate : Iwate-KENCO study0

    • Author(s)
      Yasumura S, et. al.
    • Organizer
      The 17th annual meeting of the Japan epi-demiological association
    • Place of Presentation
      Hiroshima
    • Year and Date
      00000701
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association between systolic blood pressure and the long-term care insurance certificate : Iwate-KENCO study0

    • Author(s)
      Itai K, et. al.
    • Organizer
      The 17th annual meeting of the Japan epi-demiological association
    • Place of Presentation
      Hiroshima
    • Year and Date
      00000701
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association between body mass index and the long- term care insurance certificate : Iwate-KENCO study0

    • Author(s)
      Kuribayashi T, et. al.
    • Organizer
      The 17th annual meeting of the Japan epi-demiological association
    • Place of Presentation
      Hiroshima
    • Year and Date
      00000701
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association between physical status and the long-term care insurance certificate : Iwate-KENCO study0

    • Author(s)
      Kuribayashi T, et. al.
    • Organizer
      The 17th annual meeting of the Japan epi-demiological association
    • Place of Presentation
      Hiroshima
    • Year and Date
      00000701
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association between self-rated health and the long-term care insurance cerificate : Iwate-KENCO study0

    • Author(s)
      Tanno K, et. al.
    • Organizer
      The 17th annual meeting of the Japan epi-demiological association
    • Place of Presentation
      Hiroshima
    • Year and Date
      00000701
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Association between fatty acid intake and the long-term care insurance certificate : Iwate-KENCO study0

    • Author(s)
      Ohsawa M, at. al.
    • Organizer
      The 17th annual meeting of the Japan epi- demiological association
    • Place of Presentation
      Hiroshima
    • Year and Date
      00000701
    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2010-02-04  

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