Establishment of diagnostic criteria of cardiac diseases in the cases of sudden infant death

2007 Fiscal Year Final Research Report Summary

• Project/Area Number: 18590627
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Legal medicine
• Research Institution: University of Toyama (2007); Akita University (2006)
• Principal Investigator: NISHIDA Naoki University of Toyama, Faculty of Medicine, Professor (10315088)
• Project Period (FY): 2006 – 2007
• Keywords: sudden infant death / heart / cardiac conduction system / medullary arcuate nucleus / prone positioned sleeping

Research Abstract

Twenty four cases of sudden infant death under lyear old were examined systematically. Five of 24 cases showed macroscopic cardiac abnormality, which were total anomalous pulmonary venous connection (1 cases), aneurysm of sinus valsalva (2 cases), and coactation of aorta (2 cases). In a case of aneurysm of sinus valsalva showed also atrial septal defect and patatent ductus arteriosus. In microscopically, two cases showed hypertrophic cardiomyopathy, and focal myocardial infarction, respectively, and a case of rheumatic myocarditis, cytomegello myocarditis, was found respectively. In cardiac conduction system, 12 cases showed anomalous accessory connection,. Eleven of 24 cases showed aplasty or hypoplasty of medullary arcuate nucleus, and 8 of 12 cases had anomalous accessory connection in conduction system. And also, 7 cases showed all 3 factors which are brain stem abnormality, prone positioned sleeping, cardiac abnormality, and 6 cases showed 2 kind of abnormal findings. Our results showed overlapping of abnormalities of sleeping position with silent cardiac and brain stem abnormalities have the additional risk of sudden infant death.

Research Products

• [Journal Article] Indication and limitations of using palatal rugae for personal identification in edentulous cases (2008)
  • Author(s): Ohtani M, Nishida N, et. al.
  • Journal Title: Forensic Sci Int 176 Pages: 178-182
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] The sudden and unexpected death of a female-to -male trasnssexual patient (2008)
  • Author(s): Inoue H, Nishida N., et. al.
  • Journal Title: J Forensic and Legal, Med 14 Pages: 382-386
  • Description: 「研究成果報告書概要(和文)」より
  • Peer Reviewed
• [Journal Article] Indication and limitations of using palatal rugae for personal identification in edentulous cases (2008)
  • Author(s): Ohtani, M., Nishida, N., Chiba, T., Fukuda, M., Miyamoto, Y., Yoshioka, N
  • Journal Title: Forensic Sci Int 176(2-3) Pages: 178-82
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] sudden and unexpected death of a female-to -male trasnssexual patient (2007)
  • Author(s): Inoue, H., Nishida, N., Ikeda, N., Tsuji, A. Kudo, K., Hanagama, M
  • Journal Title: J Forensic and Legal Med 14 Pages: 382-386
  • Description: 「研究成果報告書概要(欧文)」より
• [Presentation] Overlapping of pathological abnormality of cardiovascular and central nervous system in the cases of sudden infant death with prone-positioned sleeping. (2006)
  • Author(s): Nishida N
  • Organizer: 5th SIDS International
  • Place of Presentation: Yokohama, Japan
  • Year and Date: 20061100
  • Description: 「研究成果報告書概要(和文)」より
• [Remarks] 「研究成果報告書概要(和文)」より
  • URL: http://www.med.u-toyama.ac.jp/legal/index.html