2009 Fiscal Year Final Research Report
Microcirculation in pancreatic islets and adipose tissue
| Project/Area Number |
18590993
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Metabolomics
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| Research Institution | Kyushu University |
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Principal Investigator |
IWASE Masanori Kyushu University, 大学院・医学研究院, 准教授 (00203381)
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| Project Period (FY) |
2006 – 2009
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| Research Abstract |
Islet of Langerhans is a small organ scattered through the pancreas. Islet has a unique microvascular system and its blood flow is meticulously regulated by some mechanisms. Glucose causes an increase in islet blood flow. In a repetitive administration of glucose, the increase in islet blood flow was smaller in the second administration than the first one. In addition, anti-diabetic and hypertensive medications affected islet blood flow, respectively. Finally, ethanol intakes during pregnancy induced impaired growth of pancreas without affecting islet blood flow in rats.
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