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2008 Fiscal Year Self-evaluation Report

The clinical research and development of non-invasive metabolic and perfusion imaging on 3T MR

Research Project

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Project/Area Number 18591335
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionUniversity of Fukui

Principal Investigator

KIMURA Hirohiko  University of Fukui, 医学部, 教授 (10242596)

Project Period (FY) 2006 – 2009
KeywordsMR / Perfusion / MRS / CASL / 脳血管障害
Research Abstract

A-1)スピンラベル法(ASL)に基づく定量的perfusion MRIの開発、データ解析手法を確立し、定量的脳血流、血液量画像を作成可能とする。
A-2)脳神経伝達物質、特にGlu、Gln、GABAを定量的にMRSにより評価する方法を確立する。
正常人および慢性閉塞性脳血管障害患者例を対象とし、perfusion、MR-OEF画像、MRSによる、虚血に伴う脳組織障害の評価の研究を行う。

  • Research Products

    (10 results)

All 2008 2007

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (4 results) Book (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Operation of bolus traking system for prediction of aortic peak enhancement at multidetector row computed tomography2008

    • Author(s)
      Isao Yamaguchi, Hiroyuki Hayashi, Masayuki Suzuki, Katsuhiro Ichikawa, Eiji Kidoya, Hirohiko Kimura
    • Journal Title

      Radiation Medicine 26(5)

      Pages: 278-286

    • Peer Reviewed
  • [Journal Article] Tissue characterization of glioma by proton MR spectroscopy and perfusion-weighted MR imaging: glioma grading and histological correlation2008

    • Author(s)
      Mariko Toyooka, Hirohiko Kimura, Hidemasa Uematsu, Yasutaka Kawamura, Hiroaki Takeuchi, Harumi Itoh
    • Journal Title

      Clinical Imaging

    • Peer Reviewed
  • [Journal Article] 臨床MRS の基礎と応用2008

    • Author(s)
      木村浩彦, 豊岡麻理子
    • Journal Title

      日本磁気共鳴医学会雑誌 28(4)

      Pages: 263-272

  • [Journal Article] ASLパーフュージョンイメージ ングの最新報告 : 臨床応用を目指した演題を中心に2007

    • Author(s)
      木村浩彦
    • Journal Title

      VIEWS RADIOLOGY 9(5)

      Pages: 16-23

  • [Presentation] 造影剤を用いない脳血流測定法CASL(Continuous Arterial Spin Labeling)の理論と臨床応用2008

    • Author(s)
      木村浩彦
    • Organizer
      第20 回日本脳循環代謝学会総会(MR 画像の進歩-どこまでできるか-)
    • Place of Presentation
      東京都
    • Year and Date
      20081100
  • [Presentation] Continuous arterial spin labeling 法による脳血流測定法 : PET dataとの全脳領域でのpixel 単位での企画2008

    • Author(s)
      木村浩彦, 豊岡麻理子, 土田龍郎, 岡沢秀彦, 新井良和
    • Organizer
      第20回臨床MR 脳機能研究会
    • Place of Presentation
      東京都
    • Year and Date
      20080300
  • [Presentation] A new ASL scheme of repeated labeling based on FAIR sequence2007

    • Author(s)
      Y. Fujiwara, H. Kimura, H. Kabasawa, Y. Ishimori, I. Yamaguchi, T. Miyati, K. Higashimura, H. Itoh
    • Organizer
      Joint annual meeting of ISMRM and ESMRMB, Proceedings
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      20070519-20070525
  • [Presentation] Perfusion imaging of glioma using continuous arterial spin labeling (CASL) : Comparison with histopathological features2007

    • Author(s)
      H.Kimura, H.Takeuchi, H.Kabaswa, M.Toyookal, N.Kosaka, H.Uematsu, H.Itoh
    • Organizer
      Joint annual meeting of ISMRM and ESMRMB Proceedings
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      20070500
  • [Book] 脳神経外科アドバンス2008

    • Author(s)
      木村浩彦(分担)
    • Total Pages
      28-37
    • Publisher
      MRI : 診断と治療社
  • [Patent(Industrial Property Rights)] MEGA PRESS 法を用いたGABA,Glu,Gln の定量方2008

    • Inventor(s)
      松田豪, 木村浩彦
    • Industrial Property Rights Holder
      GE 横河メディカルシステム(株)
    • Industrial Property Number
      特願2008-146664
    • Filing Date
      2008-06-04

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Published: 2010-06-11   Modified: 2016-04-21  

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