2007 Fiscal Year Final Research Report Summary
Predicting the tumor response to radiotherapy for high-grade gliomas: Clinical significance of hypoxia-related genes
| Project/Area Number |
18591386
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
OGAWA Kazuhiko University of the Ryukyus, 医学部附属病院, Associate Professor (40253984)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHII Yoshihiko University of the Ryukyus, Faculty of Medicine, Professor (50110507)
KINJO Takao University of the Ryukyus, Faculty of Medicine, Associate Professor (30284962)
TSUCHIDA Yukihiro University of the Ryukyus, University Hospital, Assistant Professor (90363663)
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| Project Period (FY) |
2006 – 2007
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| Keywords | High-grade gliomas / Radiotherapy / tumor response / Hypoxia |
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| Research Abstract |
1) Treatment protocol for high-grade gliomas has been established.
2) Influence of tumor cell and stroma sensitivy has been analyzed and both tumor cell and storma sensitivity were found to have influence on tumor response to radiation.
3) Clinical samples of high grade gliomas have been collected according to the protocol.
4) We are now investigating the relation between the hypoxia-related genes and tumor response to radiotherapy for high-grade gliomas.
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Research Products
(13 results)
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[Journal Article] Hyperfractionated radiotherapy and multi-agent chemotherapy (procarbazine, ACNU and vincristine) for high-grade gliomas: a prospective study.2006
Author(s)
Ogawa K, Yoshii Y, Toita T, Saito A, Kakinohana Y, Iraha S, Sugimoto K, Tsuchida Y, Tamaki W, Adachi G, Hyodo A, Murayama S.
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Journal Title
Anticancer Research 26
Pages: 2457-2462
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Phase II trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas.2006
Author(s)
Ogawa K, Yoshii Y, Inoue O, Toita T, Saito A, Kakinohana Y, Adachi G, Iraha S, Tamaki W, Sugimoto K, Hyodo A, Murayama S.
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Journal Title
British Journal of Cancer 95
Pages: 862-868
Description
「研究成果報告書概要(欧文)」より
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