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2008 Fiscal Year Self-evaluation Report

Identification of a disease gene in prostate cancer and treatment with genetically modified Herpes Simplex Virus

Research Project

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Project/Area Number 18591778
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Urology
Research InstitutionOsaka Medical College

Principal Investigator

勝岡 洋治  Osaka Medical College, 医学部, 教授 (10051757)

Project Period (FY) 2006 – 2009
KeywordsHSV / 前立腺癌 / PSM / サバイビン / splice variants
Research Abstract

HSVにおけるウイルス自体の細胞障害性と複製という特性を利用して、特定の腫瘍細胞のみでHSVの複製をおこさせる組み換えHSVを作成し標的細胞のみを殺傷する、癌治療を対象とした新しい見地からの遺伝子治療を前立腺癌に焦点をおいて検討している。

  • Research Products

    (1 results)

All 2008

All Journal Article (1 results)

  • [Journal Article] Anticancer effect of combination therapy of VP16 and fosfesterol in hormone-refractory prostate cancer2008

    • Author(s)
      Azuma H, Sakamoto T, Kiyama S, Ubai T, Kotake Y, Inamoto T, Takahara K, Nishimura Y, Segawa N, Katsuoka Y
    • Journal Title

      Am J Clin Oncol 31(2)

      Pages: 188-194

URL: 

Published: 2010-06-11   Modified: 2016-04-21  

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