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2008 Fiscal Year Self-evaluation Report

A study of sperm fertilizing ability and intracellular signal transduction

Research Project

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Project/Area Number 18591796
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Obstetrics and gynecology
Research InstitutionTokyo Medical and Dental University

Principal Investigator

SHIMIZU Yasufumi  Tokyo Medical and Dental University, 医学部附属病院, 講師 (80242197)

Project Period (FY) 2006 – 2009
Keywords精子 / 受精能 / 細胞内情報伝達系
Research Abstract

1) ハムスター精子での走化性の検討
2) 精子受精能促進因子の解明
3) ヒト精子のhyperactivation誘引物質の同定
4) ヒト子宮頚管粘液が精子細胞内カルシウムを上昇させるか否かの検討
5) hyperactivationと細胞内カルシウム濃度の変化との関係についての検討
6) ヒト精子の先体反応発現における細胞内ける細胞内情報伝達系の関与についての検討

  • Research Products

    (3 results)

All 2008

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results)

  • [Journal Article] Increase in the concentration of cytosolic-free calcium induced by human follicular fluid was decreased in single human spermatozoa with abnormal morphology2008

    • Author(s)
      Shimizu Y, Minagichi R, Ishikawa T, Harada T, Yoshiki N, Kubota T
    • Journal Title

      Reproductive Medicine and Biology 7

      Pages: 143-149

    • Peer Reviewed
  • [Journal Article] Methylation of the calcium channel-related gene, CACNA2D3, is frequent and a poor prognostic factor in gastric cancer2008

    • Author(s)
      Wanajo A, Sasaki A, Nagasaki H, Shimida S, Otubo T, Owaki S, Shimizu Y, Eishi Y, Kojima K, Nakajima Y, Kawano T, Yuasa Y, Akiyama Y
    • Journal Title

      Gastroent erology 135

      Pages: 580-590

    • Peer Reviewed
  • [Presentation] 体外受精における精子自動分析装置(CASA・SQA)の意義のついての検討2008

    • Author(s)
      原田竜也、清水康史、岩田未菜、田島麻記子、石川智則、久保田俊郎
    • Organizer
      第60回日本産科婦人科学会学術講演会
    • Place of Presentation
      横浜
    • Year and Date
      2008-04-13

URL: 

Published: 2010-06-11   Modified: 2016-04-21  

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