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2008 Fiscal Year Final Research Report

Evolution of the Rh superfamily genes

Research Project

  • PDF
Project/Area Number 18770002
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Genetics/Genome dynamics
Research InstitutionIbaraki University (2007-2008)
Yamagata University (2006)

Principal Investigator

KITANO Takashi  Ibaraki University, 工学部, 准教授 (90400564)

Project Period (FY) 2006 – 2008
Keywords系統樹 / 多型 / ゲノム / 進化 / 遺伝子
Research Abstract

スナヤツメから3種類のRhスーパーファミリー遺伝子の塩基配列を決定した。そのうちの1つは、他の脊椎動物のRHBGと、また、残りの2つは他の脊椎動物のRHCGとそれぞれクラスターを形成した。一方、ナメクジウオからは2種類の遺伝子の存在が示され、これらは3'UTRに大きな構造的差異があった。系統解析から、これらはナメクジウオの系統で独自に重複したと考えられた。さらに、Rh遺伝子スーパーファミリー全体の進化解析も行った。

  • Research Products

    (6 results)

All 2009 2008 2007 2006

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (2 results)

  • [Journal Article] Distinct carboxy-terminus of the B subunit for factor XIII in a population-associated major phenotype: the first case of complete allele-specific alternative splicing products in the coagulation and fibrinolytic systems.2009

    • Author(s)
      Iwata H, Kitano T, Umetsu K, Yuasa I, Yamazaki K, Kemkes-Matthes B, and Ichinose A.
    • Journal Title

      Journal of thrombosis and haemostasis. (In press)

    • Peer Reviewed
  • [Journal Article] Relic of ancient recombinations in gibbon ABO blood group genes deciphered through phylogenetic network analysis.2009

    • Author(s)
      Kitano T, Noda R, Takenaka O, and Saitou N.
    • Journal Title

      Molecular Phylogenetics and Evolution 51

      Pages: 465-471

    • Peer Reviewed
  • [Journal Article] Tempo and mode of evolution of the Rh blood group genes before and after gene duplication.2007

    • Author(s)
      Kitano T, Umetsu K, Tian W, Yamazaki K, and Saitou N.
    • Journal Title

      Immunogenetics. 59

      Pages: 427-431

    • Peer Reviewed
  • [Journal Article] Origin and evolution of gene for prolactin-induced protein.2006

    • Author(s)
      Kitano T, Tian W, Umetsu K, Yuasa I, Yamazaki K, Saitou N and Osawa M.
    • Journal Title

      Gene 383

      Pages: 64-70

    • Peer Reviewed
  • [Presentation] Rh式血液型遺伝子スーパーファミリーの進化2008

    • Author(s)
      北野 誉
    • Organizer
      日本進化学会
    • Place of Presentation
      東京
    • Year and Date
      2008-08-22
  • [Presentation] 脊椎動物におけるRh遺伝子族の進化2006

    • Author(s)
      北野 誉
    • Organizer
      日本進化学会
    • Place of Presentation
      東京
    • Year and Date
      2006-08-30

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Published: 2010-06-10   Modified: 2016-04-21  

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