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2020 Fiscal Year Final Research Report

Importance of lanthanides in microorganisms

Research Project

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Project/Area Number 18H02129
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 38020:Applied microbiology-related
Research InstitutionOkayama University

Principal Investigator

Tani Akio  岡山大学, 資源植物科学研究所, 准教授 (00335621)

Project Period (FY) 2018-04-01 – 2021-03-31
KeywordsMethylotroph / Lanthanides / Methanol dehydrogenase
Outline of Final Research Achievements

Methylobacterium species are phytosymbionts utilizing methanol emitted from plants. They utilize two different methanol dehydrogenases (MDHs) that require calcium and lanthanides. We examined the regulation mechanism of Ln-dependent gene expression, and found factors involved in the regulation. On the other hand, Ln-dependent MDH gene is encoded in many bacterial genomes. We found and characterized new Ln-dependent methylotrophs.

Free Research Field

Microbiology

Academic Significance and Societal Importance of the Research Achievements

ランタノイドは天然には広く存在するが実験室環境には存在しないため、それに依存する微生物の生育、代謝系の制御の理解は自然界での微生物の振る舞いを理解する上で重要である。本研究ではランタノイドを生育に要求する微生物を新規に見いだし、その依存性をゲノムや酵素遺伝子の観点から証明した。またMethylobacterium属細菌についてランタノイドによる代謝酵素遺伝子制御のメカニズムの一端を明らかに出来た。

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Published: 2022-01-27  

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