生理活性タンパク質の細胞内移送の新機軸

Products Report

• Project/Area Number: 18H04017
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Review Section: Medium-sized Section 47:Pharmaceutical sciences and related fields
• Research Institution: Kyoto University
• Principal Investigator: Shiroh Futaki 京都大学, 化学研究所, 教授 (50199402)
• Project Period (FY): 2018-04-01 – 2021-03-31

Research Products

• [Journal Article] Protein Delivery to Cytosol by Cell-Penetrating Peptide Bearing Tandem Repeat Penetration-Accelerating Sequence (2022)
  • Author(s): Akiko Okuda, Shiroh Futaki
  • Journal Title: Methods Mol. Biol. Volume: 2383 Pages: 265-273
  • DOI: 10.1007/978-1-0716-1752-6_18
  • Peer Reviewed
• [Journal Article] Artificial Nanocage Formed via Self-assembly of β-Annulus Peptide for Delivering Biofunctional Pproteins into Cell Interiors (2022)
  • Author(s): Kentarou Sakamoto, Hiroto Furukawa, Jan Vincent V. Arafiles, Miki Imanishi, Kazunori Matsuura, Shiroh Futaki
  • Journal Title: Bioconjug. Chem. Volume: 33 Pages: 311-320
  • DOI: 10.1021/acs.bioconjchem.1c00534
  • Peer Reviewed
• [Journal Article] Stearylated Macropinocytosis-inducing Peptides Facilitating the Cellular Uptake of Small Extracellular Vesicles (2022)
  • Author(s): Yuna Nakagawa, Jan Vincent V. Arafiles, Yoshimasa Kawaguchi, Ikuhiko Nakase, Hisaaki Hirose, Shiroh Futaki
  • Journal Title: Bioconjug. Chem. Volume: 33 Pages: 869-880
  • DOI: 10.1021/acs.bioconjchem.2c00113
  • Peer Reviewed
• [Patent(Industrial Property Rights)] 細胞質送達ペプチド (2022)
  • Inventor(s): 二木史朗、坂本健太郎、秋柴美沙穂
  • Industrial Property Rights Holder: 国立大学法人京都大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特許第7068711号
  • Overseas
• [Patent(Industrial Property Rights)] 細胞質送達ペプチド (2021)
  • Inventor(s): 二木史朗、坂本健太郎、秋柴美沙穂
  • Industrial Property Rights Holder: 国立大学法人京都大学
  • Industrial Property Number: US11179471B2