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2019 Fiscal Year Annual Research Report

ジョーンズ行列型光コヒーレンスエラストグラフィー法の確立と皮膚科学への応用

Research Project

Project/Area Number 18J13841
Research InstitutionUniversity of Tsukuba

Principal Investigator

李 恩  筑波大学, 数理物質科学研究科, 特別研究員(DC2)

Project Period (FY) 2018-04-25 – 2020-03-31
KeywordsOCT / JM-OCE / birefringence / displacement / deformation / polarization / biomechanics
Outline of Annual Research Achievements

The active compression based Jones matrix optical coherence elastography (JM-OCE) has been established. The hardware of the system and its post-processing method has been upgraded and modified, such that the imaging depth range has been enlarged and the quality and accuracy of local birefringence imaging for tissues has been improved.Finally, the simultaneous imaging of intensity OCT, local birefringence, in-plane lateral and axial displacement, microstructural decorrelation / deformation (MSD) for biological tissues has been demonstrated. The results indicate that JM-OCE would provide more comprehensive information for biological tissue investigation.

Research Progress Status

令和元年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和元年度が最終年度であるため、記入しない。

  • Research Products

    (5 results)

All 2020 2019

All Journal Article (3 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (2 results)

  • [Journal Article] Tissue analysis using optical and mechanical tissue properties obtained by polarization-sensitive optical coherence elastography2020

    • Author(s)
      Miyazawa Arata、Makita Shuichi、Li En、Yamazaki Kohei、Kobayashi Masaki、Sakai Shingo、Yasuno Yoshiaki
    • Journal Title

      Proceedings of SPIE

      Volume: 11242 Pages: 1~5

    • DOI

      https://doi.org/10.1117/12.2544687

  • [Journal Article] Depth-resolved investigation of multiple optical properties and wrinkle morphology in eye-corner area by multi-functional Jones matrix optical coherence tomography2020

    • Author(s)
      Yamazaki Kohei、Li En、Miyazawa Arata、Kobayashi Masaki、Sayo Tetsuya、Makita Shuichi、Takahashi Yoshito、Yasuno Yoshiaki、Sakai Shingo
    • Journal Title

      Proceedings of SPIE

      Volume: 11211 Pages: 1~6

    • DOI

      https://doi.org/10.1117/12.2543977

  • [Journal Article] Polarization-sensitive optical coherence elastography2019

    • Author(s)
      Miyazawa Arata、Makita Shuichi、Li En、Yamazaki Kohei、Kobayashi Masaki、Sakai Shingo、Yasuno Yoshiaki
    • Journal Title

      Biomedical Optics Express

      Volume: 10 Pages: 5162~5162

    • DOI

      https://doi.org/10.1364/BOE.10.005162

    • Peer Reviewed / Open Access
  • [Presentation] Tissue analysis using optical and mechanical tissue properties obtained by polarization-sensitive optical coherence elastography2020

    • Author(s)
      Miyazawa Arata
    • Organizer
      SPIE Photonics West (BiOS) 2020
  • [Presentation] Depth-resolved investigation of multiple optical properties and wrinkle morphology in eye-corner area by multi-functional Jones matrix optical coherence tomography2020

    • Author(s)
      Yamazaki Kohei
    • Organizer
      SPIE Photonics West (BiOS) 2020

URL: 

Published: 2021-01-27  

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