Development of ambient ionization mass spectrometry using dark current discharge with argon gas

2020 Fiscal Year Final Research Report

• Project/Area Number: 18K05179
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 34020:Analytical chemistry-related
• Research Institution: Yokohama City University
• Principal Investigator: Sekimoto Kanako 横浜市立大学, 生命ナノシステム科学研究科(八景キャンパス), 准教授 (40583399)
• Project Period (FY): 2018-04-01 – 2021-03-31
• Keywords: 質量分析 / アルゴン / 暗流 / DART（リアルタイム直接分析法） / アンビエントイオン化

Outline of Final Research Achievements

Direct analysis in real time (DART) is one of ambient ionization mass spectrometry. Although DART has been performed with a great amount of success in various fields, use of helium gas and glow discharge (classified with selfsustaining discharge) causes limitations for utility. In this study, a novel ionization technique using argon gas and atmospheric pressure dark current discharge (classified with non-selfsustaining discharge) has been developed. This technique has ionization efficiency and mechanism comparable to those of conventional DART.

Free Research Field

質量分析学

Academic Significance and Societal Importance of the Research Achievements

本研究で見出された「暗流励起アルゴン」によるイオン化は，アンビエント質量分析法の1つであるリアルタイム直接分析法（DART）の問題を抜本的に解決する，安価で・低電力で・どこでも継続的に計測できる質量分析法の要素技術を提供するものである．